Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling P Marcato, CA Dean, RZ Liu, KM Coyle, M Bydoun, M Wallace, ... Molecular oncology 9 (1), 17-31, 2015 | 145 | 2015 |
Autophagic homeostasis is required for the pluripotency of cancer stem cells T Sharif, E Martell, C Dai, BE Kennedy, P Murphy, DR Clements, Y Kim, ... Autophagy 13 (2), 264-284, 2017 | 127 | 2017 |
Core needle biopsy of breast cancer tumors increases distant metastases in a mouse model EG Mathenge, CA Dean, D Clements, A Vaghar-Kashani, S Photopoulos, ... Neoplasia 16 (11), 950-960, 2014 | 112 | 2014 |
Reovirus in cancer therapy: an evidence-based review D Clements, E Helson, SA Gujar, PWK Lee Oncolytic virotherapy, 69-82, 2014 | 91 | 2014 |
Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation S Gujar, R Dielschneider, D Clements, E Helson, M Shmulevitz, ... Molecular Therapy 21 (2), 338-347, 2013 | 84 | 2013 |
Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors JG Pol, S Levesque, ST Workenhe, S Gujar, F Le Boeuf, DR Clements, ... Oncoimmunology 7 (12), e1503032, 2018 | 79 | 2018 |
Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms SA Gujar, D Clements, R Dielschneider, E Helson, P Marcato, PWK Lee British journal of cancer 110 (1), 83-93, 2014 | 77 | 2014 |
Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy R Hill, M Rabb, PA Madureira, D Clements, SA Gujar, DM Waisman, ... Cell death & disease 4 (9), e791-e791, 2013 | 72 | 2013 |
The NAD+ salvage pathway modulates cancer cell viability via p73 T Sharif, DG Ahn, RZ Liu, E Pringle, E Martell, C Dai, A Nunokawa, ... Cell Death & Differentiation 23 (4), 669-680, 2016 | 71 | 2016 |
The NAD+ salvage pathway supports PHGDH-driven serine biosynthesis JP Murphy, MA Giacomantonio, JA Paulo, RA Everley, BE Kennedy, ... Cell reports 24 (9), 2381-2391. e5, 2018 | 68 | 2018 |
TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway S Almasi, AM Sterea, W Fernando, DR Clements, P Marcato, DW Hoskin, ... Scientific reports 9 (1), 4182, 2019 | 61 | 2019 |
Epigenetic Silencing of TAP1 in Aldefluor+ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion M Sultan, D Vidovic, AS Paine, TT Huynh, KM Coyle, ML Thomas, ... Stem Cells 36 (5), 641-654, 2018 | 56 | 2018 |
MHC-I ligand discovery using targeted database searches of mass spectrometry data: implications for T-cell immunotherapies JP Murphy, P Konda, DJ Kowalewski, H Schuster, D Clements, Y Kim, ... Journal of proteome research 16 (4), 1806-1816, 2017 | 53 | 2017 |
RTN4 knockdown dysregulates the AKT pathway, destabilizes the cytoskeleton, and enhances paclitaxel-induced cytotoxicity in cancers GP Pathak, R Shah, BE Kennedy, JP Murphy, D Clements, P Konda, ... Molecular Therapy 26 (8), 2019-2033, 2018 | 46 | 2018 |
Dendritic cells in oncolytic virus-based anti-cancer therapy Y Kim, DR Clements, AM Sterea, HW Jang, SA Gujar, PWK Lee Viruses 7 (12), 6506-6525, 2015 | 46 | 2015 |
The NAD+ synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target LZ Pan, DG Ahn, T Sharif, D Clements, S Gujar, PWK Lee Cell Cycle 13 (6), 1041-1048, 2014 | 45 | 2014 |
Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy A Prokopi, CH Tripp, B Tummers, F Hornsteiner, S Spoeck, JC Crawford, ... Journal for immunotherapy of cancer 9 (1), 2021 | 39 | 2021 |
Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1 KM Coyle, JP Murphy, D Vidovic, A Vaghar-Kashani, CA Dean, M Sultan, ... Oncotarget 7 (28), 44096, 2016 | 39 | 2016 |
Newly recruited CD11b+, GR-1+, Ly6Chigh myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus DR Clements, AM Sterea, Y Kim, E Helson, CA Dean, A Nunokawa, ... The Journal of Immunology 194 (9), 4397-4412, 2015 | 39 | 2015 |
TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway. S Almasi, C Yu Long, A Sterea, DR Clements, S Gujar, Y El Hiani Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG …, 2019 | 32 | 2019 |