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Christopher Donnelly
Christopher Donnelly
Associate Professor of Neurobiology, Scientific Director, Live Like Lou Center for ALS Research
在 pitt.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ...
Nature 525 (7567), 56-61, 2015
10462015
RNA toxicity from the ALS/FTD C9ORF72 expansion is mitigated by antisense intervention
CJ Donnelly, PW Zhang, JT Pham, AR Haeusler, NA Mistry, S Vidensky, ...
Neuron 80 (2), 415-428, 2013
10312013
C9orf72 nucleotide repeat structures initiate molecular cascades of disease
JDRJW Aaron R. Haeusler, Christopher J. Donnelly, Goran
Nature, 2014
10182014
RNA binding antagonizes neurotoxic phase transitions of TDP-43
JR Mann, AM Gleixner, JC Mauna, E Gomes, MR DeChellis-Marks, ...
Neuron 102 (2), 321-338. e8, 2019
4072019
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke
S Li, JJ Overman, D Katsman, SV Kozlov, CJ Donnelly, JL Twiss, RJ Giger, ...
Nature neuroscience 13 (12), 1496-1504, 2010
3602010
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease
AR Haeusler, CJ Donnelly, JD Rothstein
Nature Reviews Neuroscience 17 (6), 383-395, 2016
2352016
Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth
CJ Donnelly, M Park, M Spillane, S Yoo, A Pacheco, C Gomes, ...
Journal of Neuroscience 33 (8), 3311-3322, 2013
1982013
Limited availability of ZBP1 restricts axonal mRNA localization and nerve regeneration capacity
CJ Donnelly, DE Willis, M Xu, C Tep, C Jiang, S Yoo, NC Schanen, ...
The EMBO journal 30 (22), 4665-4677, 2011
1742011
Concordant but varied phenotypes among Duchenne muscular dystrophy patient-specific myoblasts derived using a human iPSC-based model
IY Choi, HT Lim, K Estrellas, J Mula, TV Cohen, Y Zhang, CJ Donnelly, ...
Cell reports 15 (10), 2301-2312, 2016
1692016
Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex
M Spillane, A Ketschek, CJ Donnelly, A Pacheco, JL Twiss, G Gallo
Journal of Neuroscience 32 (49), 17671-17689, 2012
1352012
Subcellular communication through RNA transport and localized protein synthesis
CJ Donnelly, M Fainzilber, JL Twiss
Traffic 11 (12), 1498-1505, 2010
1352010
A HuD‐ZBP1 ribonucleoprotein complex localizes GAP‐43 mRNA into axons through its 3′ untranslated region AU‐rich regulatory element
S Yoo, HH Kim, P Kim, CJ Donnelly, AL Kalinski, D Vuppalanchi, M Park, ...
Journal of neurochemistry 126 (6), 792-804, 2013
942013
Axonal localization of transgene mRNA in mature PNS and CNS neurons
DE Willis, M Xu, CJ Donnelly, C Tep, M Kendall, M Erenstheyn, ...
Journal of Neuroscience 31 (41), 14481-14487, 2011
942011
WNK kinases sense molecular crowding and rescue cell volume via phase separation
CR Boyd-Shiwarski, DJ Shiwarski, SE Griffiths, RT Beacham, L Norrell, ...
Cell 185 (24), 4488-4506. e20, 2022
762022
Nucleocytoplasmic proteomic analysis uncovers eRF1 and nonsense-mediated decay as modifiers of ALS/FTD C9orf72 toxicity
JA Ortega, EL Daley, S Kour, M Samani, L Tellez, HS Smith, EA Hall, ...
Neuron 106 (1), 90-107. e13, 2020
682020
RNA modulates physiological and neuropathological protein phase transitions
JR Mann, CJ Donnelly
Neuron 109 (17), 2663-2681, 2021
432021
Gene profiling of human induced pluripotent stem cell-derived astrocyte progenitors following spinal cord engraftment
AM Haidet-Phillips, L Roybon, SK Gross, A Tuteja, CJ Donnelly, ...
Stem cells translational medicine 3 (5), 575-585, 2014
422014
The Cloning and Characterization of the Histone Acetyltransferase Human Homolog Dmel\TIP60 in Drosophila melanogaster: Dmel\TIP60 Is Essential for …
X Zhu, N Singh, C Donnelly, P Boimel, F Elefant
Genetics 175 (3), 1229-1240, 2007
402007
Lysophosphatidic acid differentially regulates axonal mRNA translation through 5′ UTR elements
D Vuppalanchi, TT Merianda, C Donnelly, A Pacheco, G Williams, S Yoo, ...
Molecular and Cellular Neuroscience 50 (2), 136-146, 2012
372012
Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology
EN Anderson, AA Morera, S Kour, JD Cherry, N Ramesh, A Gleixner, ...
Elife 10, e67587, 2021
362021
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