Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS) CS Constantinescu, N Farooqi, K O'Brien, B Gran British journal of pharmacology 164 (4), 1079-1106, 2011 | 1701 | 2011 |
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo … BM Segal, CS Constantinescu, A Raychaudhuri, L Kim, R Fidelus-Gort, ... The Lancet Neurology 7 (9), 796-804, 2008 | 558 | 2008 |
Treatment of neuromyelitis optica with rituximab A Jacob, BG Weinshenker, I Violich, N McLinskey, L Krupp, RJ Fox, ... Arch Neurol 65 (11), 1443-8, 2008 | 539 | 2008 |
Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis RA Dineen, J Vilisaar, J Hlinka, CM Bradshaw, PS Morgan, ... Brain 132 (1), 239-249, 2009 | 464 | 2009 |
Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS L Kappos, A Traboulsee, C Constantinescu, JP Eralinna, F Forrestal, ... Neurology 67 (6), 944-953, 2006 | 380 | 2006 |
Diagnosis and management of Neuro-Behçet’s disease: international consensus recommendations S Kalra, A Silman, G Akman-Demir, S Bohlega, A Borhani-Haghighi, ... Journal of neurology 261, 1662-1676, 2014 | 359 | 2014 |
Fatigue in multiple sclerosis—a brief review I Induruwa, CS Constantinescu, B Gran Journal of the neurological sciences 323 (1-2), 9-15, 2012 | 307 | 2012 |
Cannabinoids and the immune system: an overview R Tanasescu, CS Constantinescu Immunobiology 215 (8), 588-597, 2010 | 291 | 2010 |
Validation of the multiple sclerosis international quality of life questionnaire MC Simeoni, P Auquier, O Fernandez, P Flachenecker, S Stecchi, ... Multiple Sclerosis Journal 14 (2), 219-230, 2008 | 252 | 2008 |
Tumor necrosis factor α and lymphotoxin α are not required for induction of acute experimental autoimmune encephalomyelitis K Frei, HP Eugster, M Bopst, CS Constantinescu, E Lavi, A Fontana The Journal of experimental medicine 185 (12), 2177-2182, 1997 | 238 | 1997 |
A prospective study of conditions associated with multiple sclerosis in a cohort of 658 consecutive outpatients attending a multiple sclerosis clinic LJ Edwards, CS Constantinescu Multiple Sclerosis Journal 10 (5), 575-581, 2004 | 237 | 2004 |
Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study A Manouchehrinia, CR Tench, J Maxted, RH Bibani, J Britton, ... Brain 136 (7), 2298-2304, 2013 | 222 | 2013 |
Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus P Tarpey, S Thomas, N Sarvananthan, U Mallya, S Lisgo, CJ Talbot, ... Nature genetics 38 (11), 1242-1244, 2006 | 216 | 2006 |
Antibodies against IL-12 prevent superantigen-induced and spontaneous relapses of experimental autoimmune encephalomyelitis CS Constantinescu, M Wysocka, B Hilliard, ES Ventura, E Lavi, ... The Journal of Immunology 161 (9), 5097-5104, 1998 | 207 | 1998 |
TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function MH Nyirenda, L Sanvito, PJ Darlington, K O’Brien, GX Zhang, ... The Journal of Immunology 187 (5), 2278-2290, 2011 | 205 | 2011 |
Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis RBC Kavia, D De Ridder, CS Constantinescu, CG Stott, CJ Fowler Multiple Sclerosis Journal 16 (11), 1349-1359, 2010 | 203 | 2010 |
Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells FJ Hartmann, M Khademi, J Aram, S Ammann, I Kockum, ... Nature communications 5 (1), 5056, 2014 | 197 | 2014 |
Glatiramer acetate (Copaxone) treatment in relapsing–remitting MS: quantitative MR assessment Y Ge, RI Grossman, JK Udupa, J Fulton, CS Constantinescu, ... Neurology 54 (4), 813-817, 2000 | 191 | 2000 |
Astrocytes as antigen‐presenting cells: expression of IL‐12/IL‐23 CS Constantinescu, M Tani, RM Ransohoff, M Wysocka, B Hilliard, ... Journal of neurochemistry 95 (2), 331-340, 2005 | 183 | 2005 |
Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death A Athanasiou, AB Clarke, AE Turner, NM Kumaran, S Vakilpour, PA Smith, ... Biochemical and biophysical research communications 364 (1), 131-137, 2007 | 170 | 2007 |