| Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study RA Evans, H McAuley, EM Harrison, A Shikotra, A Singapuri, M Sereno, ... The Lancet Respiratory Medicine 9 (11), 1275-1287, 2021 | 510 | 2021 |
| Multicentre evaluation of multidisciplinary team meeting agreement on diagnosis in diffuse parenchymal lung disease: a case-cohort study SLF Walsh, AU Wells, SR Desai, V Poletti, S Piciucchi, A Dubini, H Nunes, ... The lancet Respiratory medicine 4 (7), 557-565, 2016 | 444 | 2016 |
| Familial dementia caused by polymerization of mutant neuroserpin RL Davis, AE Shrimpton, PD Holohan, C Bradshaw, D Feiglin, GH Collins, ... Nature 401 (6751), 376-379, 1999 | 438 | 1999 |
| Conformational changes and disease—serpins, prions and Alzheimer's RW Carrell, B Gooptu Current Opinion in Structural Biology 8 (6), 799-809, 1998 | 345 | 1998 |
| Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ... The Lancet Respiratory Medicine 10 (8), 761-775, 2022 | 317 | 2022 |
| Conformational pathology of the serpins: themes, variations, and therapeutic strategies B Gooptu, DA Lomas Annual review of biochemistry 78 (1), 147-176, 2009 | 309 | 2009 |
| Inactive conformation of the serpin α1-antichymotrypsin indicates two-stage insertion of the reactive loop: Implications for inhibitory function and conformational … B Gooptu, B Hazes, WSW Chang, TR Dafforn, RW Carrell, RJ Read, ... Proceedings of the National Academy of Sciences 97 (1), 67-72, 2000 | 218 | 2000 |
| Mechanisms of emphysema in α1-antitrypsin deficiency: molecular and cellular insights B Gooptu, UI Ekeowa, DA Lomas European Respiratory Journal 34 (2), 475-488, 2009 | 199 | 2009 |
| A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1‐antitrypsin deficiency E Miranda, J Pérez, UI Ekeowa, N Hadzic, N Kalsheker, B Gooptu, ... Hepatology 52 (3), 1078-1088, 2010 | 171 | 2010 |
| Defining the mechanism of polymerization in the serpinopathies UI Ekeowa, J Freeke, E Miranda, B Gooptu, MF Bush, J Pérez, J Teckman, ... Proceedings of the National Academy of Sciences 107 (40), 17146-17151, 2010 | 157 | 2010 |
| Small Molecules Block the Polymerization of Z α1-Antitrypsin and Increase the Clearance of Intracellular Aggregates M Mallya, RL Phillips, SA Saldanha, B Gooptu, SC Leigh Brown, ... Journal of medicinal chemistry 50 (22), 5357-5363, 2007 | 140 | 2007 |
| The molecular and cellular pathology of α1-antitrypsin deficiency B Gooptu, JA Dickens, DA Lomas Trends in molecular medicine 20 (2), 116-127, 2014 | 123 | 2014 |
| Polymers and inflammation: disease mechanisms of the serpinopathies B Gooptu, DA Lomas The Journal of experimental medicine 205 (7), 1529-1534, 2008 | 95 | 2008 |
| Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled … JJ Solomon, SK Danoff, FA Woodhead, S Hurwitz, R Maurer, I Glaspole, ... The Lancet Respiratory Medicine 11 (1), 87-96, 2023 | 94 | 2023 |
| SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination F Liew, S Talwar, A Cross, BJ Willett, S Scott, N Logan, MK Siggins, ... EBioMedicine 87, 2023 | 75 | 2023 |
| Update on alpha-1 antitrypsin deficiency: new therapies DA Lomas, JR Hurst, B Gooptu Journal of Hepatology 65 (2), 413-424, 2016 | 74 | 2016 |
| Residual lung abnormalities after COVID-19 hospitalization: interim analysis of the UKILD post–COVID-19 study I Stewart, J Jacob, PM George, PL Molyneaux, JC Porter, RJ Allen, ... American journal of respiratory and critical care medicine 207 (6), 693-703, 2023 | 73 | 2023 |
| α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies UI Ekeowa, B Gooptu, D Belorgey, P Hägglöf, S Karlsson-Li, E Miranda, ... Clinical science 116 (12), 837-850, 2009 | 72 | 2009 |
| hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiency CP Segeritz, ST Rashid, MC de Brito, MP Serra, A Ordonez, CM Morell, ... Journal of hepatology 69 (4), 851-860, 2018 | 52 | 2018 |
| Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization AM Fra, B Gooptu, I Ferrarotti, E Miranda, R Scabini, R Ronzoni, F Benini, ... PLoS One 7 (6), e38405, 2012 | 52 | 2012 |
