Oxygen isotope systematics of biologically mediated reactions of phosphate: I. Microbial degradation of organophosphorus compounds RE Blake, JR O'neil, GA Garcia Geochimica et Cosmochimica Acta 61 (20), 4411-4422, 1997 | 294 | 1997 |
Rifamycins–obstacles and opportunities PA Aristoff, GA Garcia, PD Kirchhoff, HDH Showalter Tuberculosis 90 (2), 94-118, 2010 | 224 | 2010 |
Confirmation of a second natural preQ1 aptamer class in Streptococcaceae bacteria MM Meyer, A Roth, SM Chervin, GA Garcia, RR Breaker Rna 14 (4), 685-695, 2008 | 146 | 2008 |
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis R Brenk, L Naerum, U Grädler, HD Gerber, GA Garcia, K Reuter, ... Journal of medicinal chemistry 46 (7), 1133-1143, 2003 | 129 | 2003 |
Effects of microbial activity on the δ18O of dissolved inorganic phosphate and textural features of synthetic apatites RE Blake, JR O’Neil, GA Garcia American Mineralogist 83 (11), 1516-1531, 1998 | 121 | 1998 |
A new target for shigellosis: rational design and crystallographic studies of inhibitors of tRNA-guanine transglycosylase U Grädler, HD Gerber, DAM Goodenough-Lashua, GA Garcia, R Ficner, ... Journal of molecular biology 306 (3), 455-467, 2001 | 106 | 2001 |
Enzyme-mediated precipitation of parent drugs from their phosphate prodrugs T Heimbach, DM Oh, LY Li, N Rodrı́guez-Hornedo, G Garcia, D Fleisher International journal of pharmaceutics 261 (1), 81-92, 2003 | 104 | 2003 |
tRNA-guanine transglycosylase from Escherichia coli: gross tRNA structural requirements for recognition AW Curnow, FL Kung, KA Koch, GA Garcia Biochemistry 32 (19), 5239-5246, 1993 | 104 | 1993 |
Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis V Molodtsov, NT Scharf, MA Stefan, GA Garcia, KS Murakami Molecular microbiology 103 (6), 1034-1045, 2017 | 100 | 2017 |
TRANSFER-RNA-GUANINE TRANSGLYCOSYLASE FROM ESCHERICHIA-COLI-MINIMAL TRANSFER-RNA STRUCTURE AND SEQUENCE REQUIREMENTS FOR RECOGNITION AW Curnow, GA Garcia JOURNAL OF BIOLOGICAL CHEMISTRY 270 (29), 17264-17267, 1995 | 92* | 1995 |
tRNA-guanine Transglycosylase from Escherichia coli Minimal tRNA Structure and Sequence Requirements for Recognition AW Curnow, GA Garcia Journal of Biological Chemistry 270 (29), 17264-17267, 1995 | 92 | 1995 |
Characterization of the human tRNA-guanine transglycosylase: Confirmation of the heterodimeric subunit structure YC Chen, VP Kelly, SV Stachura, GA Garcia Rna 16 (5), 958-968, 2010 | 80 | 2010 |
Kinetics and mechanism of benzoylformate decarboxylase using carbon-13 and solvent deuterium isotope effects on benzoylformate and benzoylformate analogs PM Weiss, GA Garcia, GL Kenyon, WW Cleland, PF Cook Biochemistry 27 (6), 2197-2205, 1988 | 78 | 1988 |
X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins V Molodtsov, IN Nawarathne, NT Scharf, PD Kirchhoff, HDH Showalter, ... Journal of medicinal chemistry 56 (11), 4758-4763, 2013 | 65 | 2013 |
tRNA-guanine transglycosylase from Escherichia coli: structure-activity studies investigating the role of the aminomethyl substituent of the heterocyclic substrate PreQ1 GC Hoops, LB Townsend, GA Garcia Biochemistry 34 (46), 15381-15387, 1995 | 64 | 1995 |
Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitro JK Hurt, S Olgen, GA Garcia Nucleic acids research 35 (14), 4905-4913, 2007 | 62 | 2007 |
Rifamycin inhibition of WT and Rif-resistant Mycobacterium tuberculosis and Escherichia coli RNA polymerases in vitro SK Gill, GA Garcia Tuberculosis 91 (5), 361-369, 2011 | 58 | 2011 |
Transglycosylation: a mechanism for RNA modification (and editing?) GA Garcia, JD Kittendorf Bioorganic chemistry 33 (3), 229-251, 2005 | 58 | 2005 |
tRNA–guanine transglycosylase from E. coli: a ping-pong kinetic mechanism is consistent with nucleophilic catalysis DAM Goodenough-Lashua, GA Garcia Bioorganic chemistry 31 (4), 331-344, 2003 | 56 | 2003 |
tRNA-guanine transglycosylase from Escherichia coli: overexpression, purification and quaternary structure GA Garcia, KA Koch, S Chong Journal of molecular biology 231 (2), 489-497, 1993 | 52 | 1993 |