A chromatin integration labelling method enables epigenomic profiling with lower input A Harada, K Maehara, T Handa, Y Arimura, J Nogami, ... Nature cell biology 21 (2), 287-296, 2019 | 158 | 2019 |
Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing S Tashiro, T Handa, A Matsuda, T Ban, T Takigawa, K Miyasato, K Ishii, ... Nature communications 7 (1), 10393, 2016 | 53 | 2016 |
DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast T Handa, M Kanke, TS Takahashi, T Nakagawa, H Masukata Molecular biology of the cell 23 (16), 3240-3253, 2012 | 46 | 2012 |
Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene LS Forero-Quintero, W Raymond, T Handa, MN Saxton, T Morisaki, ... Nature Communications 12 (1), 3158, 2021 | 43 | 2021 |
H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing SJD Tjalsma, M Hori, Y Sato, A Bousard, A Ohi, AC Raposo, J Roensch, ... EMBO reports 22 (3), e51989, 2021 | 40 | 2021 |
Targeted DNA methylation in pericentromeres with genome editing-based artificial DNA methyltransferase T Yamazaki, Y Hatano, T Handa, S Kato, K Hoida, R Yamamura, ... PLoS One 12 (5), e0177764, 2017 | 38 | 2017 |
Signs of biological activities of 28,000-year-old mammoth nuclei in mouse oocytes visualized by live-cell imaging K Yamagata, K Nagai, H Miyamoto, M Anzai, H Kato, K Miyamoto, ... Scientific Reports 9 (1), 4050, 2019 | 36 | 2019 |
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq) DA Bartlett, V Dileep, T Handa, Y Ohkawa, H Kimura, S Henikoff, ... Journal of Cell Biology 220 (12), e202103078, 2021 | 28 | 2021 |
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe S Uchino, Y Ito, Y Sato, T Handa, Y Ohkawa, M Tokunaga, H Kimura Journal of Cell Biology 221 (2), e202104134, 2021 | 25* | 2021 |
Shelterin promotes tethering of late replication origins to telomeres for replication‐timing control S Ogawa, S Kido, T Handa, H Ogawa, H Asakawa, TS Takahashi, ... The EMBO Journal 37 (15), e98997, 2018 | 16 | 2018 |
Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input T Handa, A Harada, K Maehara, S Sato, M Nakao, N Goto, H Kurumizaka, ... Nature Protocols 15 (10), 3334-3360, 2020 | 15 | 2020 |
Beyond SAHF: An integrative view of chromatin compartmentalization during senescence I Olan, T Handa, M Narita Current Opinion in Cell Biology 83, 102206, 2023 | 6 | 2023 |
Transient methionine deprivation triggers histone modification and potentiates differentiation of induced pluripotent stem cells H Ozawa, A Kambe, K Hibi, S Murakami, A Oikawa, T Handa, K Fujiki, ... Stem Cells 41 (3), 271-286, 2023 | 4 | 2023 |
Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections K Maehara, K Tomimatsu, A Harada, K Tanaka, S Sato, M Fukuoka, ... Molecular Systems Biology 17 (11), e10323, 2021 | 2 | 2021 |
Detailed protocol─ Chromatin Integration labeling T Handa, A Harada, K Maehara, Y Ohkawa, H Kimura Protocol Exchange, 2018 | 2 | 2018 |
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin N Goto, K Suke, N Yonezawa, H Nishihara, T Handa, Y Sato, T Kujirai, ... Journal of Cell Biology 223 (8), e202310084, 2024 | 1 | 2024 |
Author Correction: Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input T Handa, A Harada, K Maehara, S Sato, M Nakao, N Goto, H Kurumizaka, ... Nature Protocols 19 (4), 1288-1288, 2024 | | 2024 |
HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity M Narita, I Olan, M Ando-Kuri, A Parry, T Handa, S Schoenfelder, P Fraser, ... | | 2024 |
Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input (vol 15, pg 3334, 2020) T Handa, A Harada, K Maehara, S Sato, M Nakao, N Goto, H Kurumizaka, ... NATURE PROTOCOLS 19 (1), 2024 | | 2024 |
Method for inserting desired DNA fragment into site located adjacent to binding domain of DNA-binding protein Y Ohkawa, A Harada, H Kurumizaka, H Kimura, T Handa, Y Sato, ... US Patent 11,414,680, 2022 | | 2022 |