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Two levels of protection for the B cell genome during somatic hypermutation M Liu, JL Duke, DJ Richter, CG Vinuesa, CC Goodnow, SH Kleinstein, ... Nature 451 (7180), 841-845, 2008 | 689 | 2008 |
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ... Bioinformatics 31 (20), 3356-3358, 2015 | 660 | 2015 |
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone SM Kerfoot, G Yaari, JR Patel, KL Johnson, DG Gonzalez, SH Kleinstein, ... Immunity 34 (6), 947-960, 2011 | 576 | 2011 |
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ... Science translational medicine 6 (248), 248ra107-248ra107, 2014 | 459 | 2014 |
CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype GV Zuccarino-Catania, S Sadanand, FJ Weisel, MM Tomayko, H Meng, ... Nature immunology 15 (7), 631-637, 2014 | 434 | 2014 |
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ... Bioinformatics 30 (13), 1930-1932, 2014 | 432 | 2014 |
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns AE Hauser, T Junt, TR Mempel, MW Sneddon, SH Kleinstein, ... Immunity 26 (5), 655-667, 2007 | 366 | 2007 |
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4+ cell properties during viral infection HD Marshall, A Chandele, YW Jung, H Meng, AC Poholek, IA Parish, ... Immunity 35 (4), 633-646, 2011 | 339 | 2011 |
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders S Brioschi, WL Wang, V Peng, M Wang, I Shchukina, ZJ Greenberg, ... Science 373 (6553), eabf9277, 2021 | 262 | 2021 |
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection CX Dominguez, RA Amezquita, T Guan, HD Marshall, NS Joshi, ... Journal of Experimental Medicine 212 (12), 2041-2056, 2015 | 255 | 2015 |
Practical guidelines for B-cell receptor repertoire sequencing analysis G Yaari, SH Kleinstein Genome medicine 7, 1-14, 2015 | 247 | 2015 |
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ... Frontiers in immunology 4, 358, 2013 | 246 | 2013 |
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity K Bryniarski, W Ptak, A Jayakumar, K Püllmann, MJ Caplan, ... Journal of Allergy and Clinical Immunology 132 (1), 170-181. e9, 2013 | 245 | 2013 |
Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells VM Bruno, S Hannemann, M Lara-Tejero, RA Flavell, SH Kleinstein, ... PLoS pathogens 5 (8), e1000538, 2009 | 243 | 2009 |
Dynamic expression profiling of type I and type III interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression CR Bolen, S Ding, MD Robek, SH Kleinstein Hepatology 59 (4), 1262-1272, 2014 | 226 | 2014 |
Human germinal centres engage memory and naive B cells after influenza vaccination JS Turner, JQ Zhou, J Han, AJ Schmitz, AA Rizk, WB Alsoussi, T Lei, ... Nature 586 (7827), 127-132, 2020 | 221 | 2020 |
Automated analysis of high-throughput B-cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles D Gadala-Maria, G Yaari, M Uduman, SH Kleinstein Proceedings of the National Academy of Sciences 112 (8), E862-E870, 2015 | 220 | 2015 |
Polycomb repressive complex 2-mediated chromatin repression guides effector CD8+ T cell terminal differentiation and loss of multipotency SM Gray, RA Amezquita, T Guan, SH Kleinstein, SM Kaech Immunity 46 (4), 596-608, 2017 | 218 | 2017 |
Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ... Immunity 43 (1), 120-131, 2015 | 217 | 2015 |