An environmental bacterial taxon with a large and distinct metabolic repertoire MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ... Nature 506 (7486), 58-62, 2014 | 622 | 2014 |
Complete biosynthetic pathway of anditomin: nature’s sophisticated synthetic route to a complex fungal meroterpenoid Y Matsuda, T Wakimoto, T Mori, T Awakawa, I Abe Journal of the American Chemical Society 136 (43), 15326-15336, 2014 | 167 | 2014 |
Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1 A Kita, S Matsunaga, A Takai, H Kataiwa, T Wakimoto, N Fusetani, ... Structure 10 (5), 715-724, 2002 | 153 | 2002 |
Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont T Wakimoto, Y Egami, Y Nakashima, Y Wakimoto, T Mori, T Awakawa, ... Nature chemical biology 10 (8), 648-655, 2014 | 141 | 2014 |
Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides L Zhang, T Hashimoto, B Qin, J Hashimoto, I Kozone, T Kawahara, ... Angewandte Chemie International Edition 56 (7), 1740-1745, 2017 | 138 | 2017 |
Furan fatty acid as an anti-inflammatory component from the green-lipped mussel Perna canaliculus T Wakimoto, H Kondo, H Nii, K Kimura, Y Egami, Y Oka, M Yoshida, ... Proceedings of the National Academy of Sciences 108 (42), 17533-17537, 2011 | 136 | 2011 |
Total synthesis of (−)-serotobenine Y Koizumi, H Kobayashi, T Wakimoto, T Furuta, T Fukuyama, T Kan Journal of the American Chemical Society 130 (50), 16854-16855, 2008 | 127 | 2008 |
Spiro-ring formation is catalyzed by a multifunctional dioxygenase in austinol biosynthesis Y Matsuda, T Awakawa, T Wakimoto, I Abe Journal of the American Chemical Society 135 (30), 10962-10965, 2013 | 125 | 2013 |
An Unusual Chimeric Diterpene Synthase from Emericella variecolor and Its Functional Conversion into a Sesterterpene Synthase by Domain Swapping B Qin, Y Matsuda, T Mori, M Okada, Z Quan, T Mitsuhashi, T Wakimoto, ... Angewandte Chemie International Edition 55 (5), 1658-1661, 2016 | 112 | 2016 |
Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase Y Matsuda, T Iwabuchi, T Wakimoto, T Awakawa, I Abe Journal of the American Chemical Society 137 (9), 3393-3401, 2015 | 110 | 2015 |
Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase H Morita, M Yamashita, SP Shi, T Wakimoto, S Kondo, R Kato, S Sugio, ... Proceedings of the National Academy of Sciences 108 (33), 13504-13509, 2011 | 92 | 2011 |
Terretonin biosynthesis requires methylation as essential step for cyclization Y Matsuda, T Awakawa, T Itoh, T Wakimoto, T Kushiro, I Fujii, Y Ebizuka, ... ChemBioChem 13 (12), 1738-1741, 2012 | 88 | 2012 |
A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis T Awakawa, L Zhang, T Wakimoto, S Hoshino, T Mori, T Ito, J Ishikawa, ... Journal of the American Chemical Society 136 (28), 9910-9913, 2014 | 82 | 2014 |
Niizalactams A–C, Multicyclic Macrolactams Isolated from Combined Culture of Streptomyces with Mycolic Acid-Containing Bacterium S Hoshino, M Okada, T Wakimoto, H Zhang, F Hayashi, H Onaka, I Abe Journal of natural products 78 (12), 3011-3017, 2015 | 78 | 2015 |
Chojalactones A–C, Cytotoxic Butanolides Isolated from Streptomyces sp. Cultivated with Mycolic Acid Containing Bacterium S Hoshino, T Wakimoto, H Onaka, I Abe Organic letters 17 (6), 1501-1504, 2015 | 77 | 2015 |
Calyxamides A and B, Cytotoxic Cyclic Peptides from the Marine Sponge Discodermia calyx M Kimura, T Wakimoto, Y Egami, KC Tan, Y Ise, I Abe Journal of Natural Products 75 (2), 290-294, 2012 | 74 | 2012 |
Concise total synthesis of flavone C-glycoside having potent anti-inflammatory activity T Furuta, T Kimura, S Kondo, H Mihara, T Wakimoto, H Nukaya, K Tsuji, ... Tetrahedron 60 (42), 9375-9379, 2004 | 73 | 2004 |
Discovery of unprecedented hydrazine-forming machinery in bacteria K Matsuda, T Tomita, K Shin-Ya, T Wakimoto, T Kuzuyama, M Nishiyama Journal of the American Chemical Society 140 (29), 9083-9086, 2018 | 71 | 2018 |
Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining T Awakawa, XL Yang, T Wakimoto, I Abe Chembiochem: a European journal of chemical biology 14 (16), 2095-2099, 2013 | 68 | 2013 |
Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823 S Hoshino, L Zhang, T Awakawa, T Wakimoto, H Onaka, I Abe The Journal of Antibiotics 68 (5), 342-344, 2015 | 65 | 2015 |