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| Preexisting and de novo humoral immunity to SARS-CoV-2 in humans KW Ng, N Faulkner, GH Cornish, A Rosa, R Harvey, S Hussain, R Ulferts, ... Science 370 (6522), 1339-1343, 2020 | 941 | 2020 |
| HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells P Cherepanov, G Maertens, P Proost, B Devreese, J Van Beeumen, ... Journal of Biological Chemistry 278 (1), 372-381, 2003 | 913 | 2003 |
| Retroviral intasome assembly and inhibition of DNA strand transfer S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov Nature 464 (7286), 232-236, 2010 | 793 | 2010 |
| The structural biology of HIV-1: mechanistic and therapeutic insights A Engelman, P Cherepanov Nature Reviews Microbiology 10 (4), 279-290, 2012 | 736 | 2012 |
| Mobile DNA III NL Craig John Wiley & Sons, 2020 | 724 | 2020 |
| LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells G Maertens, P Cherepanov, W Pluymers, K Busschots, E De Clercq, ... Journal of Biological Chemistry 278 (35), 33528-33539, 2003 | 640 | 2003 |
| LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration MC Shun, NK Raghavendra, N Vandegraaff, JE Daigle, S Hughes, ... Genes & development 21 (14), 1767-1778, 2007 | 582 | 2007 |
| Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75 P Cherepanov, ALB Ambrosio, S Rahman, T Ellenberger, A Engelman Proceedings of the National Academy of Sciences 102 (48), 17308-17313, 2005 | 482 | 2005 |
| The mechanism of retroviral integration from X-ray structures of its key intermediates GN Maertens, S Hare, P Cherepanov Nature 468 (7321), 326-329, 2010 | 363 | 2010 |
| Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance S Hare, AM Vos, RF Clayton, JW Thuring, MD Cummings, P Cherepanov Proceedings of the National Academy of Sciences 107 (46), 20057-20062, 2010 | 362 | 2010 |
| Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase P Cherepanov, E Devroe, PA Silver, A Engelman Journal of Biological Chemistry 279 (47), 48883-48892, 2004 | 334 | 2004 |
| Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572) S Hare, SJ Smith, M Métifiot, A Jaxa-Chamiec, Y Pommier, SH Hughes, ... Molecular pharmacology 80 (4), 565-572, 2011 | 316 | 2011 |
| The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication A Engelman, P Cherepanov PLoS pathogens 4 (3), e1000046, 2008 | 308 | 2008 |
| Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75 P Cherepanov, ZYJ Sun, S Rahman, G Maertens, G Wagner, A Engelman Nature structural & molecular biology 12 (6), 526-532, 2005 | 299 | 2005 |
| Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 249 | 2020 |
| The effect of spike mutations on SARS-CoV-2 neutralization C Rees-Spear, L Muir, SA Griffith, J Heaney, Y Aldon, JL Snitselaar, ... Cell reports 34 (12), 2021 | 247 | 2021 |
| Retroviral DNA integration P Lesbats, AN Engelman, P Cherepanov Chemical reviews 116 (20), 12730-12757, 2016 | 238 | 2016 |
| Structure-based modeling of the functional HIV-1 intasome and its inhibition L Krishnan, X Li, HL Naraharisetty, S Hare, P Cherepanov, A Engelman Proceedings of the National Academy of Sciences 107 (36), 15910-15915, 2010 | 222 | 2010 |
| A tripartite DNA-binding element, comprised of the nuclear localization signal and two AT-hook motifs, mediates the association of LEDGF/p75 with chromatin in vivo F Turlure, G Maertens, S Rahman, P Cherepanov, A Engelman Nucleic acids research 34 (5), 1653-1665, 2006 | 218 | 2006 |
