t4 workshop report: State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology N Alépée, A Bahinski, M Daneshian, B De Wever, E Fritsche, A Goldberg, ... Altex 31 (4), 441, 2014 | 287 | 2014 |
Metabolomics in toxicology and preclinical research T Ramirez, M Daneshian, H Kamp, FY Bois, MR Clench, M Coen, ... Altex 30 (2), 209, 2013 | 253 | 2013 |
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ... Altex 37 (3), 365, 2020 | 238 | 2020 |
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity D Pamies, P Barrera, K Block, G Makri, A Kumar, D Wiersma, L Smirnova, ... Altex 34 (3), 362, 2017 | 218 | 2017 |
toxicometabolomics M Bouhifd, T Hartung, HT Hogberg, A Kleensang, L Zhao Journal of Applied Toxicology 33 (12), 1365-1383, 2013 | 195 | 2013 |
Food for Thought…: Developmental Neurotoxicity–Challenges in the 21st Century and In Vitro Opportunities L Smirnova, HT Hogberg, M Leist, T Hartung Altex 31 (2), 129, 2014 | 181 | 2014 |
Recommendation on test readiness criteria for new approach methods (NAM) in toxicology: exemplified for developmental neurotoxicity (DNT) A Bal-Price, HT Hogberg, KM Crofton, M Daneshian, RE FitzGerald, ... Altex 35 (3), 306, 2018 | 169 | 2018 |
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes A Bal-Price, KM Crofton, M Leist, S Allen, M Arand, T Buetler, N Delrue, ... Archives of toxicology 89, 269-287, 2015 | 168 | 2015 |
Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2 CK Bullen, HT Hogberg, A Bahadirli-Talbott, WR Bishai, T Hartung, ... ALTEX-Alternatives to animal experimentation 37 (4), 665-671, 2020 | 164 | 2020 |
Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis O Kilic, D Pamies, E Lavell, P Schiapparelli, Y Feng, T Hartung, ... Lab on a Chip 16 (21), 4152-4162, 2016 | 160 | 2016 |
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use M Aschner, S Ceccatelli, M Daneshian, E Fritsche, N Hasiwa, T Hartung, ... Altex 34 (1), 49, 2017 | 157 | 2017 |
Application of micro-electrode arrays (MEAs) as an emerging technology for developmental neurotoxicity: evaluation of domoic acid-induced effects in primary cultures of rat … HT Hogberg, T Sobanski, A Novellino, M Whelan, DG Weiss, AK Bal-Price Neurotoxicology 32 (1), 158-168, 2011 | 156 | 2011 |
Rotenone exerts developmental neurotoxicity in a human brain spheroid model D Pamies, K Block, P Lau, L Gribaldo, CA Pardo, P Barreras, L Smirnova, ... Toxicology and applied pharmacology 354, 101-114, 2018 | 136 | 2018 |
Biological and medical applications of a brain-on-a-chip D Pamies, T Hartung, HT Hogberg Experimental biology and medicine 239 (9), 1096-1107, 2014 | 136 | 2014 |
A human stem cell-based model for identifying adverse effects of organic and inorganic chemicals on the developing nervous system L Buzanska, J Sypecka, S Nerini-Molteni, A Compagnoni, HT Hogberg, ... Stem cells 27 (10), 2591-2601, 2009 | 133 | 2009 |
In vitro developmental neurotoxicity (DNT) testing: relevant models and endpoints AK Bal-Price, HT Hogberg, L Buzanska, P Lenas, E van Vliet, T Hartung Neurotoxicology 31 (5), 545-554, 2010 | 132 | 2010 |
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis L Smirnova, G Harris, J Delp, M Valadares, D Pamies, HT Hogberg, ... Archives of toxicology 90, 2725-2743, 2016 | 116 | 2016 |
mRNA Expression is a Relevant Tool to Identify Developmental Neurotoxicants Using an In Vitro Approach HT Hogberg, A Kinsner-Ovaskainen, S Coecke, T Hartung, AK Bal-Price Toxicological Sciences 113 (1), 95-115, 2010 | 116 | 2010 |
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes E Fritsche, P Grandjean, KM Crofton, M Aschner, A Goldberg, T Heinonen, ... Toxicology and applied pharmacology 354, 3-6, 2018 | 113 | 2018 |
t4 workshop report: pathways of toxicity A Kleensang, A Maertens, M Rosenberg, S Fitzpatrick, J Lamb, ... Altex 31 (1), 53, 2014 | 112 | 2014 |