Molecular mechanism of action of microtubule-stabilizing anticancer agents AE Prota, K Bargsten, D Zurwerra, JJ Field, JF Díaz, KH Altmann, ... Science 339 (6119), 587-590, 2013 | 523 | 2013 |
Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function JJ Field, A Kanakkanthara, JH Miller Bioorganic & medicinal chemistry 22 (18), 5050-5059, 2014 | 269 | 2014 |
The binding sites of microtubule-stabilizing agents JJ Field, JF Díaz, JH Miller Chemistry & biology 20 (3), 301-315, 2013 | 150 | 2013 |
Microtubule-Stabilizing Activity of Zampanolide, a Potent Macrolide Isolated from the Tongan Marine Sponge Cacospongia mycofijiensis JJ Field, AJ Singh, A Kanakkanthara, T Halafihi, PT Northcote, JH Miller Journal of medicinal chemistry 52 (22), 7328-7332, 2009 | 124 | 2009 |
Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α, β-heterodimers and microtubules JJ Field, B Pera, E Calvo, A Canales, D Zurwerra, C Trigili, ... Chemistry & biology 19 (6), 686-698, 2012 | 105 | 2012 |
Marine invertebrate natural products that target microtubules JH Miller, JJ Field, A Kanakkanthara, JG Owen, AJ Singh, PT Northcote Journal of natural products 81 (3), 691-702, 2018 | 53 | 2018 |
Structurally diverse hamigerans from the New Zealand marine sponge Hamigera tarangaensis: NMR-directed isolation, structure elucidation and antifungal activity AJ Singh, JD Dattelbaum, JJ Field, Z Smart, EF Woolly, JM Barber, ... Organic & Biomolecular Chemistry 11 (46), 8041-8051, 2013 | 39 | 2013 |
Polyhalogenated Indoles from the Red Alga Rhodophyllis membranacea: The First Isolation of Bromo-Chloro-Iodo Secondary Metabolites VH Woolner, CM Jones, JJ Field, NH Fadzilah, AB Munkacsi, JH Miller, ... Journal of natural products 79 (3), 463-469, 2016 | 36 | 2016 |
The Nitrogenous Hamigerans: Unusual Amino Acid-Derivatized Aromatic Diterpenoid Metabolites from the New Zealand Marine Sponge Hamigera tarangaensis JD Dattelbaum, AJ Singh, JJ Field, JH Miller, PT Northcote The Journal of Organic Chemistry 80 (1), 304-312, 2015 | 35 | 2015 |
Zampanolide, a microtubule-stabilizing agent, is active in resistant cancer cells and inhibits cell migration JJ Field, PT Northcote, I Paterson, KH Altmann, JF Díaz, JH Miller International journal of molecular sciences 18 (5), 971, 2017 | 30 | 2017 |
A previously undescribed tubulin binder JJ Field, AB Waight, PD Senter Proceedings of the National Academy of Sciences 111 (38), 13684-13685, 2014 | 21 | 2014 |
Use of substitute Nonidet P-40 nonionic detergents in intracellular tubulin polymerization assays for screening of microtubule targeting agents S Sinha, JJ Field, JH Miller Biochemistry and Cell Biology 95 (3), 379-384, 2017 | 20 | 2017 |
βI-tubulin mutations in the laulimalide/peloruside binding site mediate drug sensitivity by altering drug–tubulin interactions and microtubule stability A Kanakkanthara, MR Rowe, JJ Field, PT Northcote, PH Teesdale-Spittle, ... Cancer letters 365 (2), 251-260, 2015 | 20 | 2015 |
Zampanolide binding to tubulin indicates cross-talk of taxane site with colchicine and nucleotide sites JJ Field, B Pera, JE Gallego, E Calvo, J Rodríguez-Salarichs, ... Journal of natural products 81 (3), 494-505, 2017 | 19 | 2017 |
Synthesis of a simplified triazole analogue of pateamine A AH Cumming, SL Brown, X Tao, C Cuyamendous, JJ Field, JH Miller, ... Organic & biomolecular chemistry 14 (22), 5117-5127, 2016 | 13 | 2016 |
31st annual meeting and associated programs of the society for immunotherapy of cancer (Sitc 2016): Part two: National harbor, md, USA. 9-13 November 2016 C Ager, M Reilley, C Nicholas, T Bartkowiak, A Jaiswal, M Curran, ... Journal for ImmunoTherapy of Cancer 4, 107-221, 2016 | 12 | 2016 |
Microtubule-stabilizing properties of the avocado-derived toxins (+)-(R)-persin and (+)-(R)-tetrahydropersin in cancer cells and activity of related synthetic analogs JJ Field, A Kanakkanthara, DG Brooke, S Sinha, SD Pillai, WA Denny, ... Investigational new drugs 34, 277-289, 2016 | 12 | 2016 |
Synthesis of Bioactive Side‐Chain Analogues of TAN‐2483B KK Somarathne, JAJ McCone, A Brackovic, JLP Rivera, JR Fulton, ... Chemistry–An Asian Journal 14 (8), 1230-1237, 2019 | 11 | 2019 |
Synthesis of mycothiol conjugate analogues and evaluation of their antimycobacterial activity SW Riordan, JJ Field, HM Corkran, N Dasyam, BL Stocker, MSM Timmer, ... Bioorganic & medicinal chemistry letters 25 (10), 2152-2155, 2015 | 10 | 2015 |
Understanding the mechanism of 2FF-induced immune modulation JJ Field, NM Okeley, W Zeng, CL Law, PD Senter, SJ Gardai Cancer Research 76 (14_Supplement), 4005-4005, 2016 | 8 | 2016 |