Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals F Ichas, LS Jouaville, JP Mazat Cell 89 (7), 1145-1153, 1997 | 898 | 1997 |
From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low-to high-conductance state F Ichas, JP Mazat Biochimica et Biophysica Acta (BBA)-Bioenergetics 1366 (1-2), 33-50, 1998 | 769 | 1998 |
Spatial relational memory requires hippocampal adult neurogenesis D Dupret, JM Revest, M Koehl, F Ichas, F De Giorgi, P Costet, DN Abrous, ... PloS one 3 (4), e1959, 2008 | 737 | 2008 |
Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes LS Jouaville, F Ichas, EL Holmuhamedov, P Camacho, JD Lechleiter Nature 377 (6548), 438-441, 1995 | 521 | 1995 |
Regulation of the permeability transition pore in skeletal muscle mitochondria: modulation by electron flow through the respiratory chain complex I E Fontaine, O Eriksson, F Ichas, P Bernardi Journal of Biological Chemistry 273 (20), 12662-12668, 1998 | 416 | 1998 |
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization F De Giorgi, L Lartigue, MKA Bauer, A Schubert, S Grimm, GT Hanson, ... The FASEB journal 16 (6), 607-609, 2002 | 336 | 2002 |
A ubiquinone-binding site regulates the mitochondrial permeability transition pore E Fontaine, F Ichas, P Bernardi Journal of Biological Chemistry 273 (40), 25734-25740, 1998 | 324 | 1998 |
Oligomeric Bax Is a Component of the Putative Cytochrome c Release Channel MAC, Mitochondrial Apoptosis-induced Channel LM Dejean, S Martinez-Caballero, L Guo, C Hughes, O Teijido, T Ducret, ... Molecular biology of the cell 16 (5), 2424-2432, 2005 | 320 | 2005 |
Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion NL Benali-Furet, M Chami, L Houel, F De Giorgi, F Vernejoul, D Lagorce, ... Oncogene 24 (31), 4921-4933, 2005 | 319 | 2005 |
The mitochondrial permeability transition P Bernardi, R Colonna, P Costantini, O Eriksson, E Fontaine, F Ichas, ... Biofactors 8 (3‐4), 273-281, 1998 | 213 | 1998 |
Mitochondrial calcium spiking: a transduction mechanism based on calcium‐induced permeability transition involved in cell calcium signalling F Ichas, LS Jouaville, SS Sidash, JP Mazat, EL Holmuhamedov FEBS letters 348 (2), 211-215, 1994 | 171 | 1994 |
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates F Laferrière, Z Maniecka, M Pérez-Berlanga, M Hruska-Plochan, ... Nature neuroscience 22 (1), 65-77, 2019 | 154 | 2019 |
Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis F Tomasello, A Messina, L Lartigue, L Schembri, C Medina, S Reina, ... Cell research 19 (12), 1363-1376, 2009 | 151 | 2009 |
Electrical coupling and plasticity of the mitochondrial network F De Giorgi, L Lartigue, F Ichas Cell calcium 28 (5-6), 365-370, 2000 | 145 | 2000 |
In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains F Cavaliere, L Cerf, B Dehay, P Ramos-Gonzalez, F De Giorgi, ... Neurobiology of disease 103, 101-112, 2017 | 118 | 2017 |
Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases? J Dessolin, M Schuler, A Quinart, F De Giorgi, L Ghosez, F Ichas European journal of pharmacology 447 (2-3), 155-161, 2002 | 101 | 2002 |
Label-free optical imaging of mitochondria in live cells D Lasne, GA Blab, F De Giorgi, F Ichas, B Lounis, L Cognet Optics express 15 (21), 14184-14193, 2007 | 98 | 2007 |
Effects of the anaesthetic propofol on the calcium-induced permeability transition of rat heart mitochondria: direct pore inhibition and shift of the gating potential F Sztark, F Ichas, R Ouhabi, P Dabadie, JP Mazat FEBS letters 368 (1), 101-104, 1995 | 98 | 1995 |
Microtubule-active drugs suppress the closure of the permeability transition pore in tumour mitochondria YV Evtodienko, VV Teplova, SS Sidash, F Ichas, JP Mazat FEBS letters 393 (1), 86-88, 1996 | 91 | 1996 |
New functions of an old protein: the eukaryotic porin or voltage dependent anion selective channel (VDAC) V De Pinto, A Messina, R Accardi, R Aiello, F Guarino, MF Tomasello, ... Italian Journal of Biochemistry 52 (1), 17-24, 2003 | 90 | 2003 |