Genomic subtypes of non-invasive bladder cancer with distinct metabolic profile and female gender bias in KDM6A mutation frequency CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ... Cancer cell 32 (5), 701-715. e7, 2017 | 300 | 2017 |
Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment O Alder, F Lavial, A Helness, E Brookes, S Pinho, A Chandrashekran, ... Development 137 (15), 2483-2492, 2010 | 135 | 2010 |
Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation O Alder, R Cullum, S Lee, AC Kan, W Wei, Y Yi, VC Garside, M Bilenky, ... Cell reports 9 (1), 261-271, 2014 | 134 | 2014 |
SOX9 modulates the expression of key transcription factors required for heart valve development VC Garside, R Cullum, O Alder, DY Lu, R Vander Werff, M Bilenky, Y Zhao, ... Development 142 (24), 4340-4350, 2015 | 80 | 2015 |
The next generation: using new sequencing technologies to analyse gene regulation R Cullum, O Alder, PA Hoodless Respirology 16 (2), 210-222, 2011 | 75 | 2011 |
MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation JR Pon, J Wong, S Saberi, O Alder, M Moksa, SW Grace Cheng, GB Morin, ... Nature communications 6 (1), 7953, 2015 | 64 | 2015 |
The endoplasmic reticulum coat protein II transport machinery coordinates cellular lipid secretion and cholesterol biosynthesis LGD Fryer, B Jones, EJ Duncan, CE Hutchison, T Ozkan, PA Williams, ... Journal of Biological Chemistry 289 (7), 4244-4261, 2014 | 58 | 2014 |
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight CD Hurst, G Cheng, FM Platt, MAA Castro, SM Nour-Al-Dain, P Eriksson, ... Cell Reports Medicine 2 (12), 2021 | 40 | 2021 |
PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma RL Ross, HR McPherson, L Kettlewell, SD Shnyder, CD Hurst, O Alder, ... BMC cancer 16, 1-12, 2016 | 35 | 2016 |
Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the … J Santos, C Filipe Pereira, A Di-Gregorio, T Spruce, O Alder, T Rodriguez, ... Epigenetics & chromatin 3, 1-12, 2010 | 28 | 2010 |
Genome‐wide microRNA and messenger RNA profiling in rodent liver development implicates mir302b and mir20a in repressing transforming growth factor‐beta signaling W Wei, J Hou, O Alder, X Ye, S Lee, R Cullum, A Chu, Y Zhao, SM Warner, ... Hepatology 57 (6), 2491-2501, 2013 | 23 | 2013 |
ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer E di Martino, O Alder, CD Hurst, MA Knowles Scientific Reports 9 (1), 5740, 2019 | 22 | 2019 |
An interactive analysis and exploration tool for epigenomic data H Younesy, CB Nielsen, T Möller, O Alder, R Cullum, MC Lorincz, ... Computer Graphics Forum 32 (3pt1), 91-100, 2013 | 22 | 2013 |
A regulatory network controls nephrocan expression and midgut patterning J Hou, W Wei, RS Saund, P Xiang, TJ Cunningham, Y Yi, O Alder, ... Development 141 (19), 3772-3781, 2014 | 8 | 2014 |
Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitro GA Pettitt, CD Hurst, Z Khan, HR McPherson, MC Dunning, O Alder, ... The Journal of Pathology 259 (2), 220-232, 2023 | 5 | 2023 |
Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling CD Hurst, G Cheng, FM Platt, O Alder, EVI Black, JE Burns, J Brown, ... The Journal of Pathology: Clinical Research 8 (3), 279-293, 2022 | 2 | 2022 |
Abstract LB-323: The genomic landscape of non-muscle-invasive bladder cancer: implications for molecular classification and treatment CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ... Cancer Research 76 (14_Supplement), LB-323-LB-323, 2016 | 2 | 2016 |
The Endoplasmic Reticulum COPII-Vesicle Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis LGD Fryer, B Jones, EJ Duncan, CE Hutchison, T Ozkan, PA Williams, ... Journal of Biological Chemistry, 2013 | 1 | 2013 |
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer provides improved biological, clinical and therapeutic insights CD Hurst, G Cheng, FM Platt, NADS Marzouka, P Eriksson, EVI Black, ... Cell Reports Medicine 2 (12), 2021 | | 2021 |
Mechanisms of resistance to FGFR-targeted therapy in bladder cancer GA Pettitt, HR McPherson, CD Hurst, JE Burns, OA Alder, MC Dunning, ... Cancer Research 77 (13_Supplement), 3145-3145, 2017 | | 2017 |