Structure and dynamics of the CGRP receptor in apo and peptide-bound forms TM Josephs, MJ Belousoff, YL Liang, SJ Piper, J Cao, DJ Garama, ... Science 372 (6538), eabf7258, 2021 | 66 | 2021 |
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity JI Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... PLoS biology 19 (6), e3001295, 2021 | 54 | 2021 |
Structure and dynamics of the active Gs-coupled human secretin receptor M Dong, G Deganutti, SJ Piper, YL Liang, M Khoshouei, MJ Belousoff, ... Nature communications 11 (1), 4137, 2020 | 51 | 2020 |
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin SJ Piper, L Brillault, R Rothnagel, TI Croll, JK Box, I Chassagnon, ... Nature communications 10 (1), 1952, 2019 | 36 | 2019 |
Structural and functional diversity among agonist-bound states of the GLP-1 receptor BP Cary, G Deganutti, P Zhao, TT Truong, SJ Piper, X Liu, MJ Belousoff, ... Nature chemical biology 18 (3), 256-263, 2022 | 31 | 2022 |
Membranes under the Magnetic Lens: A Dive into the Diverse World of Membrane Protein Structures Using Cryo-EM SJ Piper, RM Johnson, D Wootten, PM Sexton Chemical Reviews 122 (17), 13989-14017, 2022 | 28 | 2022 |
Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor RM Johnson, X Zhang, SJ Piper, TJ Nettleton, TH Vandekolk, ... Biochemical and Biophysical Research Communications 578, 84-90, 2021 | 20 | 2021 |
New insights into the structure and function of class B1 GPCRs BP Cary, X Zhang, J Cao, RM Johnson, SJ Piper, EJ Gerrard, D Wootten, ... Endocrine Reviews 44 (3), 492-517, 2023 | 19 | 2023 |
Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors J Lu, SJ Piper, P Zhao, LJ Miller, D Wootten, PM Sexton International Journal of Molecular Sciences 23 (15), 8069, 2022 | 17 | 2022 |
Molecular insights into peptide agonist engagement with the PTH receptor BP Cary, EJ Gerrard, MJ Belousoff, MM Fletcher, Y Jiang, IC Russell, ... Structure 31 (6), 668-676. e5, 2023 | 7 | 2023 |
Understanding VPAC receptor family peptide binding and selectivity SJ Piper, G Deganutti, J Lu, P Zhao, YL Liang, Y Lu, MM Fletcher, ... Nature Communications 13 (1), 7013, 2022 | 7 | 2022 |
A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid L Perlaza-Jiménez, KS Tan, SJ Piper, RM Johnson, RS Bamert, ... Microbiology spectrum 10 (4), e00583-22, 2022 | 4 | 2022 |
ABC toxins: Self-assembling nanomachines for the targeted cellular delivery of bioactive proteins IR Chassagnon, SJ Piper, MJ Landsberg Comprehensive Nanoscience and Nanotechnology, 279-298, 2019 | 1 | 2019 |
Secretin amino-terminal structure-activity relationships and complementary mutagenesis at the site of docking to the secretin receptor JE Milburn, KG Harikumar, SJ Piper, S Raval, A Christopoulos, D Wootten, ... Molecular Pharmacology 101 (6), 400-407, 2022 | | 2022 |
Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins: insight into mechanisms of G protein selectivity J Mobbs, MJ Belousoff, KG Harikumar, SJ Piper, X Xu, SGB Furness, ... bioRxiv, 2021 | | 2021 |
Structural studies of the Yersinia entomophaga ABC toxin complex YenTc using cryo-EM SJ Piper | | 2019 |