The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1046 | 2015 |
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ... Neuron 80 (2), 415-428, 2013 | 1031 | 2013 |
C9orf72 nucleotide repeat structures initiate molecular cascades of disease JDRJW Aaron R. Haeusler, Christopher J. Donnelly, Goran Nature, 2014 | 1018 | 2014 |
RNA binding antagonizes neurotoxic phase transitions of TDP-43 JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ... Neuron 102 (2), 321-338. e8, 2019 | 407 | 2019 |
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke S Li, JJ Overman, D Katsman, SV Kozlov, CJ Donnelly, JL Twiss, RJ Giger, ... Nature neuroscience 13 (12), 1496-1504, 2010 | 360 | 2010 |
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease AR Haeusler, CJ Donnelly, JD Rothstein Nature Reviews Neuroscience 17 (6), 383-395, 2016 | 235 | 2016 |
Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth CJ Donnelly, M Park, M Spillane, S Yoo, A Pacheco, C Gomes, ... Journal of Neuroscience 33 (8), 3311-3322, 2013 | 198 | 2013 |
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity CJ Donnelly, DE Willis, M Xu, C Tep, C Jiang, S Yoo, NC Schanen, ... The EMBO journal 30 (22), 4665-4677, 2011 | 174 | 2011 |
Concordant but varied phenotypes among Duchenne muscular dystrophy patient-specific myoblasts derived using a human iPSC-based model IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ... Cell reports 15 (10), 2301-2312, 2016 | 169 | 2016 |
Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex M Spillane, A Ketschek, CJ Donnelly, A Pacheco, JL Twiss, G Gallo Journal of Neuroscience 32 (49), 17671-17689, 2012 | 135 | 2012 |
Subcellular communication through RNA transport and localized protein synthesis CJ Donnelly, M Fainzilber, JL Twiss Traffic 11 (12), 1498-1505, 2010 | 135 | 2010 |
A HuD‐ZBP1 ribonucleoprotein complex localizes GAP‐43 mRNA into axons through its 3′ untranslated region AU‐rich regulatory element S Yoo, HH Kim, P Kim, CJ Donnelly, AL Kalinski, D Vuppalanchi, M Park, ... Journal of neurochemistry 126 (6), 792-804, 2013 | 94 | 2013 |
Axonal localization of transgene mRNA in mature PNS and CNS neurons DE Willis, M Xu, CJ Donnelly, C Tep, M Kendall, M Erenstheyn, ... Journal of Neuroscience 31 (41), 14481-14487, 2011 | 94 | 2011 |
WNK kinases sense molecular crowding and rescue cell volume via phase separation CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ... Cell 185 (24), 4488-4506. e20, 2022 | 76 | 2022 |
Nucleocytoplasmic proteomic analysis uncovers eRF1 and nonsense-mediated decay as modifiers of ALS/FTD C9orf72 toxicity JA Ortega, EL Daley, S Kour, M Samani, L Tellez, HS Smith, EA Hall, ... Neuron 106 (1), 90-107. e13, 2020 | 68 | 2020 |
RNA modulates physiological and neuropathological protein phase transitions JR Mann, CJ Donnelly Neuron 109 (17), 2663-2681, 2021 | 43 | 2021 |
Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment AM Haidet-Phillips, L Roybon, SK Gross, A Tuteja, CJ Donnelly, ... Stem cells translational medicine 3 (5), 575-585, 2014 | 42 | 2014 |
The Cloning and Characterization of the Histone Acetyltransferase Human Homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 Is Essential for … X Zhu, N Singh, C Donnelly, P Boimel, F Elefant Genetics 175 (3), 1229-1240, 2007 | 40 | 2007 |
Lysophosphatidic acid differentially regulates axonal mRNA translation through 5′ UTR elements D Vuppalanchi, TT Merianda, C Donnelly, A Pacheco, G Williams, S Yoo, ... Molecular and Cellular Neuroscience 50 (2), 136-146, 2012 | 37 | 2012 |
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology EN Anderson, AA Morera, S Kour, JD Cherry, N Ramesh, A Gleixner, ... Elife 10, e67587, 2021 | 36 | 2021 |