Locally renewing resident synovial macrophages provide a protective barrier for the joint S Culemann, A Grüneboom, JÁ Nicolás-Ávila, D Weidner, KF Lämmle, ... Nature 572 (7771), 670-675, 2019 | 450 | 2019 |
Understanding microRNA-mediated gene regulatory networks through mathematical modelling X Lai, O Wolkenhauer, J Vera Nucleic acids research 44 (13), 6019-6035, 2016 | 180 | 2016 |
Systems biology-based investigation of cooperating microRNAs as monotherapy or adjuvant therapy in cancer X Lai, M Eberhardt, U Schmitz, J Vera Nucleic acids research 47 (15), 7753-7766, 2019 | 151 | 2019 |
Artificial intelligence in cancer target identification and drug discovery Y You, X Lai, Y Pan, H Zheng, J Vera, S Liu, S Deng, L Zhang Signal Transduction and Targeted Therapy 7 (1), 156, 2022 | 147 | 2022 |
Multicriteria optimization of biochemical systems by linear programming: Application to production of ethanol by Saccharomyces cerevisiae J Vera, P De Atauri, M Cascante, NV Torres Biotechnology and bioengineering 83 (3), 335-343, 2003 | 99 | 2003 |
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs X Lai, U Schmitz, SK Gupta, A Bhattacharya, M Kunz, O Wolkenhauer, ... Nucleic acids research 40 (18), 8818-8834, 2012 | 97 | 2012 |
Cooperative gene regulation by microRNA pairs and their identification using a computational workflow U Schmitz, X Lai, F Winter, O Wolkenhauer, J Vera, SK Gupta Nucleic acids research 42 (12), 7539-7552, 2014 | 96 | 2014 |
Systems biology of JAK-STAT signalling in human malignancies J Vera, K Rateitschak, F Lange, C Kossow, O Wolkenhauer, R Jaster Progress in biophysics and molecular biology 106 (2), 426-434, 2011 | 96 | 2011 |
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation M Faas, N Ipseiz, J Ackermann, S Culemann, A Grüneboom, F Schröder, ... Immunity 54 (11), 2531-2546. e5, 2021 | 92 | 2021 |
The AP-1 transcription factor c-Jun promotes arthritis by regulating cyclooxygenase-2 and arginase-1 expression in macrophages N Hannemann, J Jordan, S Paul, S Reid, HW Baenkler, S Sonnewald, ... The Journal of Immunology 198 (9), 3605-3614, 2017 | 90 | 2017 |
miR-638 promotes melanoma metastasis and protects melanoma cells from apoptosis and autophagy A Bhattacharya, U Schmitz, Y Raatz, M Schönherr, T Kottek, M Schauer, ... Oncotarget 6 (5), 2966, 2015 | 89 | 2015 |
Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures FM Khan, S Marquardt, SK Gupta, S Knoll, U Schmitz, A Spitschak, ... Nature communications 8 (1), 198, 2017 | 88 | 2017 |
Power-law models of signal transduction pathways J Vera, E Balsa-Canto, P Wellstead, JR Banga, O Wolkenhauer Cellular signalling 19 (7), 1531-1541, 2007 | 86 | 2007 |
The role of immune checkpoint blockade in uveal melanoma A Wessely, T Steeb, M Erdmann, L Heinzerling, J Vera, M Schlaak, ... International journal of molecular sciences 21 (3), 879, 2020 | 83 | 2020 |
EMT transcription factor ZEB1 alters the epigenetic landscape of colorectal cancer cells P Lindner, S Paul, M Eckstein, C Hampel, JK Muenzner, ... Cell death & disease 11 (2), 147, 2020 | 80 | 2020 |
Transcription factor Fra-1 targets arginase-1 to enhance macrophage-mediated inflammation in arthritis N Hannemann, S Cao, D Eriksson, A Schnelzer, J Jordan, M Eberhardt, ... The Journal of clinical investigation 129 (7), 2669-2684, 2019 | 79 | 2019 |
Emerging functional markers for cancer stem cell-based therapies: Understanding signaling networks for targeting metastasis S Marquardt, M Solanki, A Spitschak, J Vera, BM Puetzer Seminars in cancer biology 53, 90-109, 2018 | 77 | 2018 |
Whither systems medicine? R Apweiler, T Beissbarth, MR Berthold, N Blüthgen, Y Burmeister, ... Experimental & molecular medicine 50 (3), e453-e453, 2018 | 77 | 2018 |
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression D Hofbauer, D Mougiakakos, L Broggini, M Zaiss, M Büttner-Herold, ... Immunity 54 (8), 1772-1787. e9, 2021 | 69 | 2021 |
MiR-205-5p and miR-342-3p cooperate in the repression of the E2F1 transcription factor in the context of anticancer chemotherapy resistance X Lai, SK Gupta, U Schmitz, S Marquardt, S Knoll, A Spitschak, ... Theranostics 8 (4), 1106, 2018 | 69 | 2018 |