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Gesine Saher
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High cholesterol level is essential for myelin membrane growth
G Saher, B Brügger, C Lappe-Siefke, W Möbius, R Tozawa, MC Wehr, ...
Nature neuroscience 8 (4), 468-475, 2005
8142005
Absence of integrin α7 causes a novel form of muscular dystrophy
U Mayer, G Saher, R Fässler, A Bornemann, F Echtermeyer, H Mark, ...
Nature genetics 17 (3), 318-323, 1997
5651997
Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity
C Hammer, B Stepniak, A Schneider, S Papiol, M Tantra, M Begemann, ...
Molecular psychiatry 19 (10), 1143-1149, 2014
3862014
Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models
R Chrast, G Saher, KA Nave, MHG Verheijen
Journal of lipid research 52 (3), 419-434, 2011
3052011
Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment
D Paul, S Hoppe, G Saher, J Krijnse-Locker, R Bartenschlager
Journal of virology 87 (19), 10612-10627, 2013
2742013
The PreS2 activator MHBst of hepatitis B virus activates c‐raf‐1/Erk2 signaling in transgenic mice
E Hildt, B Munz, G Saher, K Reifenberg, PH Hofschneider
The EMBO journal, 2002
2472002
The hepatitis B virus large surface protein (LHBs) is a transcriptional activator
E Hildt, G Saher, V Bruss, PH Hofschneider
Virology 225 (1), 235-239, 1996
2221996
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis
SA Berghoff, L Spieth, T Sun, L Hosang, L Schlaphoff, C Depp, T Düking, ...
Nature neuroscience 24 (1), 47-60, 2021
1912021
Cholesterol in myelin biogenesis and hypomyelinating disorders
G Saher, SK Stumpf
Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015
1842015
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain
SA Berghoff, N Gerndt, J Winchenbach, SK Stumpf, L Hosang, F Odoardi, ...
Nature communications 8 (1), 14241, 2017
1542017
Cholesterol: a novel regulatory role in myelin formation
G Saher, S Quintes, KA Nave
The Neuroscientist 17 (1), 79-93, 2011
1472011
Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors
L Luo, MC Ambrozkiewicz, F Benseler, C Chen, E Dumontier, S Falkner, ...
Neuron 106 (1), 37-65. e5, 2020
1442020
Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet
G Saher, F Rudolphi, K Corthals, T Ruhwedel, KF Schmidt, S Löwel, ...
Nature medicine 18 (7), 1130-1135, 2012
1392012
A critical role for the cholesterol‐associated proteolipids PLP and M6B in myelination of the central nervous system
HB Werner, EM Krämer‐Albers, N Strenzke, G Saher, S Tenzer, ...
Glia 61 (4), 567-586, 2013
1352013
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction
G Saher, S Quintes, W Möbius, MC Wehr, EM Krämer-Albers, B Brügger, ...
Journal of Neuroscience 29 (19), 6094-6104, 2009
1322009
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease
C Depp, T Sun, AO Sasmita, L Spieth, SA Berghoff, T Nazarenko, ...
Nature 618 (7964), 349-357, 2023
1252023
Survival of adult neurons lacking cholesterol synthesis in vivo
U Fünfschilling, G Saher, L Xiao, W Möbius, KA Nave
BMC neuroscience 8, 1-9, 2007
1062007
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis
K Saito, V Dubreuil, Y Arai, M Wilsch-Bräuninger, D Schwudke, G Saher, ...
Proceedings of the National Academy of Sciences 106 (20), 8350-8355, 2009
1012009
Critical time window of neuronal cholesterol synthesis during neurite outgrowth
U Fünfschilling, WJ Jockusch, N Sivakumar, W Möbius, K Corthals, S Li, ...
Journal of Neuroscience 32 (22), 7632-7645, 2012
942012
Cholesterol and myelin biogenesis
G Saher, M Simons
Cholesterol Binding and Cholesterol Transport Proteins: Structure and …, 2010
932010
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