High cholesterol level is essential for myelin membrane growth G Saher, B Brügger, C Lappe-Siefke, W Möbius, R Tozawa, MC Wehr, ... Nature neuroscience 8 (4), 468-475, 2005 | 814 | 2005 |
Absence of integrin α7 causes a novel form of muscular dystrophy U Mayer, G Saher, R Fässler, A Bornemann, F Echtermeyer, H Mark, ... Nature genetics 17 (3), 318-323, 1997 | 565 | 1997 |
Neuropsychiatric disease relevance of circulating anti-NMDA receptor autoantibodies depends on blood–brain barrier integrity C Hammer, B Stepniak, A Schneider, S Papiol, M Tantra, M Begemann, ... Molecular psychiatry 19 (10), 1143-1149, 2014 | 386 | 2014 |
Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models R Chrast, G Saher, KA Nave, MHG Verheijen Journal of lipid research 52 (3), 419-434, 2011 | 305 | 2011 |
Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment D Paul, S Hoppe, G Saher, J Krijnse-Locker, R Bartenschlager Journal of virology 87 (19), 10612-10627, 2013 | 274 | 2013 |
The PreS2 activator MHBst of hepatitis B virus activates c‐raf‐1/Erk2 signaling in transgenic mice E Hildt, B Munz, G Saher, K Reifenberg, PH Hofschneider The EMBO journal, 2002 | 247 | 2002 |
The hepatitis B virus large surface protein (LHBs) is a transcriptional activator E Hildt, G Saher, V Bruss, PH Hofschneider Virology 225 (1), 235-239, 1996 | 222 | 1996 |
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis SA Berghoff, L Spieth, T Sun, L Hosang, L Schlaphoff, C Depp, T Düking, ... Nature neuroscience 24 (1), 47-60, 2021 | 191 | 2021 |
Cholesterol in myelin biogenesis and hypomyelinating disorders G Saher, SK Stumpf Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 184 | 2015 |
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain SA Berghoff, N Gerndt, J Winchenbach, SK Stumpf, L Hosang, F Odoardi, ... Nature communications 8 (1), 14241, 2017 | 154 | 2017 |
Cholesterol: a novel regulatory role in myelin formation G Saher, S Quintes, KA Nave The Neuroscientist 17 (1), 79-93, 2011 | 147 | 2011 |
Optimizing nervous system-specific gene targeting with Cre driver lines: prevalence of germline recombination and influencing factors L Luo, MC Ambrozkiewicz, F Benseler, C Chen, E Dumontier, S Falkner, ... Neuron 106 (1), 37-65. e5, 2020 | 144 | 2020 |
Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet G Saher, F Rudolphi, K Corthals, T Ruhwedel, KF Schmidt, S Löwel, ... Nature medicine 18 (7), 1130-1135, 2012 | 139 | 2012 |
A critical role for the cholesterol‐associated proteolipids PLP and M6B in myelination of the central nervous system HB Werner, EM Krämer‐Albers, N Strenzke, G Saher, S Tenzer, ... Glia 61 (4), 567-586, 2013 | 135 | 2013 |
Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction G Saher, S Quintes, W Möbius, MC Wehr, EM Krämer-Albers, B Brügger, ... Journal of Neuroscience 29 (19), 6094-6104, 2009 | 132 | 2009 |
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease C Depp, T Sun, AO Sasmita, L Spieth, SA Berghoff, T Nazarenko, ... Nature 618 (7964), 349-357, 2023 | 125 | 2023 |
Survival of adult neurons lacking cholesterol synthesis in vivo U Fünfschilling, G Saher, L Xiao, W Möbius, KA Nave BMC neuroscience 8, 1-9, 2007 | 106 | 2007 |
Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis K Saito, V Dubreuil, Y Arai, M Wilsch-Bräuninger, D Schwudke, G Saher, ... Proceedings of the National Academy of Sciences 106 (20), 8350-8355, 2009 | 101 | 2009 |
Critical time window of neuronal cholesterol synthesis during neurite outgrowth U Fünfschilling, WJ Jockusch, N Sivakumar, W Möbius, K Corthals, S Li, ... Journal of Neuroscience 32 (22), 7632-7645, 2012 | 94 | 2012 |
Cholesterol and myelin biogenesis G Saher, M Simons Cholesterol Binding and Cholesterol Transport Proteins: Structure and …, 2010 | 93 | 2010 |