Sequential treatment of SH‐SY5Y cells with retinoic acid and brain‐derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor‐dependent, human neuron … M Encinas, M Iglesias, Y Liu, H Wang, A Muhaisen, V Cena, C Gallego, ... Journal of neurochemistry 75 (3), 991-1003, 2000 | 946 | 2000 |
Extracellular‐regulated kinases and phosphatidylinositol 3‐kinase are involved in brain‐derived neurotrophic factor‐mediated survival and neuritogenesis of the neuroblastoma … M Encinas, M Iglesias, N Llecha, JX Comella Journal of neurochemistry 73 (4), 1409-1421, 1999 | 305 | 1999 |
Oxidative stress and proinflammatory cytokines contribute to demyelination and axonal damage in a cerebellar culture model of neuroinflammation A Di Penta, B Moreno, S Reix, B Fernandez-Diez, M Villanueva, O Errea, ... PloS one 8 (2), e54722, 2013 | 254 | 2013 |
Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal … RM Soler, X Dolcet, M Encinas, J Egea, JR Bayascas, JX Comella Journal of neuroscience 19 (21), 9160-9169, 1999 | 235 | 1999 |
A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis KJM Marler, E Becker-Barroso, A Martínez, M Llovera, C Wentzel, ... Journal of Neuroscience 28 (48), 12700-12712, 2008 | 211 | 2008 |
Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12 N Badiola, C Penas, A Minano-Molina, B Barneda-Zahonero, R Fadó, ... Cell death & disease 2 (4), e149-e149, 2011 | 191 | 2011 |
c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway M Encinas, MG Tansey, BA Tsui-Pierchala, JX Comella, J Milbrandt, ... Journal of Neuroscience 21 (5), 1464-1472, 2001 | 191 | 2001 |
Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease A Gomez‐Arboledas, JC Davila, E Sanchez‐Mejias, V Navarro, ... Glia 66 (3), 637-653, 2018 | 176 | 2018 |
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function C McDermott-Roe, J Ye, R Ahmed, XM Sun, A Serafín, J Ware, L Bottolo, ... Nature 478 (7367), 114-118, 2011 | 173 | 2011 |
Activation of phosphatidylinositol 3‐kinase, but not extracellular‐regulated kinases, is necessary to mediate brain‐derived neurotrophic factor‐induced motoneuron survival X Dolcet, J Egea, RM Soler, D Martin‐Zanca, JX Comella Journal of neurochemistry 73 (2), 521-531, 1999 | 170 | 1999 |
Terminal sprouting in mouse neuromuscular junctions poisoned with botulinum type A toxin: morphological and electrophysiological features D Angaut-Petit, J Molgo, JX Comella, L Faille, N Tabti Neuroscience 37 (3), 799-808, 1990 | 161 | 1990 |
6‐Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK‐mediated, p53‐independent activation of Bax and PUMA M Gomez‐Lazaro, MF Galindo, CG Concannon, MF Segura, ... Journal of neurochemistry 104 (6), 1599-1612, 2008 | 155 | 2008 |
Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate M Gomez-Lazaro, MF Galindo, RMMF De Mera, FJ Fernandez-Gómez, ... Molecular pharmacology 71 (3), 736-743, 2007 | 154 | 2007 |
Proteasome inhibitors induce death but activate NF-κB on endometrial carcinoma cell lines and primary culture explants X Dolcet, D Llobet, M Encinas, J Pallares, A Cabero, JA Schoenenberger, ... Journal of Biological Chemistry 281 (31), 22118-22130, 2006 | 147 | 2006 |
Switch from caspase-dependent to caspase-independent death during heart development: essential role of endonuclease G in ischemia-induced DNA processing of differentiated … N Bahi, J Zhang, M Llovera, M Ballester, JX Comella, D Sanchis Journal of Biological Chemistry 281 (32), 22943-22952, 2006 | 130 | 2006 |
Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway X Dolcet, RM Soler, TW Gould, J Egea, RW Oppenheim, JX Comella Molecular and Cellular Neuroscience 18 (6), 619-631, 2001 | 130 | 2001 |
PC12 cells have caveolae that contain TrkA: caveolae-disrupting drugs inhibit nerve growth factor-induced, but not epidermal growth factor-induced, MAPK phosphorylation S Peiró, JX Comella, C Enrich, D Martı́n-Zanca, N Rocamora Journal of Biological Chemistry 275 (48), 37846-37852, 2000 | 128 | 2000 |
Presynaptic actions of botulinal neurotoxins at vertebrate neuromuscular junctions. J Molgo, JX Comella, D Angaut-Petit, M Pecot-Dechavassine, N Tabti, ... Journal de physiologie 84 (2), 152-166, 1990 | 122 | 1990 |
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis VJ Yuste, I Sánchez-López, C Solé, RS Moubarak, JR Bayascas, X Dolcet, ... Journal of Biological Chemistry 280 (42), 35670-35683, 2005 | 117 | 2005 |
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling C Sole, X Dolcet, MF Segura, H Gutierrez, MT Diaz-Meco, R Gozzelino, ... The Journal of cell biology 167 (3), 479-492, 2004 | 116 | 2004 |