Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer E Pérez-Gómez, C Andradas, S Blasco-Benito, MM Caffarel, ... Journal of the National Cancer Institute 107 (6), djv077, 2015 | 122 | 2015 |
Activity-based probes for functional interrogation of retaining β-glucuronidases L Wu, J Jiang, Y Jin, WW Kallemeijn, CL Kuo, M Artola, W Dai, C Van Elk, ... Nature chemical biology 13 (8), 867-873, 2017 | 109 | 2017 |
An overview of activity-based probes for glycosidases L Wu, Z Armstrong, SP Schröder, C de Boer, M Artola, JMFG Aerts, ... Current opinion in chemical biology 53, 25-36, 2019 | 105 | 2019 |
Plant glycosides and glycosidases: a treasure-trove for therapeutics K Kytidou, M Artola, HS Overkleeft, JMFG Aerts Frontiers in plant science 11, 357, 2020 | 96 | 2020 |
Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ LB Ruiz-Avila, S Huecas, M Artola, A Vergoñós, E Ramírez-Aportela, ... ACS chemical biology 8 (9), 2072-2083, 2013 | 80 | 2013 |
New synthetic inhibitors of fatty acid synthase with anticancer activity C Turrado, T Puig, J García-Cárceles, M Artola, B Benhamú, ... Journal of medicinal chemistry 55 (11), 5013-5023, 2012 | 80 | 2012 |
Fabry disease: molecular basis, pathophysiology, diagnostics and potential therapeutic directions K Kok, KC Zwiers, RG Boot, HS Overkleeft, JMFG Aerts, M Artola Biomolecules 11 (2), 271, 2021 | 76 | 2021 |
1, 6-Cyclophellitol cyclosulfates: a new class of irreversible glycosidase inhibitor M Artola, L Wu, MJ Ferraz, CL Kuo, L Raich, IZ Breen, WA Offen, ... ACS central science 3 (7), 784-793, 2017 | 72 | 2017 |
Discovering the microbial enzymes driving drug toxicity with activity-based protein profiling PB Jariwala, SJ Pellock, D Goldfarb, EW Cloer, M Artola, JB Simpson, ... ACS chemical biology 15 (1), 217-225, 2019 | 64 | 2019 |
In vivo inactivation of glycosidases by conduritol B epoxide and cyclophellitol as revealed by activity‐based protein profiling CL Kuo, WW Kallemeijn, LT Lelieveld, M Mirzaian, I Zoutendijk, A Vardi, ... The FEBS journal 286 (3), 584-600, 2019 | 62 | 2019 |
Glycosphingolipids and lysosomal storage disorders as illustrated by gaucher disease JMFG Aerts, CL Kuo, LT Lelieveld, DEC Boer, MJC van der Lienden, ... Current opinion in chemical biology 53, 204-215, 2019 | 58 | 2019 |
Chemical proteomics identifies SLC25A20 as a functional target of the ingenol class of actinic keratosis drugs CG Parker, CA Kuttruff, A Galmozzi, L Jørgensen, CH Yeh, DJ Hermanson, ... ACS Central Science 3 (12), 1276-1285, 2017 | 58 | 2017 |
Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-l-Arabinofuranosidases NGS McGregor, M Artola, A Nin-Hill, D Linzel, M Haon, J Reijngoud, ... Journal of the American Chemical Society 142 (10), 4648-4662, 2020 | 47 | 2020 |
Glycosphingolipids and infection. Potential new therapeutic avenues JMFG Aerts, M Artola, M Van Eijk, MJ Ferraz, RG Boot Frontiers in cell and developmental biology 7, 324, 2019 | 42 | 2019 |
The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors M Artola, LB Ruíz-Avila, E Ramírez-Aportela, RF Martínez, ... Chemical Science 8 (2), 1525-1534, 2017 | 42 | 2017 |
Carba-cyclophellitols are neutral retaining-glucosidase inhibitors TJM Beenakker, DPA Wander, WA Offen, M Artola, L Raich, MJ Ferraz, ... Journal of the American Chemical Society 139 (19), 6534-6537, 2017 | 38 | 2017 |
Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines SP Schröder, JW van de Sande, WW Kallemeijn, CL Kuo, M Artola, ... Chemical communications 53 (93), 12528-12531, 2017 | 38 | 2017 |
Effective GTP-replacing FtsZ inhibitors and antibacterial mechanism of action M Artola, LB Ruiz-Avila, A Vergoñós, S Huecas, L Araujo-Bazán, ... ACS Chemical Biology 10 (3), 834-843, 2015 | 38 | 2015 |
Functionalized cyclophellitols are selective glucocerebrosidase inhibitors and induce a bona fide neuropathic Gaucher model in zebrafish M Artola, CL Kuo, LT Lelieveld, RJ Rowland, GA van der Marel, ... Journal of the American Chemical Society 141 (10), 4214-4218, 2019 | 36 | 2019 |
Activity-based probes for glycosidases: profiling and other applications CL Kuo, E van Meel, K Kytidou, WW Kallemeijn, M Witte, HS Overkleeft, ... Methods in enzymology 598, 217-235, 2018 | 33 | 2018 |