The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure A Kennedy, TW Gettys, P Watson, P Wallace, E Ganaway, QIN Pan, ... The Journal of Clinical Endocrinology & Metabolism 82 (4), 1293-1300, 1997 | 685 | 1997 |
Multiplicity of mechanisms of serotonin receptor signal transduction JR Raymond, YV Mukhin, A Gelasco, J Turner, G Collinsworth, TW Gettys, ... Pharmacology & therapeutics 92 (2-3), 179-212, 2001 | 632 | 2001 |
FGF21 is an endocrine signal of protein restriction T Laeger, TM Henagan, DC Albarado, LM Redman, GA Bray, RC Noland, ... The Journal of clinical investigation 124 (9), 3913-3922, 2014 | 553 | 2014 |
The metabolism and significance of homocysteine in nutrition and health A Kumar, HA Palfrey, R Pathak, PJ Kadowitz, TW Gettys, SN Murthy Nutrition & metabolism 14, 1-12, 2017 | 349 | 2017 |
The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes TW Gettys, PJ Harkness, PM Watson Endocrinology 137 (9), 4054-4057, 1996 | 349 | 1996 |
The recombinant 5‐HT1A receptor: G protein coupling and signalling pathways JR Raymond, YV Mukhin, TW Gettys, MN Garnovskaya British journal of pharmacology 127 (8), 1751-1764, 1999 | 306 | 1999 |
Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet LK Stewart, JL Soileau, D Ribnicky, ZQ Wang, I Raskin, A Poulev, ... Metabolism 57, S39-S46, 2008 | 275 | 2008 |
Impaired expression and functional activity of the beta 3-and beta 1-adrenergic receptors in adipose tissue of congenitally obese (C57BL/6J ob/ob) mice. S Collins, KW Daniel, EM Rohlfs, V Ramkumar, IL Taylor, TW Gettys Molecular endocrinology 8 (4), 518-527, 1994 | 266 | 1994 |
Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states BE Hasek, LK Stewart, TM Henagan, A Boudreau, NR Lenard, C Black, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 243 | 2010 |
Induction of uncoupling protein expression in brown and white adipose tissue by leptin SP Commins, PM Watson, MA Padgett, A Dudley, G Argyropoulos, ... Endocrinology 140 (1), 292-300, 1999 | 236 | 1999 |
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21 EK Lees, E Król, L Grant, K Shearer, C Wyse, E Moncur, AS Bykowska, ... Aging cell 13 (5), 817-827, 2014 | 203 | 2014 |
Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice KP Stone, D Wanders, M Orgeron, CC Cortez, TW Gettys Diabetes 63 (11), 3721-3733, 2014 | 194 | 2014 |
Dietary methionine restriction increases fat oxidation in obese adults with metabolic syndrome EP Plaisance, FL Greenway, A Boudreau, KL Hill, WD Johnson, ... The Journal of Clinical Endocrinology & Metabolism 96 (5), E836-E840, 2011 | 184 | 2011 |
Metabolic responses to dietary protein restriction require an increase in FGF21 that is delayed by the absence of GCN2 T Laeger, DC Albarado, SJ Burke, L Trosclair, JW Hedgepeth, ... Cell reports 16 (3), 707-716, 2016 | 181 | 2016 |
Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1α Y Zhang, P Huypens, AW Adamson, JS Chang, TM Henagan, A Boudreau, ... Journal of Biological Chemistry 284 (47), 32813-32826, 2009 | 174 | 2009 |
Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor TM Palmer, TW Gettys, GL Stiles Journal of Biological Chemistry 270 (28), 16895-16902, 1995 | 174 | 1995 |
Cell-specific physical and functional coupling of human 5-HT1A receptors to inhibitory G protein. alpha.-subunits and lack of coupling to Gs. alpha. JR Raymond, CL Olsen, TW Gettys Biochemistry 32 (41), 11064-11073, 1993 | 174 | 1993 |
Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats G Suchankova, M Tekle, AK Saha, NB Ruderman, SD Clarke, TW Gettys Biochemical and biophysical research communications 326 (4), 851-858, 2005 | 161 | 2005 |
Role of GCN2-independent signaling through a noncanonical PERK/NRF2 pathway in the physiological responses to dietary methionine restriction D Wanders, KP Stone, LA Forney, CC Cortez, KN Dille, J Simon, M Xu, ... Diabetes 65 (6), 1499-1510, 2016 | 146 | 2016 |
Central leptin regulates the UCP1 and obGenes in brown and white adipose tissue via different β-adrenoceptor subtypes SP Commins, PM Watson, N Levin, RJ Beiler, TW Gettys Journal of Biological Chemistry 275 (42), 33059-33067, 2000 | 139 | 2000 |