| Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis B Isermann, IA Vinnikov, T Madhusudhan, S Herzog, M Kashif, J Blautzik, ... Nature medicine 13 (11), 1349-1358, 2007 | 472 | 2007 |
| Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy K Shahzad, F Bock, W Dong, H Wang, S Kopf, S Kohli, S Ranjan, J Wolter, ... Kidney international 87 (1), 74-84, 2015 | 451 | 2015 |
| Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy T Madhusudhan, H Wang, W Dong, S Ghosh, F Bock, VR Thangapandi, ... Nature communications 6 (1), 6496, 2015 | 177 | 2015 |
| Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc F Bock, K Shahzad, H Wang, S Stoyanov, J Wolter, W Dong, PG Pelicci, ... Proceedings of the National Academy of Sciences 110 (2), 648-653, 2013 | 167 | 2013 |
| Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes T Madhusudhan, H Wang, BK Straub, E Gröne, Q Zhou, K Shahzad, ... Blood, The Journal of the American Society of Hematology 119 (3), 874-883, 2012 | 150 | 2012 |
| The emerging role of coagulation proteases in kidney disease T Madhusudhan, BA Kerlin, B Isermann Nature reviews nephrology 12 (2), 94, 2016 | 128 | 2016 |
| Caspase-1, but not caspase-3, promotes diabetic nephropathy K Shahzad, F Bock, I Gadi, S Kohli, S Nazir, S Ghosh, S Ranjan, H Wang, ... Journal of the American Society of Nephrology 27 (8), 2270-2275, 2016 | 119 | 2016 |
| Lipid presentation by the protein C receptor links coagulation with autoimmunity N Müller-Calleja, A Hollerbach, J Royce, S Ritter, D Pedrosa, ... Science 371 (6534), eabc0956, 2021 | 99 | 2021 |
| Activated protein C ameliorates renal ischemia-reperfusion injury by restricting Y-box binding protein-1 ubiquitination W Dong, H Wang, K Shahzad, F Bock, S Ranjan, J Wolter, S Kohli, ... Journal of the American Society of Nephrology 26 (11), 2789-2799, 2015 | 96 | 2015 |
| Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cβ-, phosphoinositide 3-kinase-, and nitric oxide … S Seehaus, K Shahzad, M Kashif, IA Vinnikov, M Schiller, H Wang, ... Circulation 120 (9), 774-784, 2009 | 89 | 2009 |
| Farnesoid X receptor agonism protects against diabetic tubulopathy: potential add-on therapy for diabetic nephropathy A Marquardt, S Ghosh, S Kohli, J Manoharan, A ElWakiel, I Gadi, F Bock, ... Journal of the American Society of Nephrology 28 (11), 3182-3189, 2017 | 80 | 2017 |
| Homeostatic nuclear RAGE–ATM interaction is essential for efficient DNA repair V Kumar, T Fleming, S Terjung, C Gorzelanny, C Gebhardt, R Agrawal, ... Nucleic acids research 45 (18), 10595-10613, 2017 | 79 | 2017 |
| An exosite-specific ssDNA aptamer inhibits the anticoagulant functions of activated protein C and enhances inhibition by protein C inhibitor J Müller, B Isermann, C Dücker, M Salehi, M Meyer, M Friedrich, ... Chemistry & biology 16 (4), 442-451, 2009 | 77 | 2009 |
| The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition H Wang, I Vinnikov, K Shahzad, F Bock, S Ranjan, J Wolter, M Kashif, ... Thrombosis and haemostasis 108 (12), 1141-1153, 2012 | 74 | 2012 |
| Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy H Wang, T Madhusudhan, T He, B Hummel, S Schmidt, IA Vinnikov, ... Blood, The Journal of the American Society of Hematology 117 (19), 5231-5242, 2011 | 55 | 2011 |
| Chronic obstructive pulmonary disease and the cardiovascular system: vascular repair and regeneration as a therapeutic target S Karnati, M Seimetz, F Kleefeldt, A Sonawane, T Madhusudhan, ... Frontiers in Cardiovascular Medicine 8, 649512, 2021 | 52 | 2021 |
| Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function T Madhusudhan, H Wang, S Ghosh, W Dong, V Kumar, MM Al-Dabet, ... Blood, The Journal of the American Society of Hematology 130 (12), 1445-1455, 2017 | 33 | 2017 |
| Role of coagulation and fibrinolysis in lung and renal fibrosis C Ruppert, P Markart, M Wygrecka, KT Preissner, A Günther Hämostaseologie 28 (01/02), 30-36, 2008 | 32 | 2008 |
| Podocyte integrin-β3 and activated protein C coordinately restrict RhoA signaling and ameliorate diabetic nephropathy T Madhusudhan, S Ghosh, H Wang, W Dong, D Gupta, A Elwakiel, ... Journal of the American Society of Nephrology 31 (8), 1762-1780, 2020 | 27 | 2020 |
| Nuclear factor erythroid-derived 2 (Nfe2) regulates JunD DNA-binding activity via acetylation: a novel mechanism regulating trophoblast differentiation M Kashif, A Hellwig, S Hashemolhosseini, V Kumar, F Bock, H Wang, ... Journal of Biological Chemistry 287 (8), 5400-5411, 2012 | 27 | 2012 |
