Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats RL Rouse, J Zhang, SR Stewart, BA Rosenzweig, P Espandiari, ... Kidney international 79 (11), 1186-1197, 2011 | 80 | 2011 |
In Utero Exposure to Environmental Tobacco Smoke Potentiates Adult Responses to Allergen in BALB/c Mice AL Penn, RL Rouse, DW Horohov, MT Kearney, DB Paulsen, L Lomax Environmental health perspectives 115 (4), 548-555, 2007 | 76 | 2007 |
Soot nanoparticles promote biotransformation, oxidative stress, and inflammation in murine lungs RL Rouse, G Murphy, MJ Boudreaux, DB Paulsen, AL Penn American journal of respiratory cell and molecular biology 39 (2), 198-207, 2008 | 75 | 2008 |
Evaluation of miR-216a and miR-217 as potential biomarkers of acute pancreatic injury in rats and mice D Goodwin, B Rosenzweig, J Zhang, L Xu, S Stewart, K Thompson, ... Biomarkers 19 (6), 517-529, 2014 | 62 | 2014 |
The effect of antibiotics on the gut microbiome: a metagenomics analysis of microbial shift and gut antibiotic resistance in antibiotic treated mice L Xu, A Surathu, I Raplee, A Chockalingam, S Stewart, L Walker, L Sacks, ... BMC genomics 21, 1-18, 2020 | 55 | 2020 |
Combustion-derived hydrocarbons localize to lipid droplets in respiratory cells G Murphy Jr, RL Rouse, WW Polk, WG Henk, SA Barker, MJ Boudreaux, ... American journal of respiratory cell and molecular biology 38 (5), 532-540, 2008 | 52 | 2008 |
Tissue and cellular distribution of gold nanoparticles varies based on aggregation/agglomeration status AM Keene, D Peters, R Rouse, S Stewart, ET Rosen, KM Tyner Nanomedicine 7 (2), 199-209, 2012 | 50 | 2012 |
Advancing biosimilar development using pharmacodynamic biomarkers in clinical pharmacology studies J Li, J Florian, E Campbell, SJ Schrieber, JPF Bai, JL Weaver, PL Hyland, ... Clinical Pharmacology and Therapeutics 107 (1), 40, 2020 | 46 | 2020 |
High fat diet and GLP-1 drugs induce pancreatic injury in mice R Rouse, L Xu, S Stewart, J Zhang Toxicology and applied pharmacology 276 (2), 104-114, 2014 | 41 | 2014 |
In Utero Environmental Tobacco Smoke Exposure Alters Gene Expression in Lungs of Adult BALB/c Mice RL Rouse, MJ Boudreaux, AL Penn Environmental health perspectives 115 (12), 1757-1766, 2007 | 40 | 2007 |
Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions JL Weaver, GA Tobin, T Ingle, S Bancos, D Stevens, R Rouse, KE Howard, ... Particle and fibre toxicology 14, 1-14, 2017 | 38 | 2017 |
Autophagy in pancreatic acinar cells in caerulein-treated mice: immunolocalization of related proteins and their potential as markers of pancreatitis L Zhang, J Zhang, K Shea, L Xu, G Tobin, A Knapton, S Sharron, R Rouse Toxicologic Pathology 42 (2), 435-457, 2014 | 38 | 2014 |
Kidney injury biomarkers in hypertensive, diabetic, and nephropathy rat models treated with contrast media RL Rouse, SR Stewart, KL Thompson, J Zhang Toxicologic pathology 41 (4), 662-680, 2013 | 35 | 2013 |
Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat R Rouse, J Siwy, W Mullen, H Mischak, J Metzger, J Hanig PLoS One 7 (4), e34606, 2012 | 34 | 2012 |
Incomplete lung recovery following sub-acute inhalation of combustion-derived ultrafine particles in mice A Noël, R Xiao, Z Perveen, HM Zaman, RL Rouse, DB Paulsen, AL Penn Particle and fibre toxicology 13, 1-20, 2015 | 32 | 2015 |
Application of mechanistic ocular absorption modeling and simulation to understand the impact of formulation properties on ophthalmic bioavailability in rabbits: a case study … M Le Merdy, J Fan, MB Bolger, V Lukacova, J Spires, E Tsakalozou, ... The AAPS Journal 21, 1-11, 2019 | 31 | 2019 |
Histopathology and pathogenesis of caerulein-, duct ligation-, and arginine-induced acute pancreatitis in Sprague-Dawley rats and C57BL6 mice J Zhang, RL Rouse F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de …, 2014 | 31 | 2014 |
Effect of oral ranitidine on urinary excretion of N-nitrosodimethylamine (NDMA): a randomized clinical trial J Florian, MK Matta, R DePalma, V Gershuny, V Patel, CH Hsiao, ... Jama 326 (3), 240-249, 2021 | 29 | 2021 |
Translating new science into the drug review process: the US FDA’s Division of Applied Regulatory Science R Rouse, N Kruhlak, J Weaver, K Burkhart, V Patel, DG Strauss Therapeutic innovation & regulatory science 52 (2), 244-255, 2018 | 27 | 2018 |
In utero exposure to second-hand smoke aggravates the response to ovalbumin in adult mice R Xiao, Z Perveen, RL Rouse, V Le Donne, DB Paulsen, N Ambalavanan, ... American journal of respiratory cell and molecular biology 49 (6), 1102-1109, 2013 | 27 | 2013 |