Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands SJ Broughton, MDW Piper, T Ikeya, TM Bass, J Jacobson, Y Driege, ... Proceedings of the National Academy of Sciences 102 (8), 3105-3110, 2005 | 954 | 2005 |
Molecular Evolution and Functional Characterization of Drosophila Insulin-Like Peptides S Grönke, DF Clarke, S Broughton, TD Andrews, L Partridge PLoS genetics 6 (2), e1000857, 2010 | 702 | 2010 |
Insulin/IGF-like signalling, the central nervous system and aging S Broughton, L Partridge Biochemical Journal 418 (1), 1-12, 2009 | 284 | 2009 |
Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs S Broughton, N Alic, C Slack, T Bass, T Ikeya, G Vinti, AM Tommasi, ... PloS one 3 (11), e3721, 2008 | 228 | 2008 |
The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila T Ikeya, S Broughton, N Alic, R Grandison, L Partridge Proceedings of the Royal Society B: Biological Sciences 276 (1674), 3799-3807, 2009 | 165 | 2009 |
DILP‐producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition SJ Broughton, C Slack, N Alic, A Metaxakis, TM Bass, Y Driege, ... Aging cell 9 (3), 336-346, 2010 | 143 | 2010 |
Excitatory and inhibitory switches for courtship in the brain of Drosophila melanogaster SJ Broughton, T Kitamoto, RJ Greenspan Current Biology 14 (7), 538-547, 2004 | 84 | 2004 |
Cell-nonautonomous effects of dFOXO/DAF-16 in aging N Alic, JM Tullet, T Niccoli, S Broughton, MP Hoddinott, C Slack, D Gems, ... Cell reports 6 (4), 608-616, 2014 | 64 | 2014 |
The Drosophila insulin receptor independently modulates lifespan and locomotor senescence MZBH Ismail, MD Hodges, M Boylan, R Achall, A Shirras, SJ Broughton PLoS One 10 (5), e0125312, 2015 | 41 | 2015 |
Endogenously inhibited protein kinase C in transgenic Drosophila embryonic neuroblasts down regulates the outgrowth of type I and II processes of cultured mature neurons SJ Broughton, NS Kane, B Arthur, M Yoder, RJ Greenspan, A Robichon Journal of cellular biochemistry 60 (4), 584-599, 1996 | 29 | 1996 |
Partial inhibition of RNA polymerase I promotes animal health and longevity GM Corrales, D Filer, KC Wenz, A Rogan, G Phillips, M Li, Y Feseha, ... Cell reports 30 (6), 1661-1669. e4, 2020 | 28 | 2020 |
Behavioral senescence and aging-related changes in motor neurons and brain neuromodulator levels are ameliorated by lifespan-extending reproductive dormancy in Drosophila S Liao, S Broughton, DR Nässel Frontiers in cellular neuroscience 11, 111, 2017 | 25 | 2017 |
Conditioning deficits of CaM-kinase transgenic Drosophila melanogaster in a new excitatory courtship assay SJ Broughton, T Tully, RJ Greenspan Journal of neurogenetics 17 (1), 91-102, 2003 | 20 | 2003 |
Ketamine restores thalamic-prefrontal cortex functional connectivity in a mouse model of neurodevelopmental disorder-associated 2p16. 3 deletion R B Hughes, J Whittingham-Dowd, RE Simmons, SJ Clapcote, ... Cerebral Cortex 30 (4), 2358-2371, 2020 | 16 | 2020 |
Loss of angiotensin-converting enzyme-related (ACER) peptidase disrupts behavioural and metabolic responses to diet in Drosophila melanogaster Z Glover, MD Hodges, N Dravecz, J Cameron, H Askwith, A Shirras, ... Journal of Experimental Biology 222 (8), jeb194332, 2019 | 12 | 2019 |
Microbes, molecular mimicry and molecules of mood and motivation JA Morris, SJ Broughton, Q Wessels Medical Hypotheses 87, 40-43, 2016 | 11 | 2016 |
Transport of CaM kinase along processes elicited by neuronal contact evokes an inhibition of arborization and outgrowth in D. melanogaster cultured neurons SJ Broughton, NS Kane, M Yoder, RJ Greenspan, A Robichon Journal of cellular biochemistry 62 (4), 484-494, 1996 | 10 | 1996 |
Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16. 3 deletion RB Hughes, J Whittingham‐Dowd, SJ Clapcote, SJ Broughton, N Dawson Autism Research 15 (4), 614-627, 2022 | 9 | 2022 |
Differential regulation of E-cadherin expression by the soluble ectodomain and intracellular domain of Jagged1 C Delury, C Tinker, S Rivers, M Hodges, S Broughton, E Parkin International Journal of Biochemistry Research & Review 3 (4), 278-290, 2013 | 4 | 2013 |
Response to thermal and infection stresses in an American vector of visceral leishmaniasis KA Martins, CS Morais, SJ Broughton, CR Lazzari, PA Bates, MH Pereira, ... Medical and Veterinary Entomology 37 (2), 238-251, 2023 | 2 | 2023 |