| Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer M Hornburg, M Desbois, S Lu, Y Guan, AA Lo, S Kaufman, A Elrod, ... Cancer cell 39 (7), 928-944. e6, 2021 | 186 | 2021 |
| Bioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicity TM DesRochers, L Suter, A Roth, DL Kaplan PloS one 8 (3), e59219, 2013 | 163 | 2013 |
| Tissue-engineered kidney disease models TM DesRochers, E Palma, DL Kaplan Advanced drug delivery reviews 69, 67-80, 2014 | 122 | 2014 |
| The effect of sterilization on silk fibroin biomaterial properties J Rnjak‐Kovacina, TM DesRochers, KA Burke, DL Kaplan Macromolecular bioscience 15 (6), 861-874, 2015 | 96 | 2015 |
| The influence of specific binding of collagen–silk chimeras to silk biomaterials on hMSC behavior B An, TM DesRochers, G Qin, X Xia, G Thiagarajan, B Brodsky, ... Biomaterials 34 (2), 402-412, 2013 | 75 | 2013 |
| Prospective Validation of an Ex Vivo, Patient-Derived 3D Spheroid Model for Response Predictions in Newly Diagnosed Ovarian Cancer S Shuford, C Wilhelm, M Rayner, A Elrod, M Millard, C Mattingly, ... Scientific reports 9 (1), 11153, 2019 | 60 | 2019 |
| E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents A Alt-Holland, Y Shamis, KN Riley, TM DesRochers, NE Fusenig, ... Journal of investigative dermatology 128 (10), 2498-2507, 2008 | 52 | 2008 |
| Cyst formation following disruption of intracellular calcium signaling IY Kuo, TM DesRochers, EP Kimmerling, L Nguyen, BE Ehrlich, ... Proceedings of the National Academy of Sciences 111 (39), 14283-14288, 2014 | 49 | 2014 |
| The 3D tissue microenvironment modulates DNA methylation and E-cadherin expression in squamous cell carcinoma TM DesRochers, Y Shamis, A Alt-Holland, Y Kudo, T Takata, G Wang, ... Epigenetics 7 (1), 34-46, 2012 | 42 | 2012 |
| The regulation of cystogenesis in a tissue engineered kidney disease system by abnormal matrix interactions B Subramanian, WC Ko, V Yadav, TM DesRochers, RD Perrone, J Zhou, ... Biomaterials 33 (33), 8383-8394, 2012 | 35 | 2012 |
| Effects of Shiga toxin type 2 on a bioengineered three-dimensional model of human renal tissue TM DesRochers, EP Kimmerling, DM Jandhyala, W El-Jouni, J Zhou, ... Infection and Immunity 83 (1), 28-38, 2015 | 25 | 2015 |
| PD-1/PD-L1 checkpoint inhibitors in combination with olaparib display antitumor activity in ovarian cancer patient-derived three-dimensional spheroid cultures KM Appleton, AK Elrod, KA Lassahn, S Shuford, LM Holmes, ... Cancer Immunology, Immunotherapy 70 (3), 843-856, 2021 | 21 | 2021 |
| 3D Tissue Culture Devices and Systems DE Orr, MR Gevaert, C Cheluvaraju, HE Crosswell, TM DesRochers US Patent App. 14/637,383, 2015 | 21 | 2015 |
| Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay S Shuford, L Lipinski, A Abad, AM Smith, M Rayner, L O’Donnell, J Stuart, ... Neuro-Oncology Advances 3 (1), vdab065, 2021 | 17 | 2021 |
| A functional precision medicine pipeline combines comparative transcriptomics and tumor organoid modeling to identify bespoke treatment strategies for glioblastoma MR Reed, AG Lyle, A De Loose, L Maddukuri, K Learned, HC Beale, ... Cells 10 (12), 3400, 2021 | 16 | 2021 |
| The effects of mycoplasma contamination upon the ability to form bioengineered 3D kidney cysts TM DesRochers, IY Kuo, EP Kimmerling, BE Ehrlich, DL Kaplan PloS one 10 (3), e0120097, 2015 | 10 | 2015 |
| Macrophage incorporation into a 3D perfusion tri-culture model of human breast cancer TM DesRochers, L Holmes, L O'Donnell, C Mattingly, S Shuford, ... Journal for Immunotherapy of cancer 3 (Suppl 2), P401, 2015 | 7 | 2015 |
| Preclinical testing of therapeutic biologics using patient-derived 3D spheroids KA Lassahn, AK Elrod, AL Carlson, NA Dance, M Millard, MJ Wick, ... Cancer Research 83 (7_Supplement), 2275-2275, 2023 | 2 | 2023 |
| Dissecting personalized PD-1 inhibitor efficacy using patient-derived 3D spheroids KM Appleton, KA Lassahn, AK Elrod, TM DesRochers Cancer Research 82 (12_Supplement), 4162-4162, 2022 | 2 | 2022 |
| Bio-engineered human kidney for the study of nephrotoxicity and kidney disease TM DesRochers, W Ko, B Subramanian, R Perrone, JV Shah, DL Kaplan JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 6, 126-126, 2012 | 2 | 2012 |
