| Accelerated neurodegeneration through chaperone-mediated oligomerization of tau LJ Blair, BA Nordhues, SE Hill, KM Scaglione, JC O’Leary, SN Fontaine, ... The Journal of clinical investigation 123 (10), 4158-4169, 2013 | 310 | 2013 |
| Chemical manipulation of hsp70 ATPase activity regulates tau stability UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ... Journal of neuroscience 29 (39), 12079-12088, 2009 | 274 | 2009 |
| Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ... Journal of Neuroscience 33 (22), 9498-9507, 2013 | 266 | 2013 |
| The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules UK Jinwal, J Koren III, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ... The Journal of Neuroscience 30 (2), 591-599, 2010 | 229 | 2010 |
| Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ... Molecular neurodegeneration 5, 1-11, 2010 | 202 | 2010 |
| Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ... Journal of Neuroscience 30 (46), 15374-15382, 2010 | 136 | 2010 |
| A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51 JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ... PloS one 6 (9), e24840, 2011 | 135 | 2011 |
| Imbalance of Hsp70 family variants fosters tau accumulation UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ... The FASEB Journal 27 (4), 1450, 2013 | 123 | 2013 |
| Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency JJ Sabbagh, JC O'Leary III, LJ Blair, T Klengel, BA Nordhues, ... PloS one 9 (9), e107241, 2014 | 111 | 2014 |
| Hsc70 rapidly engages tau after microtubule destabilization UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ... Journal of biological chemistry 285 (22), 16798-16805, 2010 | 103 | 2010 |
| Facilitating Akt clearance via manipulation of Hsp70 activity and levels J Koren, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ... Journal of biological chemistry 285 (4), 2498-2505, 2010 | 100 | 2010 |
| The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau JR Jones, MD Lebar, UK Jinwal, JF Abisambra, J Koren III, L Blair, ... Journal of natural products 74 (1), 38-44, 2011 | 86 | 2011 |
| The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics UK Jinwal, JH Trotter, JF Abisambra, J Koren, LY Lawson, GD Vestal, ... Journal of Biological Chemistry 286 (19), 16976-16983, 2011 | 80 | 2011 |
| Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism A Suntharalingam, JF Abisambra, JC O'Leary, J Koren, B Zhang, MK Joe, ... Journal of Biological Chemistry 287 (48), 40661-40669, 2012 | 76 | 2012 |
| Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein UK Jinwal, JF Abisambra, J Zhang, S Dharia, JC O'Leary, T Patel, ... Journal of Biological Chemistry 287 (29), 24814-24820, 2012 | 73 | 2012 |
| Hsp70 ATPase modulators as therapeutics for Alzheimer’s and other neurodegenerative diseases UK Jinwal, J Koren III, JC O’Leary III, JR Jones, JF Abisambra, CA Dickey Molecular and cellular pharmacology 2 (2), 43, 2010 | 59 | 2010 |
| Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance J Koren III, Y Miyata, J Kiray, JC O'Leary III, L Nguyen, J Guo, LJ Blair, X Li, ... PloS one 7 (4), e35566, 2012 | 50 | 2012 |
| The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance JC O’Leary III, B Zhang, J Koren III, L Blair, C A Dickey CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2013 | 49 | 2013 |
| Neuronal life span versus health span: principles of natural selection at work in the degenerating brain JC O’Leary, J Koren, CA Dickey Journal of Molecular Neuroscience 45, 467-472, 2011 | 3 | 2011 |
| Grp94 triage of mutant myocilin through ERAD subverts a more efficient autophagic clearance mechanism A Suntharalingam, JF Abisambra, JC O’Leary 3rd, J Koren 3rd, B Zhang, ... J Biol Chem 287, 40661-40669, 2012 | 2 | 2012 |
