Synthesis of α-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group M Tosin, PV Murphy Organic Letters 4 (21), 3675-3678, 2002 | 104 | 2002 |
Biosynthesis of the putative siderophore erythrochelin requires unprecedented crosstalk between separate nonribosomal peptide gene clusters O Lazos, M Tosin, AL Slusarczyk, S Boakes, J Cortés, PJ Sidebottom, ... Chemistry & Biology 17 (2), 160-173, 2010 | 100 | 2010 |
In vitro reconstruction of tetronate RK-682 biosynthesis Y Sun, F Hahn, Y Demydchuk, J Chettle, M Tosin, H Osada, PF Leadlay Nature chemical biology 6 (2), 99-101, 2010 | 81 | 2010 |
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ... Nature communications 12 (1), 2511, 2021 | 64 | 2021 |
Glycosidation Reactions of Silyl Ethers with Conformationally Inverted Donors Derived from Glucuronic Acid: Stereoselective Synthesis of Glycosides and 2‐Deoxyglycosides M Poláková, N Pitt, M Tosin, PV Murphy Angewandte Chemie 116 (19), 2572-2575, 2004 | 62 | 2004 |
Glycosidation–Anomerisation Reactions of 6,1‐Anhydroglucopyranuronic Acid and Anomerisation of β‐D‐Glucopyranosiduronic Acids Promoted by SnCl4 C O'Brien, M Poláková, N Pitt, M Tosin, PV Murphy Chemistry–A European Journal 13 (3), 902-909, 2007 | 57 | 2007 |
Development of carbohydrate-based scaffolds for restricted presentation of recognition groups. Extension to divalent ligands and implications for the structure of dimerized … PV Murphy, H Bradley, M Tosin, N Pitt, GM Fitzpatrick, WK Glass The Journal of Organic Chemistry 68 (14), 5692-5704, 2003 | 57* | 2003 |
Insights into protein-protein and enzyme-substrate interactions in modular polyketide synthases L Tran, RW Broadhurst, M Tosin, A Cavalli, KJ Weissman Chemistry & biology 17 (7), 705-716, 2010 | 55 | 2010 |
Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery F Alberti, DJ Leng, I Wilkening, L Song, M Tosin, C Corre Chemical science 10 (2), 453-463, 2019 | 49 | 2019 |
Insights into lasalocid A ring formation by chemical chain termination in vivo M Tosin, L Smith, PF Leadlay Angewandte Chemie International Edition 50 (50), 11930-11933, 2011 | 49 | 2011 |
Malonyl carba (dethia)‐and Malonyl oxa (dethia)‐coenzyme A as Tools for Trapping Polyketide Intermediates M Tosin, D Spiteller, JB Spencer ChemBioChem 10 (10), 1714-1723, 2009 | 49 | 2009 |
Structural characterization of polyketides using high mass accuracy tandem mass spectrometry RH Wills, M Tosin, PB O’Connor Analytical chemistry 84 (20), 8863-8870, 2012 | 45 | 2012 |
Insights into the stereospecificity of ketoreduction in a modular polyketide synthase DH Kwan, M Tosin, N Schläger, F Schulz, PF Leadlay Organic & biomolecular chemistry 9 (7), 2053-2056, 2011 | 45 | 2011 |
Chemical probes for the functionalization of polyketide intermediates E Riva, I Wilkening, S Gazzola, WMA Li, L Smith, PF Leadlay, M Tosin Angewandte Chemie 126 (44), 12138-12143, 2014 | 44 | 2014 |
Insights into 6‐Methylsalicylic Acid Bio‐assembly by Using Chemical Probes JS Parascandolo, J Havemann, HK Potter, F Huang, E Riva, J Connolly, ... Angewandte Chemie 128 (10), 3524-3528, 2016 | 43 | 2016 |
Synthetic Chain Terminators Off‐Load Intermediates from a Type I Polyketide Synthase M Tosin, L Betancor, E Stephens, WM Ariel Li, JB Spencer, PF Leadlay ChemBioChem 11 (4), 539-546, 2010 | 43 | 2010 |
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba (dethia)-N-acetyl cysteamines M Tosin, Y Demydchuk, JS Parascandolo, CB Per, FJ Leeper, PF Leadlay Chemical Communications 47 (12), 3460-3462, 2011 | 40 | 2011 |
Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with … S André, T Velasco-Torrijos, R Leyden, S Gouin, M Tosin, PV Murphy, ... Organic & biomolecular chemistry 7 (22), 4715-4725, 2009 | 40 | 2009 |
Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the … M Tosin, PV Murphy The Journal of Organic Chemistry 70 (10), 4107-4117, 2005 | 40 | 2005 |
A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis W Tao, ME Yurkovich, S Wen, KE Lebe, M Samborskyy, Y Liu, A Yang, ... Chemical Science 7 (1), 376-385, 2016 | 39 | 2016 |