Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ... elife 3, e02523, 2014 | 1674 | 2014 |
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis K Shimada, R Skouta, A Kaplan, WS Yang, M Hayano, SJ Dixon, ... Nature chemical biology 12 (7), 497-503, 2016 | 857 | 2016 |
Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation M Hayano, WS Yang, CK Corn, NC Pagano, BR Stockwell Cell Death & Differentiation 23 (2), 270-278, 2016 | 424 | 2016 |
Cell-line selectivity improves the predictive power of pharmacogenomic analyses and helps identify NADPH as biomarker for ferroptosis sensitivity K Shimada, M Hayano, NC Pagano, BR Stockwell Cell chemical biology 23 (2), 225-235, 2016 | 271 | 2016 |
Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay AG Herman, M Hayano, MV Poyurovsky, K Shimada, R Skouta, C Prives, ... Cancer discovery 1 (4), 312-325, 2011 | 106 | 2011 |
Design and synthesis of Pictet–Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death R Skouta, M Hayano, K Shimada, BR Stockwell Bioorganic & medicinal chemistry letters 22 (17), 5707-5713, 2012 | 39 | 2012 |
Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay. Cancer Discov. 2011; 1: 312–325. doi: 10.1158/2159-8290 AG Herman, M Hayano, MV Poyurovsky, K Shimada, R Skouta, C Prives, ... CD-11-0104.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 11 | |
Probing cell death mechanisms with chemical and genetic tools M Hayano Columbia University, 2015 | | 2015 |