| Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria P Pasinelli, ME Belford, N Lennon, BJ Bacskai, BT Hyman, D Trotti, ... Neuron 43 (1), 19-30, 2004 | 640 | 2004 |
| Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes A Volterra, D Trotti, C Tromba, S Floridi, G Racagni Journal of Neuroscience 14 (5), 2924-2932, 1994 | 605 | 1994 |
| Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? D Trotti, NC Danbolt, A Volterra Trends in pharmacological sciences 19 (8), 328-334, 1998 | 595 | 1998 |
| Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... Neuron 84 (6), 1213-1225, 2014 | 566 | 2014 |
| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 557 | 2018 |
| SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter D Trotti, A Rolfs, NC Danbolt, RH Brown, MA Hediger Nature neuroscience 2 (5), 427-433, 1999 | 479 | 1999 |
| Peroxynitrite Inhibits Glutamate Transporter Subtypes (∗) D Trotti, D Rossi, O Gjesdal, LM Levy, G Racagni, NC Danbolt, A Volterra Journal of Biological Chemistry 271 (11), 5976-5979, 1996 | 356 | 1996 |
| Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis E Foran, D Trotti Antioxidants & redox signaling 11 (7), 1587-1602, 2009 | 347 | 2009 |
| Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders H Qosa, DS Miller, P Pasinelli, D Trotti Brain research 1628, 298-316, 2015 | 242 | 2015 |
| High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes A Volterra, D Trotti, P Cassutti, C Tromba, A Salvaggio, RC Melcangi, ... Journal of neurochemistry 59 (2), 600-606, 1992 | 224 | 1992 |
| Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity D Trotti, M Aoki, P Pasinelli, UV Berger, NC Danbolt, RH Brown, ... Journal of Biological Chemistry 276 (1), 576-582, 2001 | 223 | 2001 |
| Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ... Cell reports 17 (3), 645-652, 2016 | 222 | 2016 |
| Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. A Volterra, D Trotti, G Racagni Molecular pharmacology 46 (5), 986-992, 1994 | 209 | 1994 |
| Neuronal and glial glutamate transporters possess an SH‐based redox regulatory mechanism D Trotti, BL Rizzini, D Rossi, O Haugeto, G Racagni, NC Danbolt, ... European Journal of Neuroscience 9 (6), 1236-1243, 1997 | 203 | 1997 |
| An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1 S Guareschi, E Cova, C Cereda, M Ceroni, E Donetti, DA Bosco, D Trotti, ... Proceedings of the National Academy of Sciences 109 (13), 5074-5079, 2012 | 198 | 2012 |
| Caspase-3 cleaves and inactivates the glutamate transporter EAAT2 W Boston-Howes, SL Gibb, EO Williams, P Pasinelli, RH Brown, D Trotti Journal of Biological Chemistry 281 (20), 14076-14084, 2006 | 183 | 2006 |
| ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2 S Pedrini, D Sau, S Guareschi, M Bogush, RH Brown Jr, N Naniche, A Kia, ... Human molecular genetics 19 (15), 2974-2986, 2010 | 169 | 2010 |
| Regulation of glutamate transporters in health and disease G Gegelashvili, MB Robinson, D Trotti, T Rauen Progress in Brain Research 132, 267-286, 2001 | 148 | 2001 |
| Arachidonic Acid Inhibits a Purified and Reconstituted Glutamate Transporter Directly from the Water Phase and Not via the Phospholipid Membrane (∗) D Trotti, A Volterra, KP Lehre, D Rossi, O Gjesdal, G Racagni, NC Danbolt Journal of Biological Chemistry 270 (17), 9890-9895, 1995 | 142 | 1995 |
| Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis M Castagna, C Shayakul, D Trotti, VF Sacchi, WR Harvey, MA Hediger Journal of Experimental Biology 200 (2), 269-286, 1997 | 138 | 1997 |
