| AU-rich elements: characterization and importance in mRNA degradation CYA Chen, AB Shyu Trends in biochemical sciences 20 (11), 465-470, 1995 | 2488 | 1995 |
| The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism R Winzen, M Kracht, B Ritter, A Wilhelm, CYA Chen, AB Shyu, M Müller, ... The EMBO journal, 1999 | 996 | 1999 |
| RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein SSY Peng, CYA Chen, N Xu, AB Shyu The EMBO journal, 1998 | 944 | 1998 |
| The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. AB Shyu, ME Greenberg, JG Belasco Genes & development 3 (1), 60-72, 1989 | 742 | 1989 |
| Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay. AB Shyu, JG Belasco, ME Greenberg Genes & development 5 (2), 221-231, 1991 | 712 | 1991 |
| Concerted action of poly (A) nucleases and decapping enzyme in mammalian mRNA turnover A Yamashita, TC Chang, Y Yamashita, W Zhu, Z Zhong, CYA Chen, ... Nature structural & molecular biology 12 (12), 1054-1063, 2005 | 677 | 2005 |
| Messenger RNA regulation: to translate or to degrade AB Shyu, MF Wilkinson, A Van Hoof The EMBO journal 27 (3), 471-481, 2008 | 573 | 2008 |
| Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation MR Fabian, G Mathonnet, T Sundermeier, H Mathys, JT Zipprich, ... Molecular cell 35 (6), 868-880, 2009 | 532 | 2009 |
| Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay N Xu, CYA Chen, AB Shyu Molecular and cellular biology, 1997 | 458 | 1997 |
| CFIm25 links alternative polyadenylation to glioblastoma tumour suppression CP Masamha, Z Xia, J Yang, TR Albrecht, M Li, AB Shyu, W Li, EJ Wagner Nature 510 (7505), 412-416, 2014 | 408 | 2014 |
| Mechanisms of deadenylation‐dependent decay CYA Chen, AB Shyu Wiley Interdisciplinary Reviews: RNA 2 (2), 167-183, 2011 | 391 | 2011 |
| Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements CYA Chen, AB Shyu Molecular and cellular biology 14 (12), 8471-8482, 1994 | 382 | 1994 |
| Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element P Loflin, CYA Chen, AB Shyu Genes & development 13 (14), 1884-1897, 1999 | 379 | 1999 |
| A mechanism for translationally coupled mRNA turnover: interaction between the poly (A) tail and a c-fos RNA coding determinant via a protein complex C Grosset, CYA Chen, N Xu, N Sonenberg, H Jacquemin-Sablon, ... Cell 103 (1), 29-40, 2000 | 372 | 2000 |
| mRNA Decay Mediated by Two Distinct AU-Rich Elements from c-fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation … CYA Chen, N Xu, AB Shyu Molecular and cellular biology 15 (10), 5777-5788, 1995 | 372 | 1995 |
| Messenger RNA half‐life measurements in mammalian cells CYA Chen, N Ezzeddine, AB Shyu Methods in enzymology 448, 335-357, 2008 | 287 | 2008 |
| The double lives of shuttling mRNA binding proteins AB Shyu, MF Wilkinson Cell 102 (2), 135-138, 2000 | 277 | 2000 |
| Ago–TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps CYA Chen, D Zheng, Z Xia, AB Shyu Nature structural & molecular biology 16 (11), 1160-1166, 2009 | 274 | 2009 |
| Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells D Zheng, N Ezzeddine, CYA Chen, W Zhu, X He, AB Shyu The Journal of cell biology 182 (1), 89-101, 2008 | 273 | 2008 |
| Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function CY Chen, TM Chen, AB Shyu Molecular and cellular biology, 1994 | 260 | 1994 |
