Crystal structure of the β2 adrenergic receptor–Gs protein complex SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ... Nature 477 (7366), 549-555, 2011 | 3488 | 2011 |
Conformational changes in the G protein Gs induced by the [bgr] 2 adrenergic receptor KY Chung, SGF Rasmussen, T Liu, S Li, BT DeVree, PS Chae, D Calinski, ... Nature 477 (7366), 611-615, 2011 | 440 | 2011 |
Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex GH Westfield, SGF Rasmussen, M Su, S Dutta, BT DeVree, KY Chung, ... Proceedings of the National Academy of Sciences 108 (38), 16086-16091, 2011 | 280 | 2011 |
The role of ligands on the equilibria between functional states of a G protein-coupled receptor TH Kim, KY Chung, A Manglik, AL Hansen, RO Dror, TJ Mildorf, DE Shaw, ... Journal of the American Chemical Society 135 (25), 9465-9474, 2013 | 202 | 2013 |
Assembly of a GPCR-G protein complex Y Du, NM Duc, SGF Rasmussen, D Hilger, X Kubiak, L Wang, J Bohon, ... Cell 177 (5), 1232-1242. e11, 2019 | 194 | 2019 |
Structural and functional analysis of a β2-adrenergic receptor complex with GRK5 KE Komolov, Y Du, NM Duc, RM Betz, JP Rodrigues, RD Leib, D Patra, ... Cell 169 (3), 407-421. e16, 2017 | 159 | 2017 |
Role of detergents in conformational exchange of a G protein-coupled receptor KY Chung, TH Kim, A Manglik, R Alvares, BK Kobilka, RS Prosser Journal of Biological Chemistry 287 (43), 36305-36311, 2012 | 118 | 2012 |
Structural mechanism of G protein activation by G protein-coupled receptor NM Duc, HR Kim, KY Chung European journal of pharmacology 763, 214-222, 2015 | 116 | 2015 |
Orthosteric and allosteric action of the C5a receptor antagonists H Liu, HR Kim, RNVK Deepak, L Wang, KY Chung, H Fan, Z Wei, ... Nature structural & molecular biology 25 (6), 472-481, 2018 | 114 | 2018 |
Gq activity-and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility DL Zhang, YJ Sun, ML Ma, Y Wang, H Lin, RR Li, ZL Liang, Y Gao, ... Elife 7, e33432, 2018 | 87 | 2018 |
Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase S Jang, C Kang, HS Yang, T Jung, H Hebert, KY Chung, SJ Kim, S Hohng, ... Genes & development 33 (11-12), 620-625, 2019 | 80 | 2019 |
Novel antiplatelet activity of protocatechuic acid through the inhibition of high shear stress-induced platelet aggregation K Kim, ON Bae, KM Lim, JY Noh, S Kang, KY Chung, JH Chung Journal of Pharmacology and Experimental Therapeutics 343 (3), 704-711, 2012 | 66 | 2012 |
Conformational sensors and domain swapping reveal structural and functional differences between β-arrestin isoforms E Ghosh, H Dwivedi, M Baidya, A Srivastava, P Kumari, T Stepniewski, ... Cell Reports 28 (13), 3287-3299. e6, 2019 | 62 | 2019 |
G-protein coupled receptor signaling in myocardium: not for the faint of heart M Kang, KY Chung, JW Walker Physiology 22 (3), 174-184, 2007 | 60 | 2007 |
Effective application of bicelles for conformational analysis of G protein-coupled receptors by hydrogen/deuterium exchange mass spectrometry NM Duc, Y Du, TS Thorsen, SY Lee, C Zhang, H Kato, BK Kobilka, ... Journal of the American Society for Mass Spectrometry 26 (5), 808-817, 2015 | 57 | 2015 |
Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family HR Kim, J Xu, S Maeda, NM Duc, D Ahn, Y Du, KY Chung Nature Communications 11 (1), 3160, 2020 | 54 | 2020 |
Crystal structure of β-arrestin 2 in complex with CXCR7 phosphopeptide K Min, HJ Yoon, JY Park, M Baidya, H Dwivedi-Agnihotri, J Maharana, ... Structure 28 (9), 1014-1023. e4, 2020 | 49 | 2020 |
Structural mechanism of GPCR-arrestin interaction: recent breakthroughs JY Park, SY Lee, HR Kim, MD Seo, KY Chung Archives of pharmacal research 39, 293-301, 2016 | 45 | 2016 |
Biophysical and functional characterization of Norrin signaling through Frizzled4 I Bang, HR Kim, AH Beaven, J Kim, SB Ko, GR Lee, W Kan, H Lee, W Im, ... Proceedings of the National Academy of Sciences 115 (35), 8787-8792, 2018 | 43 | 2018 |
Calcitonin receptor N-glycosylation enhances peptide hormone affinity by controlling receptor dynamics SM Lee, Y Jeong, J Simms, ML Warner, DR Poyner, KY Chung, ... Journal of molecular biology 432 (7), 1996-2014, 2020 | 39 | 2020 |