Fluoro ketone inhibitors of hydrolytic enzymes MH Gelb, JP Svaren, RH Abeles Biochemistry 24 (8), 1813-1817, 1985 | 461 | 1985 |
NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli J Svaren, BR Sevetson, ED Apel, DB Zimonjic, NC Popescu, J Milbrandt Molecular and cellular biology, 1996 | 447 | 1996 |
Associations between early life stress and gene methylation in children SE Romens, J McDonald, J Svaren, SD Pollak Child development 86 (1), 303-309, 2015 | 358 | 2015 |
EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression R Nagarajan, J Svaren, N Le, T Araki, M Watson, J Milbrandt Neuron 30 (2), 355-368, 2001 | 309 | 2001 |
The molecular machinery of myelin gene transcription in Schwann cells J Svaren, D Meijer Glia 56 (14), 1541-1551, 2008 | 302 | 2008 |
MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes H Bujalka, M Koenning, S Jackson, VM Perreau, B Pope, CM Hay, ... PLoS biology 11 (8), e1001625, 2013 | 270 | 2013 |
Transcription factors vs nucleosomes: regulation of the PH05 promoter in yeast J Svaren, W Hörz Trends in biochemical sciences 22 (3), 93-97, 1997 | 240 | 1997 |
EGR1 target genes in prostate carcinoma cells identified by microarray analysis J Svaren, T Ehrig, SA Abdulkadir, MU Ehrengruber, MA Watson, ... Journal of Biological Chemistry 275 (49), 38524-38531, 2000 | 223 | 2000 |
Impaired prostate tumorigenesis in Egr1-deficient mice SA Abdulkadir, Z Qu, E Garabedian, SK Song, TJ Peters, J Svaren, ... Nature medicine 7 (1), 101-107, 2001 | 206 | 2001 |
Activation of luteinizing hormone β gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1 C Dorn, Q Ou, J Svaren, PA Crawford, Y Sadovsky Journal of Biological Chemistry 274 (20), 13870-13876, 1999 | 206 | 1999 |
HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination Y Chen, H Wang, SO Yoon, X Xu, MO Hottiger, J Svaren, KA Nave, ... Nature neuroscience 14 (4), 437-441, 2011 | 186 | 2011 |
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells Y Poitelon, C Lopez-Anido, K Catignas, C Berti, M Palmisano, ... Nature neuroscience 19 (7), 879-887, 2016 | 179 | 2016 |
The structure and assembly of active chromatin J Svaren, R Chalkley Trends in Genetics 6, 52-56, 1990 | 175 | 1990 |
A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter. U Venter, J Svaren, J Schmitz, A Schmid, W Hörz The EMBO journal 13 (20), 4848-4855, 1994 | 170 | 1994 |
Functional Consequences of Mutations in the Early Growth Response 2 Gene (EGR2) Correlate with Severity of Human Myelinopathies LE Warner, J Svaren, J Milbrandt, JR Lupski Human molecular genetics 8 (7), 1245-1251, 1999 | 159 | 1999 |
The transactivation domain of Pho4 is required for nucleosome disruption at the PHO5 promoter. J Svaren, J Schmitz, W Hörz The EMBO journal 13 (20), 4856-4862, 1994 | 152 | 1994 |
Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain AH Swirnoff, ED Apel, J Svaren, BR Sevetson, DB Zimonjic, NC Popescu, ... Molecular and cellular biology 18 (1), 512-524, 1998 | 146 | 1998 |
PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models HT Zhao, S Damle, K Ikeda-Lee, S Kuntz, J Li, A Mohan, A Kim, G Hung, ... The Journal of clinical investigation 128 (1), 359-368, 2018 | 144 | 2018 |
Nab proteins are essential for peripheral nervous system myelination N Le, R Nagarajan, JYT Wang, J Svaren, C LaPash, T Araki, RE Schmidt, ... Nature neuroscience 8 (7), 932-940, 2005 | 140 | 2005 |
NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex R Srinivasan, GM Mager, RM Ward, J Mayer, J Svaren Journal of Biological Chemistry 281 (22), 15129-15137, 2006 | 136 | 2006 |