The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ... Nature medicine 23 (5), 631-637, 2017 | 381 | 2017 |
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes R Xue, MD Lynes, JM Dreyfuss, F Shamsi, TJ Schulz, H Zhang, TL Huang, ... Nature medicine 21 (7), 760-768, 2015 | 271 | 2015 |
12-Lipoxygenase regulates cold adaptation and glucose metabolism by producing the omega-3 lipid 12-HEPE from brown fat LO Leiria, CH Wang, MD Lynes, K Yang, F Shamsi, M Sato, S Sugimoto, ... Cell metabolism 30 (4), 768-783. e7, 2019 | 158 | 2019 |
Cardiolipin synthesis in brown and beige fat mitochondria is essential for systemic energy homeostasis EG Sustarsic, T Ma, MD Lynes, M Larsen, I Karavaeva, JF Havelund, ... Cell metabolism 28 (1), 159-174. e11, 2018 | 145 | 2018 |
β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis C Cero, HJ Lea, KY Zhu, F Shamsi, YH Tseng, AM Cypess JCI insight 6 (11), 2021 | 123 | 2021 |
Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue M Rosina, V Ceci, R Turchi, C Li, N Borcherding, F Sciarretta, ... Cell metabolism 34 (4), 533-548. e12, 2022 | 119 | 2022 |
Cell types promoting goosebumps form a niche to regulate hair follicle stem cells Y Shwartz, M Gonzalez-Celeiro, CL Chen, HA Pasolli, SH Sheu, SMY Fan, ... Cell 182 (3), 578-593. e19, 2020 | 113 | 2020 |
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice CH Wang, M Lundh, A Fu, R Kriszt, TL Huang, MD Lynes, LO Leiria, ... Science translational medicine 12 (558), eaaz8664, 2020 | 103 | 2020 |
The evolving view of thermogenic adipocytes—ontogeny, niche and function F Shamsi, CH Wang, YH Tseng Nature Reviews Endocrinology 17 (12), 726-744, 2021 | 100 | 2021 |
Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes R Kriszt, S Arai, H Itoh, MH Lee, AG Goralczyk, XM Ang, AM Cypess, ... Scientific Reports 7 (1), 1383, 2017 | 90 | 2017 |
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis F Shamsi, R Xue, TL Huang, M Lundh, Y Liu, LO Leiria, MD Lynes, ... Nature communications 11 (1), 1421, 2020 | 81 | 2020 |
Defining the lineage of thermogenic perivascular adipose tissue AR Angueira, AP Sakers, CD Holman, L Cheng, MN Arbocco, F Shamsi, ... Nature metabolism 3 (4), 469-484, 2021 | 79 | 2021 |
Cold-activated lipid dynamics in adipose tissue highlights a role for cardiolipin in thermogenic metabolism MD Lynes, F Shamsi, EG Sustarsic, LO Leiria, CH Wang, SC Su, ... Cell reports 24 (3), 781-790, 2018 | 77 | 2018 |
Vascular smooth muscle-derived Trpv1+ progenitors are a source of cold-induced thermogenic adipocytes F Shamsi, M Piper, LL Ho, TL Huang, A Gupta, A Streets, MD Lynes, ... Nature metabolism 3 (4), 485-495, 2021 | 71 | 2021 |
Characterization of transcript enrichment and detection bias in single-nucleus RNA-seq for mapping of distinct human adipocyte lineages A Gupta, F Shamsi, N Altemose, GF Dorlhiac, AM Cypess, AP White, ... Genome research 32 (2), 242-257, 2022 | 46 | 2022 |
Cell-autonomous light sensitivity via Opsin3 regulates fuel utilization in brown adipocytes M Sato, T Tsuji, K Yang, X Ren, JM Dreyfuss, TL Huang, CH Wang, ... PLoS biology 18 (2), e3000630, 2020 | 45 | 2020 |
Identification and characterization of a supraclavicular brown adipose tissue in mice Q Mo, J Salley, T Roshan, LA Baer, FJ May, EJ Jaehnig, AC Lehnig, ... JCI insight 2 (11), 2017 | 38 | 2017 |
MicroRNA regulation of brown adipogenesis and thermogenic energy expenditure F Shamsi, H Zhang, YH Tseng Frontiers in Endocrinology 8, 205, 2017 | 37 | 2017 |
Protocols for generation of immortalized human brown and white preadipocyte cell lines F Shamsi, YH Tseng Thermogenic Fat: Methods and Protocols, 77-85, 2017 | 31 | 2017 |
Integrating extracellular flux measurements and genome-scale modeling reveals differences between brown and white adipocytes AK Ramirez, MD Lynes, F Shamsi, R Xue, YH Tseng, CR Kahn, S Kasif, ... Cell reports 21 (11), 3040-3048, 2017 | 24 | 2017 |