Functionally significant insulin-like growth factor I receptor mutations in centenarians Y Suh, G Atzmon, MO Cho, D Hwang, B Liu, DJ Leahy, N Barzilai, ... Proceedings of the National Academy of Sciences 105 (9), 3438-3442, 2008 | 879 | 2008 |
Interventions to slow aging in humans: are we ready? VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ... Aging cell 14 (4), 497-510, 2015 | 630 | 2015 |
Genome instability and aging J Vijg, Y Suh Annual review of physiology 75 (1), 645-668, 2013 | 429 | 2013 |
Differences between germline and somatic mutation rates in humans and mice B Milholland, X Dong, L Zhang, X Hao, Y Suh, J Vijg Nature communications 8 (1), 15183, 2017 | 416 | 2017 |
Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians G Atzmon, M Cho, RM Cawthon, T Budagov, M Katz, X Yang, G Siegel, ... Proceedings of the National Academy of Sciences 107 (suppl_1), 1710-1717, 2010 | 320 | 2010 |
Deficient chaperone-mediated autophagy in liver leads to metabolic dysregulation JL Schneider, Y Suh, AM Cuervo Cell metabolism 20 (3), 417-432, 2014 | 304 | 2014 |
SNP discovery in associating genetic variation with human disease phenotypes Y Suh, J Vijg Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 573 (1 …, 2005 | 270 | 2005 |
Delayed and accelerated aging share common longevity assurance mechanisms B Schumacher, I Van Der Pluijm, MJ Moorhouse, T Kosteas, AR Robinson, ... PLoS genetics 4 (8), e1000161, 2008 | 255 | 2008 |
A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging MA McCormick, JR Delaney, M Tsuchiya, S Tsuchiyama, A Shemorry, ... Cell metabolism 22 (5), 895-906, 2015 | 254 | 2015 |
Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: implication to age-associated bone diseases and … MJ Kim, CW Kim, YS Choi, MH Kim, CJ Park, Y Suh Mechanisms of ageing and development 133 (5), 215-225, 2012 | 252 | 2012 |
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria B Liu, S Ghosh, X Yang, H Zheng, X Liu, Z Wang, G Jin, B Zheng, ... Cell metabolism 16 (6), 738-750, 2012 | 229 | 2012 |
Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage C Park, Y Suh, AM Cuervo Nature communications 6 (1), 6823, 2015 | 209 | 2015 |
Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis J Lee, PK Saha, QH Yang, S Lee, JY Park, Y Suh, SK Lee, L Chan, ... Proceedings of the National Academy of Sciences 105 (49), 19229-19234, 2008 | 205 | 2008 |
Genetics of longevity and aging J Vijg, Y Suh Annu. Rev. Med. 56 (1), 193-212, 2005 | 200 | 2005 |
Regulation of IGF-1 signaling by microRNAs HJ Jung, Y Suh Frontiers in genetics 5, 472, 2015 | 162 | 2015 |
MRP2 haplotypes confer differential susceptibility to toxic liver injury JH Choi, BM Ahn, J Yi, JH Lee, JH Lee, SW Nam, CY Chon, KH Han, ... Pharmacogenetics and genomics 17 (6), 403-415, 2007 | 162 | 2007 |
In vivo genome editing in animals using AAV-CRISPR system: applications to translational research of human disease CH Lau, Y Suh F1000Research 6, 2017 | 156 | 2017 |
LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control J Wang, F Telese, Y Tan, W Li, C Jin, X He, H Basnet, Q Ma, D Merkurjev, ... Nature neuroscience 18 (9), 1256-1264, 2015 | 156 | 2015 |
A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases JH Lee, JH Choi, W Namkung, JW Hanrahan, J Chang, SY Song, ... Human molecular genetics 12 (18), 2321-2332, 2003 | 144 | 2003 |
Age-related somatic mutations in the cancer genome B Milholland, A Auton, Y Suh, J Vijg Oncotarget 6 (28), 24627, 2015 | 141 | 2015 |