The tissue kallikrein family of serine proteases: functional roles in human disease and potential as clinical biomarkers JA Clements, NM Willemsen, SA Myers, Y Dong Critical reviews in clinical laboratory sciences 41 (3), 265-312, 2004 | 288 | 2004 |
The Expanded Human Kallikrein (KLK) Gene Family: Genomic Organisation, Tissue-Specific Expression and Potential Functions J Clements, J Hooper, Y Dong, T Harvey Walter de Gruyter 382 (1), 5-14, 2001 | 199 | 2001 |
Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs): KLK4 and PAR-2 are co-expressed during prostate cancer progression AJ Ramsay, Y Dong, ML Hunt, ML Linn, H Samaratunga, JA Clements, ... Journal of Biological Chemistry 283 (18), 12293-12304, 2008 | 170 | 2008 |
Human Kallikrein 4 (KLK4) Is Highly Expressed in Serous Ovarian Carcinomas Y Dong, A Kaushal, L Bui, S Chu, PJ Fuller, J Nicklin, H Samaratunga, ... Clinical cancer research 7 (8), 2363-2371, 2001 | 166 | 2001 |
Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours Y Dong, MD Walsh, MC Cummings, RG Wright, SK Khoo, PG Parsons, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 1997 | 152 | 1997 |
Differential Splicing of KLK5 and KLK7 in Epithelial Ovarian Cancer Produces Novel Variants with Potential as Cancer Biomarkers Y Dong, A Kaushal, M Brattsand, J Nicklin, JA Clements Clinical Cancer Research 9 (5), 1710-1720, 2003 | 145 | 2003 |
Increased expression of cyclin‐dependent kinase inhibitor 2 (CDKN2A) gene product P16 INK4A in ovarian cancer is associated with progression and … Y Dong, MD Walsh, MA McGuckin, BB Gabrielli, MC Cummings, ... International journal of cancer 74 (1), 57-63, 1997 | 141 | 1997 |
Kallikrein-Related Peptidase 7 Promotes Multicellular Aggregation via the α5β1 Integrin Pathway and Paclitaxel Chemoresistance in Serous Epithelial Ovarian … Y Dong, OL Tan, D Loessner, C Stephens, C Walpole, GM Boyle, ... Cancer research 70 (7), 2624-2633, 2010 | 110 | 2010 |
Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer Y Dong, MD Walsh, MA McGuckin, MC Cummings, BG Gabrielli, ... International journal of cancer 74 (4), 407-415, 1997 | 104 | 1997 |
Compartmentalized expression of kallikrein 4 (KLK4/hK4) isoforms in prostate cancer: nuclear, cytoplasmic and secreted forms Y Dong, LT Bui, DM Odorico, OL Tan, SA Myers, H Samaratunga, ... Endocrine-related cancer 12 (4), 875-889, 2005 | 76 | 2005 |
Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts C Fan, Y Dong, Y Xie, Y Su, X Zhang, D Leavesley, Z Upton International journal of molecular medicine 36 (4), 985-991, 2015 | 70 | 2015 |
Paclitaxel Resistance and Multicellular Spheroid Formation are Induced by Kallikrein-Related Peptidase 4 in Serous Ovarian Cancer Cells in an Ascites Mimicking Microenvironment Y Dong, C Stephens, C Walpole, JE Swedberg, GM Boyle, PG Parsons, ... PlosOne, 2013 | 69 | 2013 |
Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy Y Dong, SJ Berners-Price, DR Thorburn, T Antatis, J Dickinson, T Hurst, ... Biochemical Pharmacology 53 (11), 1673-1682, 1997 | 64 | 1997 |
Metastasis of ovarian cancer is mediated by kallikrein related peptidases Y Dong, D Loessner, H Irving-Rodgers, A Obermair, JL Nicklin, ... Clinical & experimental metastasis 31, 135-147, 2014 | 63 | 2014 |
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs) AJ Ramsay, JC Reid, MN Adams, H Samaratunga, Y Dong, JA Clements, ... Walter de Gruyter 389 (6), 653-668, 2008 | 52 | 2008 |
Kallikrein-related peptidase (KLK) family mRNA variants and protein isoforms in hormone-related cancers: do they have a function? OL Tan, AK Whitbread, JA Clements, Y Dong Walter de Gruyter 387 (6), 697-705, 2006 | 49 | 2006 |
The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration Y Dong, Y He, L de Boer, MS Stack, JW Lumley, JA Clements, JD Hooper Journal of Biological Chemistry 287 (13), 9792-9803, 2012 | 48 | 2012 |
Investigating the potential of Shikonin as a novel hypertrophic scar treatment C Fan, Y Xie, Y Dong, Y Su, Z Upton Journal of Biomedical Science 22, 1-13, 2015 | 34 | 2015 |
A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival J Batra, CM Nagle, T O'Mara, M Higgins, Y Dong, OL Tan, F Lose, ... BMC cancer 11, 1-11, 2011 | 33 | 2011 |
Transcriptional regulation of differentiation, selective toxicity and ATGCAAAT binding of bisbenzimidazole derivatives in human melanoma cells SSC Wong, RA Sturm, J Michel, XM Zhang, PAC Danoy, K McGregor, ... Biochemical pharmacology 47 (5), 827-837, 1994 | 33 | 1994 |