Long Distance Measurements up to 160 Å in the GroEL Tetradecamer Using Q‐Band DEER EPR Spectroscopy T Schmidt, MA Wälti, JL Baber, EJ Hustedt, GM Clore Angewandte Chemie International Edition 55 (51), 15905-15909, 2016 | 187 | 2016 |
Basic amino-acid side chains regulate transmembrane integrin signalling C Kim, T Schmidt, EG Cho, F Ye, TS Ulmer, MH Ginsberg Nature 481 (7380), 209-213, 2012 | 137 | 2012 |
Mutation in CPT1C associated with pure autosomal dominant spastic paraplegia C Rinaldi, T Schmidt, AJ Situ, JO Johnson, PR Lee, K Chen, LC Bott, ... JAMA neurology 72 (5), 561-570, 2015 | 83 | 2015 |
Evolutionarily conserved dual lysine motif determines the non-chaperone function of secreted Hsp90alpha in tumour progression M Zou, A Bhatia, H Dong, P Jayaprakash, J Guo, D Sahu, Y Hou, F Tsen, ... Oncogene 36 (15), 2160-2171, 2017 | 77 | 2017 |
Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells JM Kim, K Kim, T Schmidt, V Punj, H Tucker, JC Rice, TS Ulmer, W An Nucleic acids research 43 (18), 8868-8883, 2015 | 76 | 2015 |
Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR SA Kotler, V Tugarinov, T Schmidt, A Ceccon, DS Libich, R Ghirlando, ... Proceedings of the National Academy of Sciences 116 (9), 3562-3571, 2019 | 71 | 2019 |
The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract JM Bravo-Arredondo, NC Kegulian, T Schmidt, NK Pandey, AJ Situ, ... Journal of Biological Chemistry 293 (51), 19613-19623, 2018 | 44 | 2018 |
Small molecule inhibitors of the annexin A2 heterotetramer prevent human papillomavirus type 16 infection AW Woodham, JR Taylor, AI Jimenez, JG Skeate, T Schmidt, HE Brand, ... Journal of Antimicrobial Chemotherapy 70 (6), 1686-1690, 2015 | 43 | 2015 |
Interaction of huntingtin exon-1 peptides with lipid-based micellar nanoparticles probed by solution NMR and Q-band pulsed EPR A Ceccon, T Schmidt, V Tugarinov, SA Kotler, CD Schwieters, GM Clore Journal of the American Chemical Society 140 (20), 6199-6202, 2018 | 41 | 2018 |
Structural and thermodynamic basis of proline-induced transmembrane complex stabilization T Schmidt, AJ Situ, TS Ulmer Scientific reports 6 (1), 29809, 2016 | 35 | 2016 |
Characterization of membrane protein interactions by isothermal titration calorimetry AJ Situ, T Schmidt, P Mazumder, TS Ulmer Journal of molecular biology 426 (21), 3670-3680, 2014 | 34 | 2014 |
Time-resolved DEER EPR and solid-state NMR afford kinetic and structural elucidation of substrate binding to Ca2+-ligated calmodulin T Schmidt, J Jeon, WM Yau, CD Schwieters, R Tycko, GM Clore Proceedings of the National Academy of Sciences 119 (6), e2122308119, 2022 | 33 | 2022 |
Chaperonin GroEL accelerates protofibril formation and decorates fibrils of the Het-s prion protein MA Wälti, T Schmidt, DT Murray, H Wang, JE Hinshaw, GM Clore Proceedings of the National Academy of Sciences 114 (34), 9104-9109, 2017 | 28 | 2017 |
Quantitative Resolution of Monomer‐Dimer Populations by Inversion Modulated DEER EPR Spectroscopy T Schmidt, R Ghirlando, J Baber, GM Clore ChemPhysChem 17 (19), 2987-2991, 2016 | 28 | 2016 |
Submillisecond Freezing Permits Cryoprotectant-Free EPR Double Electron Electron Resonance Spectroscopy T Schmidt, J Jeon, Y Okuno, SC Chiliveri, GM Clore ChemPhysChem, 2020 | 27 | 2020 |
Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR T Schmidt, CD Schwieters, GM Clore Proceedings of the National Academy of Sciences 116 (36), 17809-17816, 2019 | 25 | 2019 |
Annular anionic lipids stabilize the integrin αIIbβ3 transmembrane complex T Schmidt, JE Suk, F Ye, AJ Situ, P Mazumder, MH Ginsberg, TS Ulmer Journal of Biological Chemistry 290 (13), 8283-8293, 2015 | 25 | 2015 |
A conserved ectodomain-transmembrane domain linker motif tunes the allosteric regulation of cell surface receptors T Schmidt, F Ye, AJ Situ, W An, MH Ginsberg, TS Ulmer Journal of Biological Chemistry 291 (34), 17536-17546, 2016 | 21 | 2016 |
Probing Conformational States of the Finger and Thumb Subdomains of HIV-1 Reverse Transcriptase Using Double Electron–Electron Resonance Electron Paramagnetic Resonance … T Schmidt, L Tian, GM Clore Biochemistry 57 (5), 489-493, 2018 | 14 | 2018 |
Direct evaluation of protein–lipid contacts reveals protein membrane immersion and isotropic bicelle structure T Schmidt, AJ Situ, TS Ulmer The Journal of Physical Chemistry Letters 7 (21), 4420-4426, 2016 | 12 | 2016 |