| Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability DC Radisky, DD Levy, LE Littlepage, H Liu, CM Nelson, JE Fata, D Leake, ... Nature 436 (7047), 123-127, 2005 | 1450 | 2005 |
| Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells KE Richards, AE Zeleniak, ML Fishel, J Wu, LE Littlepage, R Hill Oncogene 36 (13), 1770-1778, 2017 | 710 | 2017 |
| Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA R Mendez, LE Hake, T Andresson, LE Littlepage, JV Ruderman, ... Nature 404 (6775), 302-307, 2000 | 428 | 2000 |
| GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model H Kouros-Mehr, SK Bechis, EM Slorach, LE Littlepage, M Egeblad, ... Cancer cell 13 (2), 141-152, 2008 | 420 | 2008 |
| Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit LE Littlepage, JV Ruderman Genes & development 16 (17), 2274-2285, 2002 | 387 | 2002 |
| Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression LE Littlepage, MD Sternlicht, N Rougier, J Phillips, E Gallo, Y Yu, ... Cancer research 70 (6), 2224-2234, 2010 | 275 | 2010 |
| Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A LE Littlepage, H Wu, T Andresson, JK Deanehan, LT Amundadottir, ... Proceedings of the National Academy of Sciences 99 (24), 15440-15445, 2002 | 273 | 2002 |
| Aurora A, meiosis and mitosis R Crane, B Gadea, L Littlepage, H Wu, JV Ruderman Biology of the Cell 96 (3), 215-229, 2004 | 215 | 2004 |
| A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway K Kessenbrock, GJP Dijkgraaf, DA Lawson, LE Littlepage, P Shahi, ... Cell stem cell 13 (3), 300-313, 2013 | 161 | 2013 |
| Activity of the APCCdh1 form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p JN Huang, I Park, E Ellingson, LE Littlepage, D Pellman The Journal of cell biology 154 (1), 85-94, 2001 | 150 | 2001 |
| Coevolution of cancer and stromal cellular responses LE Littlepage, M Egeblad, Z Werb Cancer cell 7 (6), 499-500, 2005 | 146 | 2005 |
| The fibroblastic coconspirator in cancer progression M Egeblad, LE Littlepage, Z Werb Cold Spring Harbor symposia on quantitative biology 70, 383-388, 2005 | 124 | 2005 |
| The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis R Romero-Moreno, KJ Curtis, TR Coughlin, MC Miranda-Vergara, S Dutta, ... Nature communications 10 (1), 4404, 2019 | 123 | 2019 |
| CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression AS Adler, LE Littlepage, M Lin, TLA Kawahara, DJ Wong, Z Werb, ... Cancer research 68 (2), 506-515, 2008 | 89 | 2008 |
| Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217 JJ Northey, AS Barrett, I Acerbi, MK Hayward, S Talamantes, IS Dean, ... The Journal of clinical investigation 130 (11), 5721-5737, 2020 | 84 | 2020 |
| The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression LE Littlepage, AS Adler, H Kouros-Mehr, G Huang, J Chou, SR Krig, ... Cancer discovery 2 (7), 638-651, 2012 | 81 | 2012 |
| Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling EK Breuer, D Fukushiro-Lopes, A Dalheim, M Burnette, J Zartman, S Kaja, ... Cell death & disease 10 (3), 180, 2019 | 75 | 2019 |
| Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers K Takai, AP Drain, DA Lawson, LE Littlepage, M Karpuj, K Kessenbrock, ... Genes & development 32 (3-4), 244-257, 2018 | 63 | 2018 |
| Aggressive breast cancer in western Kenya has early onset, high proliferation, and immune cell infiltration RT Sawe, M Kerper, S Badve, J Li, M Sandoval-Cooper, J Xie, Z Shi, ... BMC cancer 16, 1-15, 2016 | 56 | 2016 |
| Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy B Kim, J Shin, J Wu, DT Omstead, T Kiziltepe, LE Littlepage, B Bilgicer Journal of Controlled Release 322, 530-541, 2020 | 54 | 2020 |
