Elevated Golgi pH impairs terminal N‐glycosylation by inducing mislocalization of Golgi glycosyltransferases A Rivinoja, A Hassinen, N Kokkonen, A Kauppila, S Kellokumpu Journal of cellular physiology 220 (1), 144-154, 2009 | 173 | 2009 |
Functional organization of Golgi N-and O-glycosylation pathways involves pH-dependent complex formation that is impaired in cancer cells A Hassinen, FM Pujol, N Kokkonen, C Pieters, M Kihlström, K Korhonen, ... Journal of Biological Chemistry 286 (44), 38329-38340, 2011 | 139 | 2011 |
Golgi pH, its regulation and roles in human disease A Rivinoja, FM Pujol, A Hassinen, S Kellokumpu Annals of medicine 44 (6), 542-554, 2012 | 101 | 2012 |
Glycosyltransferase complexes in eukaryotes: long-known, prevalent but still unrecognized S Kellokumpu, A Hassinen, T Glumoff Cellular and molecular life sciences 73, 305-325, 2016 | 100 | 2016 |
Golgi N-glycosyltransferases form both homo-and heterodimeric enzyme complexes in live cells A Hassinen, A Rivinoja, A Kauppila, S Kellokumpu Journal of Biological Chemistry 285 (23), 17771-17777, 2010 | 97 | 2010 |
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery X Liu, S Huuskonen, T Laitinen, T Redchuk, M Bogacheva, K Salokas, ... Molecular Systems Biology 17 (11), e10396, 2021 | 67 | 2021 |
The catalysis of the 1, 1-proton transfer by α-methyl-acyl-CoA racemase is coupled to a movement of the fatty acyl moiety over a hydrophobic, methionine-rich surface P Bhaumik, W Schmitz, A Hassinen, JK Hiltunen, E Conzelmann, ... Journal of molecular biology 367 (4), 1145-1161, 2007 | 64 | 2007 |
Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway E Benedetti, M Pučić-Baković, T Keser, A Wahl, A Hassinen, JY Yang, ... Nature communications 8 (1), 1483, 2017 | 57 | 2017 |
UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression AJ Deen, UT Arasu, S Pasonen-Seppänen, A Hassinen, P Takabe, ... Cellular and Molecular Life Sciences 73, 3183-3204, 2016 | 56 | 2016 |
Organizational interplay of Golgi N-glycosyltransferases involves organelle microenvironment-dependent transitions between enzyme homo-and heteromers A Hassinen, S Kellokumpu Journal of Biological Chemistry 289 (39), 26937-26948, 2014 | 55 | 2014 |
Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo-and heteromeric complexes among hyaluronan synthases HAS1, HAS2 … G Bart, NO Vico, A Hassinen, FM Pujol, AJ Deen, A Ruusala, RH Tammi, ... Journal of Biological Chemistry 290 (18), 11479-11490, 2015 | 44 | 2015 |
N-acetylglucosaminyltransferases and nucleotide sugar transporters form multi-enzyme–multi-transporter assemblies in golgi membranes in vivo F Khoder-Agha, P Sosicka, M Escriva Conde, A Hassinen, T Glumoff, ... Cellular and molecular life sciences 76, 1821-1832, 2019 | 42 | 2019 |
A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I A Hassinen, F Khoder-Agha, E Khosrowabadi, D Mennerich, D Harrus, ... Redox biology 24, 101182, 2019 | 28 | 2019 |
Dermatan sulfate epimerase 1 and dermatan 4-O-sulfotransferase 1 form complexes that generate long epimerized 4-O-sulfated blocks E Tykesson, A Hassinen, K Zielinska, MA Thelin, G Frati, U Ellervik, ... Journal of Biological Chemistry 293 (35), 13725-13735, 2018 | 27 | 2018 |
Loss of DIAPH1 causes SCBMS, combined immunodeficiency, and mitochondrial dysfunction M Kaustio, N Nayebzadeh, R Hinttala, T Tapiainen, P Åström, K Mamia, ... Journal of Allergy and Clinical Immunology 148 (2), 599-611, 2021 | 23 | 2021 |
GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain HH Huang, A Hassinen, S Sundaram, AN Spiess, S Kellokumpu, ... Elife 4, e08916, 2015 | 22 | 2015 |
Abnormal Golgi pH homeostasis in cancer cells impairs apical targeting of carcinoembryonic antigen by inhibiting its glycosyl-phosphatidylinositol anchor-mediated association … N Kokkonen, E Khosrowabadi, A Hassinen, D Harrus, T Glumoff, ... Antioxidants & redox signaling 30 (1), 5-21, 2019 | 21 | 2019 |
The dimeric structure of wild-type human glycosyltransferase B4GalT1 D Harrus, F Khoder-Agha, M Peltoniemi, A Hassinen, L Ruddock, ... PLoS One 13 (10), e0205571, 2018 | 18 | 2018 |
Heterodimers of tyrosylprotein sulfotransferases suggest existence of a higher organization level of transferases in the membrane of the trans-Golgi apparatus C Hartmann-Fatu, F Trusch, CN Moll, I Michin, A Hassinen, S Kellokumpu, ... Journal of molecular biology 427 (6), 1404-1412, 2015 | 14 | 2015 |
Monocyte subset redistribution from blood to kidneys in patients with Puumala virus caused hemorrhagic fever with renal syndrome S Vangeti, T Strandin, S Liu, J Tauriainen, A Räisänen-Sokolowski, ... PLoS Pathogens 17 (3), e1009400, 2021 | 13 | 2021 |