| A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans GL Bond, W Hu, EE Bond, H Robins, SG Lutzker, NC Arva, J Bargonetti, ... Cell 119 (5), 591-602, 2004 | 1482 | 2004 |
| The genetics of the p53 pathway, apoptosis and cancer therapy A Vazquez, EE Bond, AJ Levine, GL Bond Nature reviews Drug discovery 7 (12), 979-987, 2008 | 876 | 2008 |
| MDM2 is a central node in the p53 pathway: 12 years and counting GL Bond, W Hu, AJ Levine Current cancer drug targets 5 (1), 3-8, 2005 | 396 | 2005 |
| MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner GL Bond, KM Hirshfield, T Kirchhoff, G Alexe, EE Bond, H Robins, F Bartel, ... Cancer research 66 (10), 5104-5110, 2006 | 357 | 2006 |
| A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect GL Bond, W Hu, A Levine Cancer research 65 (13), 5481-5484, 2005 | 239 | 2005 |
| A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans GL Bond, AJ Levine Oncogene 26 (9), 1317-1323, 2007 | 215 | 2007 |
| The importance of p53 pathway genetics in inherited and somatic cancer genomes G Stracquadanio, X Wang, MD Wallace, AM Grawenda, P Zhang, J Hewitt, ... Nature reviews Cancer 16 (4), 251-265, 2016 | 166 | 2016 |
| A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells NC Arva, TR Gopen, KE Talbott, LE Campbell, A Chicas, DE White, ... Journal of Biological Chemistry 280 (29), 26776-26787, 2005 | 152 | 2005 |
| Identification and functional characterization of neo-poly (A) polymerase, an RNA processing enzyme overexpressed in human tumors SL Topalian, S Kaneko, MI Gonzales, GL Bond, Y Ward, JL Manley Molecular and cellular biology, 2001 | 148 | 2001 |
| A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection J Zeron-Medina, X Wang, E Repapi, MR Campbell, D Su, F Castro-Giner, ... Cell 155 (2), 410-422, 2013 | 132 | 2013 |
| A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development SM Post, A Quintás-Cardama, V Pant, T Iwakuma, A Hamir, JG Jackson, ... Cancer cell 18 (3), 220-230, 2010 | 122 | 2010 |
| MDM2 SNP309 accelerates colorectal tumour formation in women GL Bond, C Menin, R Bertorelle, P Alhopuro, LA Aaltonen, AJ Levine Journal of medical genetics 43 (12), 950-952, 2006 | 121 | 2006 |
| Single-nucleotide polymorphisms in the p53 signaling pathway LF Grochola, J Zeron-Medina, S Mériaux, GL Bond Cold Spring Harbor perspectives in biology 2 (5), a001032, 2010 | 119 | 2010 |
| Detection of functional single-nucleotide polymorphisms that affect apoptosis SL Harris, G Gil, H Robins, W Hu, K Hirshfield, E Bond, G Bond, AJ Levine Proceedings of the National Academy of Sciences 102 (45), 16297-16302, 2005 | 91 | 2005 |
| MEF2 transcription factors are key regulators of sprouting angiogenesis N Sacilotto, KM Chouliaras, LL Nikitenko, YW Lu, M Fritzsche, ... Genes & development 30 (20), 2297-2309, 2016 | 90 | 2016 |
| Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice B Leroy, ML Ballinger, F Baran-Marszak, GL Bond, A Braithwaite, ... Cancer research 77 (6), 1250-1260, 2017 | 89 | 2017 |
| Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene GS Atwal, T Kirchhoff, EE Bond, M Montagna, C Menin, R Bertorelle, ... Proceedings of the National Academy of Sciences 106 (25), 10236-10241, 2009 | 79 | 2009 |
| Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer K Lenos, AM Grawenda, K Lodder, ML Kuijjer, AFAS Teunisse, E Repapi, ... Cancer research 72 (16), 4074-4084, 2012 | 75 | 2012 |
| Haplotype structure and selection of the MDM2 oncogene in humans GS Atwal, GL Bond, S Metsuyanim, M Papa, E Friedman, ... Proceedings of the National Academy of Sciences 104 (11), 4524-4529, 2007 | 70 | 2007 |
| Venous identity requires BMP signalling through ALK3 A Neal, S Nornes, S Payne, MD Wallace, M Fritzsche, P Louphrasitthiphol, ... Nature communications 10 (1), 453, 2019 | 66 | 2019 |
