| Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex DD Sarbassov, DA Guertin, SM Ali, DM Sabatini Science 307 (5712), 1098-1101, 2005 | 8350 | 2005 |
| CellProfiler: image analysis software for identifying and quantifying cell phenotypes AE Carpenter, TR Jones, MR Lamprecht, C Clarke, IH Kang, O Friman, ... Genome biology 7, 1-11, 2006 | 5577 | 2006 |
| Defining the role of mTOR in cancer DA Guertin, DM Sabatini Cancer cell 12 (1), 9-22, 2007 | 3542 | 2007 |
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton DD Sarbassov, SM Ali, DH Kim, DA Guertin, RR Latek, ... Current biology 14 (14), 1296-1302, 2004 | 3419 | 2004 |
| Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα, but not S6K1 DA Guertin, DM Stevens, CC Thoreen, AA Burds, NY Kalaany, J Moffat, ... Developmental cell 11 (6), 859-871, 2006 | 1937 | 2006 |
| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ... science 335 (6076), 1638-1643, 2012 | 1322 | 2012 |
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ... Cell 146 (3), 408-420, 2011 | 1318 | 2011 |
| An expanding role for mTOR in cancer DA Guertin, DM Sabatini Trends in molecular medicine 11 (8), 353-361, 2005 | 723 | 2005 |
| The pharmacology of mTOR inhibition DA Guertin, DM Sabatini Science signaling 2 (67), pe24-pe24, 2009 | 674 | 2009 |
| mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice DA Guertin, DM Stevens, M Saitoh, S Kinkel, K Crosby, JH Sheen, ... Cancer cell 15 (2), 148-159, 2009 | 489 | 2009 |
| Spatiotemporal structure of cell fate decisions in murine neural crest R Soldatov, M Kaucka, ME Kastriti, J Petersen, T Chontorotzea, ... Science 364 (6444), eaas9536, 2019 | 418 | 2019 |
| PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors J Sanchez-Gurmaches, CM Hung, CA Sparks, Y Tang, H Li, DA Guertin Cell metabolism 16 (3), 348-362, 2012 | 410 | 2012 |
| T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ... Immunity 39 (6), 1043-1056, 2013 | 379 | 2013 |
| Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed J Sanchez-Gurmaches, DA Guertin Nature communications 5 (1), 4099, 2014 | 377 | 2014 |
| Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy CA Sparks, DA Guertin Oncogene 29 (26), 3733-3744, 2010 | 376 | 2010 |
| Cytokinesis in eukaryotes DA Guertin, S Trautmann, D McCollum Microbiology and Molecular Biology Reviews 66 (2), 155-178, 2002 | 339 | 2002 |
| Adipocyte lineages: tracing back the origins of fat J Sanchez-Gurmaches, DA Guertin Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (3), 340-351, 2014 | 312 | 2014 |
| Emerging complexities in adipocyte origins and identity J Sanchez-Gurmaches, CM Hung, DA Guertin Trends in cell biology 26 (5), 313-326, 2016 | 252 | 2016 |
| mTOR-dependent cell survival mechanisms CM Hung, L Garcia-Haro, CA Sparks, DA Guertin Cold Spring Harbor perspectives in biology 4 (12), a008771, 2012 | 236 | 2012 |
| The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast DA Guertin, L Chang, F Irshad, KL Gould, D McCollum The EMBO journal, 2000 | 215 | 2000 |
David M. SabatiniInstitute of Organic Chemistry and Biochemistry of the CAS在 uochb.cas.cz 的电子邮件经过验证
