| Synergy between active efflux and outer membrane diffusion defines rules of antibiotic permeation into Gram-negative bacteria G Krishnamoorthy, IV Leus, JW Weeks, D Wolloscheck, VV Rybenkov, ... MBio 8 (5), 10.1128/mbio. 01172-17, 2017 | 172 | 2017 |
| Substrate specificities and efflux efficiencies of RND efflux pumps of Acinetobacter baumannii IV Leus, JW Weeks, V Bonifay, L Smith, S Richardson, HI Zgurskaya Journal of bacteriology 200 (13), 10.1128/jb. 00049-18, 2018 | 112 | 2018 |
| Trans-envelope multidrug efflux pumps of Gram-negative bacteria and their synergism with the outer membrane barrier HI Zgurskaya, VV Rybenkov, G Krishnamoorthy, IV Leus Research in microbiology 169 (7-8), 351-356, 2018 | 53 | 2018 |
| Cryoelectron microscopy structures of AdeB illuminate mechanisms of simultaneous binding and exporting of substrates CE Morgan, P Glaza, IV Leus, A Trinh, CC Su, M Cui, HI Zgurskaya, ... MBio 12 (1), 10.1128/mbio. 03690-20, 2021 | 44 | 2021 |
| A selective antibiotic for Lyme disease N Leimer, X Wu, Y Imai, M Morrissette, N Pitt, Q Favre-Godal, A Iinishi, ... Cell 184 (21), 5405-5418. e16, 2021 | 43 | 2021 |
| The whole is bigger than the sum of its parts: drug transport in the context of two membranes with active efflux VV Rybenkov, HI Zgurskaya, C Ganguly, IV Leus, Z Zhang, ... Chemical reviews 121 (9), 5597-5631, 2021 | 37 | 2021 |
| Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii IV Leus, J Adamiak, AN Trinh, RD Smith, L Smith, S Richardson, RK Ernst, ... Molecular microbiology 114 (6), 1049-1065, 2020 | 36 | 2020 |
| Conformational dynamics of AcrA govern multidrug efflux pump assembly AJ Hazel, N Abdali, IV Leus, JM Parks, JC Smith, HI Zgurskaya, ... ACS infectious diseases 5 (11), 1926-1935, 2019 | 32 | 2019 |
| Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa J Mehla, G Malloci, R Mansbach, CA López, R Tsivkovski, K Haynes, ... MBio 12 (1), 10.1128/mbio. 02785-20, 2021 | 28 | 2021 |
| Machine learning algorithm identifies an antibiotic vocabulary for permeating Gram-negative bacteria RA Mansbach, IV Leus, J Mehla, CA Lopez, JK Walker, VV Rybenkov, ... Journal of chemical information and modeling 60 (6), 2838-2847, 2020 | 26 | 2020 |
| Loss of RND-type multidrug efflux pumps triggers iron starvation and lipid A modifications in Pseudomonas aeruginosa JW Adamiak, V Jhawar, V Bonifay, CE Chandler, IV Leus, RK Ernst, ... Antimicrobial Agents and Chemotherapy 65 (10), 10.1128/aac. 00592-21, 2021 | 21 | 2021 |
| Mechanistic duality of bacterial efflux substrates and inhibitors: example of simple substituted cinnamoyl and naphthyl amides N D’Cunha, M Moniruzzaman, K Haynes, G Malloci, CJ Cooper, ... ACS infectious diseases 7 (9), 2650-2665, 2021 | 18 | 2021 |
| First-generation structure-activity relationship studies of 2, 3, 4, 9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors Y Li, JJ Gardner, KR Fortney, IV Leus, V Bonifay, HI Zgurskaya, ... Bioorganic & medicinal chemistry letters 29 (14), 1836-1841, 2019 | 16 | 2019 |
| A “drug sweeping” state of the TriABC triclosan efflux pump from Pseudomonas aeruginosa L Fabre, AT Ntreh, A Yazidi, IV Leus, JW Weeks, S Bhattacharyya, ... Structure 29 (3), 261-274. e6, 2021 | 15 | 2021 |
| Changes in oxidative stress intensity in blood of tumor-bearing rats following different modes of administration of rhenium-platinum system OVS K. L. Shamelashvili, N. I. Shtemenko, І. V. Leus,S. O. Babiy Ukr. Biochem. J. 88 (4), 2016 | 14 | 2016 |
| Making sense of drug-efflux transporters in the physiological environment HI Zgurskaya, JW Adamiak, IV Leus Current opinion in microbiology 69, 102179, 2022 | 13 | 2022 |
| Cryoelectron microscopy structures of AdeB illuminate mechanisms of simultaneous binding and exporting of substrates. mBio 12: e03690-20 CE Morgan, P Glaza, IV Leus, A Trinh, CC Su, M Cui, HI Zgurskaya, ... Article CAS PubMed PubMed Central, 2021 | 13 | 2021 |
| Property space mapping of Pseudomonas aeruginosa permeability to small molecules IV Leus, JW Weeks, V Bonifay, Y Shen, L Yang, CJ Cooper, D Nath, ... Scientific reports 12 (1), 8220, 2022 | 12 | 2022 |
| Functional diversity of Gram-negative permeability barriers reflected in antibacterial activities and intracellular accumulation of antibiotics IV Leus, J Adamiak, B Chandar, V Bonifay, S Zhao, SS Walker, ... Antimicrobial Agents and Chemotherapy 67 (2), e01377-22, 2023 | 11 | 2023 |
| Structure–uptake relationship studies of oxazolidinones in Gram-negative ESKAPE pathogens Z Hu, IV Leus, B Chandar, BS Sherborne, QP Avila, VV Rybenkov, ... Journal of medicinal chemistry 65 (20), 14144-14179, 2022 | 11 | 2022 |
Helen ZgurskayaProfessor of Chemistry and Biochemistry在 ou.edu 的电子邮件经过验证
