Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology JG Kiang, GC Tsokos Pharmacology & therapeutics 80 (2), 183-201, 1998 | 1631 | 1998 |
New insights into the immunopathogenesis of systemic lupus erythematosus GC Tsokos, MS Lo, PC Reis, KE Sullivan Nature Reviews Rheumatology 12 (12), 716-730, 2016 | 1128 | 2016 |
Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys JC Crispín, M Oukka, G Bayliss, RA Cohen, CA Van Beek, IE Stillman, ... The journal of immunology 181 (12), 8761-8766, 2008 | 916 | 2008 |
Interleukin-17 and systemic lupus erythematosus: current concepts A Nalbandian, JC Crispin, GC Tsokos Clinical & Experimental Immunology 157 (2), 209-215, 2009 | 516 | 2009 |
Pathogenesis of human systemic lupus erythematosus: recent advances JC Crispín, SNC Liossis, K Kis-Toth, LA Lieberman, VC Kyttaris, YT Juang, ... Trends in molecular medicine 16 (2), 47-57, 2010 | 501 | 2010 |
T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with … S Shivakumar, GC Tsokos, SK Datta Journal of immunology (Baltimore, Md.: 1950) 143 (1), 103-112, 1989 | 467 | 1989 |
Pathogenesis of human systemic lupus erythematosus: a cellular perspective VR Moulton, A Suarez-Fueyo, E Meidan, H Li, M Mizui, GC Tsokos Trends in molecular medicine 23 (7), 615-635, 2017 | 422 | 2017 |
Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta … SN Liossis, XZ Ding, GJ Dennis, GC Tsokos The Journal of clinical investigation 101 (7), 1448-1457, 1998 | 408 | 1998 |
Autoimmunity and organ damage in systemic lupus erythematosus GC Tsokos Nature immunology 21 (6), 605-614, 2020 | 388 | 2020 |
The role of IL-23/IL-17 axis in lupus nephritis Z Zhang, VC Kyttaris, GC Tsokos The Journal of Immunology 183 (5), 3160-3169, 2009 | 359 | 2009 |
Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2 … RF van Vollenhoven, BH Hahn, GC Tsokos, CL Wagner, P Lipsky, ... The Lancet 392 (10155), 1330-1339, 2018 | 327 | 2018 |
systemic lupus erythematosus RG Lahita, G Tsokos, J Buyon, K Takao | 312 | 2010 |
B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. SN Liossis, B Kovacs, G Dennis, GM Kammer, GC Tsokos The Journal of clinical investigation 98 (11), 2549-2557, 1996 | 302 | 1996 |
T cells as therapeutic targets in SLE JC Crispín, VC Kyttaris, C Terhorst, GC Tsokos Nature Reviews Rheumatology 6 (6), 317-325, 2010 | 295 | 2010 |
Regulatory T cells in the treatment of disease A Sharabi, MG Tsokos, Y Ding, TR Malek, D Klatzmann, GC Tsokos Nature reviews Drug discovery 17 (11), 823-844, 2018 | 285 | 2018 |
Systemic lupus erythematosus serum IgG increases CREM binding to the IL-2 promoter and suppresses IL-2 production through CaMKIV YT Juang, Y Wang, EE Solomou, Y Li, C Mawrin, K Tenbrock, VC Kyttaris, ... The Journal of clinical investigation 115 (4), 996-1005, 2005 | 269 | 2005 |
Immunopathogenesis and spectrum of infections in systemiclupus erythematosus AG Iliopoulos, GC Tsokos Seminars in arthritis and rheumatism 25 (5), 318-336, 1996 | 263 | 1996 |
Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8-T helper cell lines that express the gamma delta T … S Rajagopalan, T Zordan, GC Tsokos, SK Datta Proceedings of the National Academy of Sciences 87 (18), 7020-7024, 1990 | 253 | 1990 |
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification ME Munroe, R Lu, YD Zhao, DA Fife, JM Robertson, JM Guthridge, ... Annals of the rheumatic diseases 75 (11), 2014-2021, 2016 | 245 | 2016 |
Mechanisms of immune complex–mediated neutrophil recruitment and tissue injury TN Mayadas, GC Tsokos, N Tsuboi Circulation 120 (20), 2012-2024, 2009 | 245 | 2009 |