Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment A Dirkse, A Golebiewska, T Buder, PV Nazarov, A Muller, S Poovathingal, ... Nature communications 10 (1), 1787, 2019 | 468 | 2019 |
Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ... PloS one 10 (5), e0126522, 2015 | 369 | 2015 |
Cell fate decision as high-dimensional critical state transition M Mojtahedi, A Skupin, J Zhou, IG Castaño, RYY Leong-Quong, H Chang, ... PLoS biology 14 (12), e2000640, 2016 | 332 | 2016 |
Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures C Sousa, A Golebiewska, SK Poovathingal, T Kaoma, Y Pires‐Afonso, ... EMBO reports 19 (11), e46171, 2018 | 243 | 2018 |
Pro-inflammatory macrophages sustain pyruvate oxidation through pyruvate dehydrogenase for the synthesis of itaconate and to enable cytokine expression J Meiser, L Krämer, SC Sapcariu, N Battello, J Ghelfi, AF D'Herouel, ... Journal of Biological Chemistry 291 (8), 3932-3946, 2016 | 242 | 2016 |
How does intracellular Ca2+ oscillate: by chance or by the clock? A Skupin, H Kettenmann, U Winkler, M Wartenberg, H Sauer, SC Tovey, ... Biophysical journal 94 (6), 2404-2411, 2008 | 211 | 2008 |
Clustering of InsP 3 receptors by InsP 3 retunes their regulation by InsP 3 and Ca 2+ SA Taufiq-Ur-Rahman, M Falcke, CW Taylor Nature 458 (7238), 655-659, 2009 | 191* | 2009 |
The contribution of microglia to neuroinflammation in Parkinson’s disease K Badanjak, S Fixemer, S Smajić, A Skupin, A Grünewald International Journal of Molecular Sciences 22 (9), 4676, 2021 | 170 | 2021 |
Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes K Thurley, SC Tovey, G Moenke, VL Prince, A Meena, AP Thomas, ... Science signaling 7 (331), ra59-ra59, 2014 | 127 | 2014 |
Calcium signals driven by single channel noise A Skupin, H Kettenmann, M Falcke PLoS computational biology 6 (8), e1000870, 2010 | 112 | 2010 |
Critical transitions in chronic disease: transferring concepts from ecology to systems medicine C Trefois, PMA Antony, J Goncalves, A Skupin, R Balling Current opinion in biotechnology 34, 48-55, 2015 | 108 | 2015 |
Fundamental properties of Ca2+ signals K Thurley, A Skupin, R Thul, M Falcke Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (8), 1185-1194, 2012 | 99 | 2012 |
SARS-CoV-2 transmission risk from asymptomatic carriers: results from a mass screening programme in Luxembourg P Wilmes, J Zimmer, J Schulz, F Glod, L Veiber, L Mombaerts, ... The Lancet Regional Health–Europe 4, 2021 | 98 | 2021 |
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology A Golebiewska, AC Hau, A Oudin, D Stieber, YA Yabo, V Baus, ... Acta Neuropathologica 140, 919-949, 2020 | 95 | 2020 |
Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1−/− zebrafish S Soman, M Keatinge, M Moein, M Da Costa, H Mortiboys, A Skupin, ... European Journal of Neuroscience 45 (4), 528-535, 2017 | 88 | 2017 |
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ... Stem cell reports 12 (5), 878-889, 2019 | 87 | 2019 |
Aneuploidy underlies a multicellular phenotypic switch Z Tan, M Hays, GA Cromie, EW Jeffery, AC Scott, V Ahyong, A Sirr, ... Proceedings of the National Academy of Sciences 110 (30), 12367-12372, 2013 | 86 | 2013 |
Protocols and programs for high-throughput growth and aging phenotyping in yeast PP Jung, N Christian, DP Kay, A Skupin, CL Linster PloS one 10 (3), e0119807, 2015 | 76 | 2015 |
From puffs to global Ca2+ signals: how molecular properties shape global signals A Skupin, M Falcke Chaos: An Interdisciplinary Journal of Nonlinear Science 19 (3), 2009 | 63 | 2009 |
Mitochondrial morphology provides a mechanism for energy buffering at synapses GC Garcia, TM Bartol, S Phan, EA Bushong, G Perkins, TJ Sejnowski, ... Scientific reports 9 (1), 18306, 2019 | 62 | 2019 |