Opportunities and challenges for transcriptome-wide association studies M Wainberg, N Sinnott-Armstrong, N Mancuso, AN Barbeira, DA Knowles, ... Nature genetics 51 (4), 592-599, 2019 | 686 | 2019 |
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ... Nature genetics 50 (4), 538-548, 2018 | 434 | 2018 |
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021 | 330 | 2021 |
Probabilistic fine-mapping of transcriptome-wide association studies N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ... Nature genetics 51 (4), 675-682, 2019 | 297 | 2019 |
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc The American Journal of Human Genetics 100 (3), 473-487, 2017 | 260 | 2017 |
Local genetic correlation gives insights into the shared genetic architecture of complex traits H Shi, N Mancuso, S Spendlove, B Pasaniuc The American Journal of Human Genetics 101 (5), 737-751, 2017 | 255 | 2017 |
Genetic control of expression and splicing in developing human brain informs disease mechanisms RL Walker, G Ramaswami, C Hartl, N Mancuso, MJ Gandal, ... Cell 179 (3), 750-771. e22, 2019 | 223 | 2019 |
The contribution of rare variation to prostate cancer heritability N Mancuso, N Rohland, KA Rand, A Tandon, A Allen, D Quinque, ... Nature genetics 48 (1), 30-35, 2016 | 163 | 2016 |
Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum MS Fejzo, OV Sazonova, JF Sathirapongsasuti, IB Hallgrímsdóttir, V Vacic, ... Nature communications 9 (1), 1178, 2018 | 151 | 2018 |
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions N Mancuso, S Gayther, A Gusev, W Zheng, KL Penney, Z Kote-Jarai, ... Nature communications 9 (1), 4079, 2018 | 140 | 2018 |
Targeted mutagenesis in a human-parasitic nematode SS Gang, ML Castelletto, AS Bryant, E Yang, N Mancuso, JB Lopez, ... PLoS pathogens 13 (10), e1006675, 2017 | 110 | 2017 |
Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture K Hou, KS Burch, A Majumdar, H Shi, N Mancuso, Y Wu, S Sankararaman, ... Nature genetics 51 (8), 1244-1251, 2019 | 105 | 2019 |
Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ... The American Journal of Human Genetics 103 (4), 535-552, 2018 | 89 | 2018 |
Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data H Shi, KS Burch, R Johnson, MK Freund, G Kichaev, N Mancuso, ... The American Journal of Human Genetics 106 (6), 805-817, 2020 | 78 | 2020 |
Accurate viral population assembly from ultra-deep sequencing data S Mangul, NC Wu, N Mancuso, A Zelikovsky, R Sun, E Eskin Bioinformatics 30 (12), i329-i337, 2014 | 60 | 2014 |
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization GA Pathak, K Singh, TW Miller-Fleming, FR Wendt, N Ehsan, K Hou, ... Nature communications 12 (1), 4569, 2021 | 56 | 2021 |
Evaluating polygenic risk scores for breast cancer in women of African ancestry Z Du, G Gao, B Adedokun, T Ahearn, KL Lunetta, G Zirpoli, MA Troester, ... JNCI: Journal of the National Cancer Institute 113 (9), 1168-1176, 2021 | 49 | 2021 |
A multi-stage genome-wide association study of uterine fibroids in African Americans JN Hellwege, JM Jeff, LA Wise, CS Gallagher, M Wellons, KE Hartmann, ... Human genetics 136, 1363-1373, 2017 | 47 | 2017 |
Leveraging expression from multiple tissues using sparse canonical correlation analysis and aggregate tests improves the power of transcriptome-wide association studies H Feng, N Mancuso, A Gusev, A Majumdar, M Major, B Pasaniuc, P Kraft PLoS genetics 17 (4), e1008973, 2021 | 45 | 2021 |
Schizophrenia Working Group of the Psychiatric Genomics C, McCarroll S, et al: Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic … A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ... Nat Genet 50 (4), 538-548, 2018 | 42 | 2018 |