| ABC transporter-mediated multidrug-resistant cancer H Amawi, HM Sim, AK Tiwari, SV Ambudkar, S Shukla Drug Transporters in Drug Disposition, Effects and Toxicity, 549-580, 2019 | 213 | 2019 |
| Molecular basis of the polyspecificity of P-glycoprotein (ABCB1): recent biochemical and structural studies EE Chufan, HM Sim, SV Ambudkar Advances in cancer research 125, 71-96, 2015 | 157 | 2015 |
| Multiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1) EE Chufan, K Kapoor, HM Sim, S Singh, TT Talele, SR Durell, ... PloS one 8 (12), e82463, 2013 | 121 | 2013 |
| Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein) HM Sim, CY Lee, PLR Ee, ML Go European Journal of Pharmaceutical Sciences 35 (4), 293-306, 2008 | 104 | 2008 |
| Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo X Zhao, J Xie, X Chen, HM Sim, X Zhang, Y Liang, S Singh, TT Talele, ... Molecular pharmacology 82 (1), 47-58, 2012 | 96 | 2012 |
| Overexpression of ATP-binding cassette transporter ABCG2 as a potential mechanism of acquired resistance to vemurafenib in BRAF (V600E) mutant cancer cells CP Wu, HM Sim, YH Huang, YC Liu, SH Hsiao, HW Cheng, YQ Li, ... Biochemical pharmacology 85 (3), 325-334, 2013 | 89 | 2013 |
| Aurones as modulators of ABCG2 and ABCB1: synthesis and structure–activity relationships HM Sim, KY Loh, WK Yeo, CY Lee, ML Go ChemMedChem 6 (4), 713-724, 2011 | 85 | 2011 |
| Saracatinib (AZD0530) is a potent modulator of ABCB1‐mediated multidrug resistance in vitro and in vivo KJ Liu, JH He, XD Su, HM Sim, JD Xie, XG Chen, F Wang, YJ Liang, ... International journal of cancer 132 (1), 224-235, 2013 | 56 | 2013 |
| Human ABCB1 (P-glycoprotein) and ABCG2 mediate resistance to BI 2536, a potent and selective inhibitor of Polo-like kinase 1 CP Wu, SH Hsiao, HM Sim, SY Luo, WC Tuo, HW Cheng, YQ Li, ... Biochemical pharmacology 86 (7), 904-913, 2013 | 42 | 2013 |
| Synthesis and antimicrobial activity of N1-benzyl or N1-benzyloxy-1, 6-dihydro-1, 3, 5-triazine-2, 4-diamines X Ma, ST Tan, CL Khoo, HM Sim, LW Chan, WK Chui Bioorganic & medicinal chemistry letters 21 (18), 5428-5431, 2011 | 39 | 2011 |
| In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs HM Sim, CP Wu, SV Ambudkar, ML Go Biochemical pharmacology 82 (11), 1562-1571, 2011 | 27 | 2011 |
| ARRY‐334543 Reverses Multidrug Resistance by Antagonizing the Activity of ATP‐Binding Cassette Subfamily G Member 2 DS Wang, A Patel, HM Sim, YK Zhang, YJ Wang, RJ Kathawala, H Zhang, ... Journal of cellular biochemistry 115 (8), 1381-1391, 2014 | 20 | 2014 |
| Multidrug resistance in cancer: a tale of ABC drug transporters K Kapoor, HM Sim, SV Ambudkar Molecular mechanisms of tumor cell resistance to chemotherapy: Targeted …, 2013 | 14 | 2013 |
| Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations HM Sim, J Bhatnagar, EE Chufan, K Kapoor, SV Ambudkar Biochemistry 52 (41), 7327-7338, 2013 | 10 | 2013 |
| ABC transporter modulatory drugs from marine sources: A new approach to overcome drug resistance in cancer A Patel, DS Wang, HM Sim, SV Ambudkar, ZS Chen Resistance to Targeted ABC Transporters in Cancer, 183-208, 2015 | 2 | 2015 |
| Human ABCB1 and ABCG2 confer acquired resistance to Polo-like kinase 1 inhibitors, BI 2536, volasertib and GSK641364 CP Wu, HM Sim, SV Ambudkar Cancer Research 74 (19_Supplement), 766-766, 2014 | 1 | 2014 |
| Chemical Flexibility of P-Glycoprotein for Interaction with Substrates and Modulators EE Chufan, K Kapoor, HM Sim, S Durrell, SV Ambudkar Biophysical Journal 104 (2), 200a, 2013 | 1 | 2013 |
| Mapping conformational changes associated with the catalytic cycle of human P-glycoprotein (ABCB1) J Bhatnagar, HM Sim, E Georgieva, K Kapoor, E Chufan, S Ohnuma, ... Biophysical Journal 102 (3), 606a-607a, 2012 | 1 | 2012 |
| Erratum to: ABC Transporter Modulatory Drugs from Marine Sources: A New Approach to Overcome Drug Resistance in Cancer A Patel, DS Wang, HM Sim, SV Ambudkar, ZS Chen Resistance to Targeted ABC Transporters in Cancer, E1-E1, 2015 | | 2015 |
| Chemical and structural flexibility contribute to the broad substrate and modulator specificity of multidrug resistance-linked P-glycoprotein (ABCB1). SV Ambudkar, EE Chufan, K Kapoor, SR Durell, HM Sim CANCER RESEARCH 73 (8), 2013 | | 2013 |
