Understanding biological hydrogen transfer through the lens of temperature dependent kinetic isotope effects JP Klinman, AR Offenbacher Accounts of chemical research 51 (9), 1966-1974, 2018 | 117 | 2018 |
pH-dependent cis→ trans isomerization rates for azobenzene dyes in aqueous solution NJ Dunn, WH Humphries IV, AR Offenbacher, TL King, JA Gray The Journal of Physical Chemistry A 113 (47), 13144-13151, 2009 | 94 | 2009 |
Origins of enzyme catalysis: Experimental findings for C–H activation, new models, and their relevance to prevailing theoretical constructs JP Klinman, AR Offenbacher, S Hu Journal of the American Chemical Society 139 (51), 18409-18427, 2017 | 69 | 2017 |
Hydrogen–deuterium exchange of lipoxygenase uncovers a relationship between distal, solvent exposed protein motions and the thermal activation barrier for catalytic proton … AR Offenbacher, S Hu, EM Poss, CAM Carr, AD Scouras, DM Prigozhin, ... ACS central science 3 (6), 570-579, 2017 | 63 | 2017 |
13C ENDOR Spectroscopy of Lipoxygenase–Substrate Complexes Reveals the Structural Basis for C–H Activation by Tunneling M Horitani, AR Offenbacher, CAM Carr, T Yu, V Hoeke, GE Cutsail III, ... Journal of the American Chemical Society 139 (5), 1984-1997, 2017 | 63 | 2017 |
Proton-coupled electron transfer and redox-active tyrosines: Structure and function of the tyrosyl radicals in ribonucleotide reductase and photosystem II BA Barry, J Chen, J Keough, D Jenson, A Offenbacher, C Pagba The journal of physical chemistry letters 3 (4), 543-554, 2012 | 49 | 2012 |
An intrinsically disordered photosystem II subunit, PsbO, provides a structural template and a sensor of the hydrogen-bonding network in photosynthetic water oxidation AR Offenbacher, BC Polander, BA Barry Journal of Biological Chemistry 288 (40), 29056-29068, 2013 | 37 | 2013 |
Redox-linked structural changes in ribonucleotide reductase AR Offenbacher, IR Vassiliev, MR Seyedsayamdost, J Stubbe, BA Barry Journal of the American Chemical Society 131 (22), 7496-7497, 2009 | 35 | 2009 |
Detecting and characterizing the kinetic activation of thermal networks in proteins: Thermal transfer from a distal, solvent-exposed loop to the active site in soybean lipoxygenase JPT Zaragoza, A Nguy, N Minnetian, Z Deng, AT Iavarone, ... The Journal of Physical Chemistry B 123 (41), 8662-8674, 2019 | 32 | 2019 |
Fatty acid allosteric regulation of CH activation in plant and animal lipoxygenases AR Offenbacher, TR Holman Molecules 25 (15), 3374, 2020 | 27 | 2020 |
Hydrogen–deuterium exchange reveals long-range dynamical allostery in soybean lipoxygenase AR Offenbacher, AT Iavarone, JP Klinman Journal of Biological Chemistry 293 (4), 1138-1148, 2018 | 27 | 2018 |
Redox-active tyrosine residues in pentapeptides IR Vassiliev, AR Offenbacher, BA Barry The Journal of Physical Chemistry B 109 (48), 23077-23085, 2005 | 27 | 2005 |
Biophysical characterization of a disabled double mutant of soybean lipoxygenase: the “undoing” of precise substrate positioning relative to metal cofactor and an identified … S Hu, AR Offenbacher, EM Thompson, CL Gee, J Wilcoxen, CAM Carr, ... Journal of the American Chemical Society 141 (4), 1555-1567, 2019 | 26 | 2019 |
The soybean lipoxygenase–substrate complex: Correlation between the properties of tunneling-ready states and ENDOR-detected structures of ground states AR Offenbacher, A Sharma, PE Doan, JP Klinman, BM Hoffman Biochemistry 59 (7), 901-910, 2020 | 25 | 2020 |
Redox-linked changes to the hydrogen-bonding network of ribonucleotide reductase β2 AR Offenbacher, EC Minnihan, JA Stubbe, BA Barry Journal of the American Chemical Society 135 (17), 6380-6383, 2013 | 25 | 2013 |
Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2 WC Tsai, NC Gilbert, A Ohler, M Armstrong, S Perry, C Kalyanaraman, ... Bioorganic & medicinal chemistry 46, 116349, 2021 | 24 | 2021 |
Redox-linked conformational control of proton-coupled electron transfer: Y122 in the ribonucleotide reductase β2 subunit AR Offenbacher, LA Burns, CD Sherrill, BA Barry The Journal of Physical Chemistry B 117 (28), 8457-8468, 2013 | 22 | 2013 |
Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase JPT Zaragoza, AR Offenbacher, S Hu, CL Gee, ZM Firestein, N Minnetian, ... Proceedings of the National Academy of Sciences 120 (10), e2211630120, 2023 | 21 | 2023 |
Kinetic Characterization of the C–H Activation Step for the Lipoxygenase from the Pathogenic Fungus Magnaporthe oryzae: Impact of N-Linked Glycosylation A Kostenko, K Ray, AT Iavarone, AR Offenbacher Biochemistry 58 (29), 3193-3203, 2019 | 17 | 2019 |
Impact of local electrostatics on the redox properties of tryptophan radicals in azurin: Implications for redox-active tryptophans in proton-coupled electron transfer KJ Tyson, AN Davis, JL Norris, LJ Bartolotti, EG Hvastkovs, ... The Journal of Physical Chemistry Letters 11 (7), 2408-2413, 2020 | 15 | 2020 |