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Bruce Lamb
Bruce Lamb
Director, Stark Neurosciences Research Institute at Indiana University School of Medicine
在 iu.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Inflammation as a central mechanism in Alzheimer's disease
JW Kinney, SM Bemiller, AS Murtishaw, AM Leisgang, AM Salazar, ...
Alzheimer's & Dementia: Translational Research & Clinical Interventions 4 …, 2018
18292018
ApoE promotes the proteolytic degradation of Aβ
Q Jiang, CYD Lee, S Mandrekar, B Wilkinson, P Cramer, N Zelcer, ...
Neuron 58 (5), 681-693, 2008
11252008
TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
TR Jay, CM Miller, PJ Cheng, LC Graham, S Bemiller, ML Broihier, G Xu, ...
Journal of Experimental Medicine 212 (3), 287-295, 2015
7072015
Regulation of tau pathology by the microglial fractalkine receptor
K Bhaskar, M Konerth, ON Kokiko-Cochran, A Cardona, RM Ransohoff, ...
Neuron 68 (1), 19-31, 2010
6452010
Vascular contributions to cognitive impairment and dementia including Alzheimer's disease
HM Snyder, RA Corriveau, S Craft, JE Faber, SM Greenberg, D Knopman, ...
Alzheimer's & Dementia 11 (6), 710-717, 2015
6372015
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
A Salehi, JD Delcroix, PV Belichenko, K Zhan, C Wu, JS Valletta, ...
Neuron 51 (1), 29-42, 2006
6082006
CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models
S Lee, NH Varvel, ME Konerth, G Xu, AE Cardona, RM Ransohoff, ...
The American journal of pathology 177 (5), 2549-2562, 2010
5232010
Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain
N Maphis, G Xu, ON Kokiko-Cochran, S Jiang, A Cardona, RM Ransohoff, ...
Brain 138 (6), 1738-1755, 2015
5122015
Introduction and expression of the 400 kilobase precursor amyloid protein gene in transgenic mice
BT Lamb, SS Sisodia, AM Lawler, HH Slunt, CA Kitt, WG Kearns, ...
Nature genetics 5 (1), 22-30, 1993
4301993
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model
CA Tagge, AM Fisher, OV Minaeva, A Gaudreau-Balderrama, ...
Brain 141 (2), 422-458, 2018
4252018
Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer's disease
TR Jay, AM Hirsch, ML Broihier, CM Miller, LE Neilson, RM Ransohoff, ...
Journal of Neuroscience 37 (3), 637-647, 2017
4162017
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours
KK Youngren, D Coveney, X Peng, C Bhattacharya, LS Schmidt, ...
Nature 435 (7040), 360-364, 2005
4022005
Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for β-amyloid peptide over-production and localization in Alzheimer’s disease
WH Yu, A Kumar, C Peterhoff, LS Kulnane, Y Uchiyama, BT Lamb, ...
The international journal of biochemistry & cell biology 36 (12), 2531-2540, 2004
3792004
Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
K Ghosal, DL Vogt, M Liang, Y Shen, BT Lamb, SW Pimplikar
Proceedings of the National Academy of Sciences 106 (43), 18367-18372, 2009
3122009
Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling
G Gunner, L Cheadle, KM Johnson, P Ayata, A Badimon, E Mondo, ...
Nature neuroscience 22 (7), 1075-1088, 2019
2602019
TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy
SM Bemiller, TJ McCray, K Allan, SV Formica, G Xu, G Wilson, ...
Molecular neurodegeneration 12, 1-12, 2017
2482017
The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease
G Aliev, MA Smith, D Seyidova, ML Neal, BT Lamb, A Nunomura, ...
Brain Pathology 12 (1), 21-35, 2002
2182002
Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models
Y Yang, NH Varvel, BT Lamb, K Herrup
Journal of Neuroscience 26 (3), 775-784, 2006
2172006
The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease
PJ Cheng-Hathaway, EG Reed-Geaghan, TR Jay, BT Casali, SM Bemiller, ...
Molecular neurodegeneration 13, 1-12, 2018
1992018
The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events
K Bhaskar, M Miller, A Chludzinski, K Herrup, M Zagorski, BT Lamb
Molecular neurodegeneration 4, 1-18, 2009
1982009
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