Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing LM Lim, N Ly, D Anderson, JC Yang, L Macander, A Jarkowski III, ... Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 30 (12 …, 2010 | 563 | 2010 |
Attenuation of Colistin Bactericidal Activity by High Inoculum of Pseudomonas aeruginosa Characterized by a New Mechanism-Based Population … JB Bulitta, JC Yang, L Yohonn, NS Ly, SV Brown, RE D'Hondt, WJ Jusko, ... Antimicrobial agents and chemotherapy 54 (5), 2051-2062, 2010 | 151 | 2010 |
Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa JB Bulitta, NS Ly, JC Yang, A Forrest, WJ Jusko, BT Tsuji Antimicrobial agents and chemotherapy 53 (1), 46-56, 2009 | 111 | 2009 |
Two mechanisms of killing of Pseudomonas aeruginosa by tobramycin assessed at multiple inocula via mechanism-based modeling JB Bulitta, NS Ly, CB Landersdorfer, NA Wanigaratne, T Velkov, R Yadav, ... Antimicrobial agents and chemotherapy 59 (4), 2315-2327, 2015 | 104 | 2015 |
Quantifying subpopulation synergy for antibiotic combinations via mechanism-based modeling and a sequential dosing design CB Landersdorfer, NS Ly, H Xu, BT Tsuji, JB Bulitta Antimicrobial Agents and Chemotherapy, 2013 | 84 | 2013 |
Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance NS Ly, JB Bulitta, GG Rao, CB Landersdorfer, PN Holden, A Forrest, ... Journal of antimicrobial chemotherapy 70 (5), 1434-1442, 2015 | 81 | 2015 |
Polymyxin B in combination with meropenem against carbapenemase-producing Klebsiella pneumoniae: pharmacodynamics and morphological changes R Sharma, S Patel, C Abboud, J Diep, NS Ly, JM Pogue, KS Kaye, J Li, ... International journal of antimicrobial agents 49 (2), 224-232, 2017 | 56 | 2017 |
Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies GG Rao, NS Ly, JB Bulitta, RL Soon, MD San Roman, PN Holden, ... Journal of Antimicrobial Chemotherapy 71 (11), 3148-3156, 2016 | 42 | 2016 |
New dosing strategies for an old antibiotic: pharmacodynamics of front-loaded regimens of colistin at simulated pharmacokinetics in patients with kidney or liver disease GG Rao, NS Ly, CE Haas, S Garonzik, A Forrest, JB Bulitta, PA Kelchlin, ... Antimicrobial agents and chemotherapy 58 (3), 1381-1388, 2014 | 41 | 2014 |
Impact of two-component regulatory systems PhoP-PhoQ and PmrA-PmrB on colistin pharmacodynamics in Pseudomonas aeruginosa NS Ly, J Yang, JB Bulitta, BT Tsuji Antimicrobial agents and chemotherapy 56 (6), 3453-3456, 2012 | 36 | 2012 |
Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii GG Rao, NS Ly, J Diep, A Forrest, JB Bulitta, PN Holden, RL Nation, J Li, ... International journal of antimicrobial agents 48 (3), 331-336, 2016 | 34 | 2016 |
Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses B Chen, KA Vousden, B Naiman, S Turman, H Sun, S Wang, LMK Vinall, ... Annals of the rheumatic diseases 78 (2), 228-237, 2019 | 30 | 2019 |
Optimization of polymyxin B in combination with doripenem to combat mutator Pseudomonas aeruginosa NS Ly, ZP Bulman, JB Bulitta, C Baron, GG Rao, PN Holden, J Li, ... Antimicrobial agents and chemotherapy 60 (5), 2870-2880, 2016 | 28 | 2016 |
Moving from point‐based analysis to systems‐based modeling: integration of knowledge to address antimicrobial resistance against MDR bacteria E Garcia, N Ly, JK Diep, GG Rao Clinical Pharmacology & Therapeutics 110 (5), 1196-1206, 2021 | 21 | 2021 |
Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin ZP Bulman, NS Ly, JR Lenhard, PN Holden, JB Bulitta, BT Tsuji Antimicrobial Agents and Chemotherapy 61 (4), 10.1128/aac. 00096-16, 2017 | 19 | 2017 |
Population pharmacokinetics and target attainment of ertapenem in plasma and tissue assessed via microdialysis in morbidly obese patients after laparoscopic visceral surgery M Wittau, S Paschke, M Kurlbaum, J Scheele, NS Ly, E Hemper, ... Antimicrobial Agents and Chemotherapy 61 (1), 10.1128/aac. 00952-16, 2017 | 16 | 2017 |
Systems pharmacology and pharmacodynamics DE Mager, HHC Kimko Springer, 2016 | 16 | 2016 |
Pharmacokinetic and pharmacodynamic modeling of tezepelumab to guide phase 3 dose selection for patients with severe asthma N Ly, Y Zheng, JM Griffiths, R van der Merwe, B Agoram, JR Parnes, ... The Journal of Clinical Pharmacology 61 (7), 901-912, 2021 | 14 | 2021 |
Pharmacodynamic variability beyond that explained by MICs RL Soon, NS Ly, G Rao, L Wollenberg, K Yang, B Tsuji, A Forrest Antimicrobial agents and chemotherapy 57 (4), 1730-1735, 2013 | 12 | 2013 |
Population pharmacokinetics of cotadutide in subjects with type 2 diabetes Y Guan, N Ly, J Li, RH Arends Clinical Pharmacokinetics 61 (6), 833-845, 2022 | 9 | 2022 |