TEER measurement techniques for in vitro barrier model systems B Srinivasan, AR Kolli, MB Esch, HE Abaci, ML Shuler, JJ Hickman Journal of laboratory automation 20 (2), 107-126, 2015 | 1998 | 2015 |
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs C Oleaga, C Bernabini, AST Smith, B Srinivasan, M Jackson, W McLamb, ... Scientific reports 6 (1), 20030, 2016 | 405 | 2016 |
The role of body-on-a-chip devices in drug and toxicity studies MB Esch, TL King, ML Shuler Annual review of biomedical engineering 13 (1), 55-72, 2011 | 398 | 2011 |
Oral exposure to polystyrene nanoparticles affects iron absorption GJ Mahler, MB Esch, E Tako, TL Southard, SD Archer, RP Glahn, ... Nature nanotechnology 7 (4), 264-271, 2012 | 364 | 2012 |
Microfabricated mammalian organ systems and their integration into models of whole animals and humans JH Sung, MB Esch, JM Prot, CJ Long, A Smith, JJ Hickman, ML Shuler Lab on a Chip 13 (7), 1201-1212, 2013 | 280 | 2013 |
Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity GJ Mahler, MB Esch, RP Glahn, ML Shuler Biotechnology and bioengineering 104 (1), 193-205, 2009 | 272 | 2009 |
Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury MB Esch, GJ Mahler, T Stokol, ML Shuler Lab on a Chip 14 (16), 3081-3092, 2014 | 271 | 2014 |
Modular, pumpless body-on-a-chip platform for the co-culture of GI tract epithelium and 3D primary liver tissue MB Esch, H Ueno, DR Applegate, ML Shuler Lab on a Chip 16 (14), 2719-2729, 2016 | 212 | 2016 |
On chip porous polymer membranes for integration of gastrointestinal tract epithelium with microfluidic ‘body-on-a-chip’devices MB Esch, JH Sung, J Yang, C Yu, J Yu, JC March, ML Shuler Biomedical microdevices 14, 895-906, 2012 | 208 | 2012 |
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow MB Esch, JM Prot, YI Wang, P Miller, JR Llamas-Vidales, BA Naughton, ... Lab on a Chip 15 (10), 2269-2277, 2015 | 181 | 2015 |
How multi-organ microdevices can help foster drug development MB Esch, AST Smith, JM Prot, C Oleaga, JJ Hickman, ML Shuler Advanced drug delivery reviews 69, 158-169, 2014 | 169 | 2014 |
Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure JH Sung, B Srinivasan, MB Esch, WT McLamb, C Bernabini, ML Shuler, ... Experimental biology and medicine 239 (9), 1225-1239, 2014 | 146 | 2014 |
Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function MD Guillemette, B Cui, E Roy, R Gauvin, CJ Giasson, MB Esch, P Carrier, ... Integrative Biology 1 (2), 196-204, 2009 | 137 | 2009 |
Modeling barrier tissues in vitro: methods, achievements, and challenges CM Sakolish, MB Esch, JJ Hickman, ML Shuler, GJ Mahler EBioMedicine 5, 30-39, 2016 | 132 | 2016 |
Influence of master fabrication techniques on the characteristics of embossed microfluidic channels MB Esch, S Kapur, G Irizarry, V Genova Lab on a Chip 3 (2), 121-127, 2003 | 117 | 2003 |
Detection of Viable Cryptosporidium parvum Using DNA-Modified Liposomes in a Microfluidic Chip MB Esch, LE Locascio, MJ Tarlov, RA Durst Analytical Chemistry 73 (13), 2952-2958, 2001 | 111 | 2001 |
Integration of in silico and in vitro platforms for pharmacokinetic–pharmacodynamic modeling JH Sung, MB Esch, ML Shuler Expert opinion on drug metabolism & toxicology 6 (9), 1063-1081, 2010 | 89 | 2010 |
Detection of Cryptosporidium parvum Using Oligonucleotide-Tagged Liposomes in a Competitive Assay Format MB Esch, AJ Baeumner, RA Durst Analytical Chemistry 73 (13), 3162-3167, 2001 | 86 | 2001 |
Characterization of In Vitro Endothelial Linings Grown Within Microfluidic Channels MB Esch, DJ Post, ML Shuler, T Stokol Tissue Engineering Part A 17 (23-24), 2965-2971, 2011 | 81 | 2011 |
Self-contained, low-cost Body-on-a-Chip systems for drug development YI Wang, C Oleaga, CJ Long, MB Esch, CW McAleer, PG Miller, ... Experimental biology and medicine 242 (17), 1701-1713, 2017 | 66 | 2017 |