Trolox attenuates mechanical ventilation–induced diaphragmatic dysfunction and proteolysis JL Betters, DS Criswell, RA Shanely, D Van Gammeren, D Falk, ... American journal of respiratory and critical care medicine 170 (11), 1179-1184, 2004 | 245 | 2004 |
Caspase-3 regulation of diaphragm myonuclear domain during mechanical ventilation–induced atrophy JM McClung, AN Kavazis, KC DeRuisseau, DJ Falk, MA Deering, Y Lee, ... American journal of respiratory and critical care medicine 175 (2), 150-159, 2007 | 209 | 2007 |
Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition JP French, JC Quindry, DJ Falk, JL Staib, Y Lee, KKW Wang, SK Powers American Journal of Physiology-Heart and Circulatory Physiology 290 (1 …, 2006 | 202 | 2006 |
Antioxidant administration attenuates mechanical ventilation‐induced rat diaphragm muscle atrophy independent of protein kinase B (PKB–Akt) signalling JM McClung, AN Kavazis, MA Whidden, KC DeRuisseau, DJ Falk, ... The Journal of physiology 585 (1), 203-215, 2007 | 162 | 2007 |
Mechanical ventilation induces alterations of the ubiquitin-proteasome pathway in the diaphragm KC DeRuisseau, AN Kavazis, MA Deering, DJ Falk, D Van Gammeren, ... Journal of applied physiology 98 (4), 1314-1321, 2005 | 143 | 2005 |
Characterization of a transgenic short hairpin RNA-induced murine model of Tafazzin deficiency MS Soustek, DJ Falk, CS Mah, MJ Toth, M Schlame, AS Lewin, BJ Byrne Human gene therapy 22 (7), 865-871, 2011 | 130 | 2011 |
The respiratory neuromuscular system in Pompe disease DD Fuller, MK ElMallah, BK Smith, M Corti, LA Lawson, DJ Falk, BJ Byrne Respiratory physiology & neurobiology 189 (2), 241-249, 2013 | 126 | 2013 |
B-cell depletion is protective against anti-AAV capsid immune response: a human subject case study M Corti, ME Elder, DJ Falk, L Lawson, BK Smith, S Nayak, TJ Conlon, ... Molecular Therapy-Methods & Clinical Development 1, 2014 | 123 | 2014 |
Pompe disease gene therapy BJ Byrne, DJ Falk, CA Pacak, S Nayak, RW Herzog, ME Elder, SW Collins, ... Human molecular genetics 20 (R1), R61-R68, 2011 | 123 | 2011 |
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction MA Whidden, JM McClung, DJ Falk, MB Hudson, AJ Smuder, WB Nelson, ... Journal of applied physiology 106 (2), 385-394, 2009 | 123 | 2009 |
Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation JM McClung, D Van Gammeren, MA Whidden, DJ Falk, AN Kavazis, ... Critical care medicine 37 (4), 1373-1379, 2009 | 106 | 2009 |
Mechanical ventilation promotes redox status alterations in the diaphragm DJ Falk, KC DeRuisseau, DL Van Gammeren, MA Deering, AN Kavazis, ... Journal of applied physiology 101 (4), 1017-1024, 2006 | 106 | 2006 |
Sustained correction of motoneuron histopathology following intramuscular delivery of AAV in pompe mice MK ElMallah, DJ Falk, S Nayak, RA Federico, MS Sandhu, A Poirier, ... Molecular Therapy 22 (4), 702-712, 2014 | 93 | 2014 |
Peripheral nerve and neuromuscular junction pathology in Pompe disease DJ Falk, AG Todd, S Lee, MS Soustek, MK ElMallah, DD Fuller, ... Human molecular genetics 24 (3), 625-636, 2015 | 88 | 2015 |
Redox regulation of diaphragm proteolysis during mechanical ventilation JM McClung, MA Whidden, AN Kavazis, DJ Falk, KC DeRuisseau, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008 | 88 | 2008 |
Gel-mediated delivery of AAV1 vectors corrects ventilatory function in Pompe mice with established disease CS Mah, DJ Falk, SA Germain, JS Kelley, MA Lewis, DA Cloutier, ... Molecular Therapy 18 (3), 502-510, 2010 | 86 | 2010 |
Intrapleural administration of AAV9 improves neural and cardiorespiratory function in Pompe disease DJ Falk, CS Mah, MS Soustek, KZ Lee, MK ElMallah, DA Cloutier, ... Molecular Therapy 21 (9), 1661-1667, 2013 | 73 | 2013 |
Comparative impact of AAV and enzyme replacement therapy on respiratory and cardiac function in adult Pompe mice DJ Falk, MS Soustek, AG Todd, CS Mah, DA Cloutier, JS Kelley, ... Molecular therapy Methods & clinical development 2, 2015 | 69 | 2015 |
Gene therapy approaches for lysosomal storage disease: next-generation treatment BJ Byrne, DJ Falk, N Clément, CS Mah Human gene therapy 23 (8), 808-815, 2012 | 65 | 2012 |
Correcting N euromuscular D eficits W ith G ene T herapy in P ompe D isease AG Todd, JA McElroy, RW Grange, DD Fuller, GA Walter, BJ Byrne, ... Annals of neurology 78 (2), 222-234, 2015 | 62 | 2015 |