The TRPM8 protein is a testosterone receptor: II. Functional evidence for an ionotropic effect of testosterone on TRPM8 S Asuthkar, L Demirkhanyan, X Sun, PA Elustondo, V Krishnan, ... Journal of Biological Chemistry 290 (5), 2670-2688, 2015 | 126 | 2015 |
Oxytocin modulates nociception as an agonist of pain-sensing TRPV1 Y Nersesyan, L Demirkhanyan, D Cabezas-Bratesco, V Oakes, R Kusuda, ... Cell reports 21 (6), 1681-1691, 2017 | 121 | 2017 |
Multifaceted Mechanisms of HIV-1 Entry Inhibition by Human α-Defensin*♦ LH Demirkhanyan, M Marin, S Padilla-Parra, C Zhan, K Miyauchi, ... Journal of Biological Chemistry 287 (34), 28821-28838, 2012 | 105 | 2012 |
TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival L Mittermeier, L Demirkhanyan, B Stadlbauer, A Breit, C Recordati, ... Proceedings of the National Academy of Sciences 116 (10), 4706-4715, 2019 | 104 | 2019 |
The TRPM8 protein is a testosterone receptor: I. Biochemical evidence for direct TRPM8-testosterone interactions S Asuthkar, PA Elustondo, L Demirkhanyan, X Sun, P Baskaran, ... Journal of Biological Chemistry 290 (5), 2659-2669, 2015 | 94 | 2015 |
Structural basis of temperature sensation by the TRP channel TRPV3 AK Singh, LL McGoldrick, L Demirkhanyan, M Leslie, E Zakharian, ... Nature structural & molecular biology 26 (11), 994-998, 2019 | 92 | 2019 |
TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells S Asuthkar, KK Velpula, PA Elustondo, L Demirkhanyan, E Zakharian Oncotarget 6 (19), 17221, 2015 | 82 | 2015 |
Contribution of inorganic polyphosphate towards regulation of mitochondrial free calcium ME Solesio, L Demirkhanyan, E Zakharian, EV Pavlov Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (6), 1317-1325, 2016 | 49 | 2016 |
The immunosuppressant macrolide tacrolimus activates cold-sensing TRPM8 channels JM Arcas, A González, K Gers-Barlag, O González-González, F Bech, ... Journal of Neuroscience 39 (6), 949-969, 2019 | 41 | 2019 |
Sub-inhibitory concentrations of human α-defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum L Demirkhanyan, M Marin, W Lu, GB Melikyan PLoS pathogens 9 (6), e1003431, 2013 | 36 | 2013 |
Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii LL McGoldrick, AK Singh, L Demirkhanyan, TY Lin, RG Casner, ... Nature communications 10 (1), 4180, 2019 | 34 | 2019 |
Stimulation-dependent gating of TRPM3 channel in planar lipid bilayers K Uchida, L Demirkhanyan, S Asuthkar, A Cohen, M Tominaga, ... The FASEB Journal 30 (3), 1306, 2016 | 33 | 2016 |
High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer S Asuthkar, L Demirkhanyan, SR Mueting, A Cohen, E Zakharian Oncotarget 8 (8), 12877, 2017 | 20 | 2017 |
Epistatic Effects of the Protease/Chaperone HflB on Some Damaged Forms of the Escherichia coli Ammonium Channel AmtB WB Inwood, JA Hall, KS Kim, L Demirkhanyan, D Wemmer, H Zgurskaya, ... Genetics 183 (4), 1327-1340, 2009 | 12 | 2009 |
Inorganic polyphosphate as an energy source in tumorigenesis J Boyineni, ST Sredni, NV Margaryan, L Demirkhanyan, M Tye, ... Oncotarget 11 (50), 4613, 2020 | 11 | 2020 |
Circular dumbbell miR‑34a‑3p and‑5p suppresses pancreatic tumor cell‑induced angiogenesis and activates macrophages M Gnanamony, L Demirkhanyan, L Ge, P Sojitra, S Bapana, JA Norton, ... Oncology Letters 21 (1), 1-1, 2021 | 7 | 2021 |
Role of polyphosphate in cancer cell proliferation L Demirkhanyan, P Elustondo, E Pavlov, E Zakharian Biophysical Journal 106 (2), 753a, 2014 | 6 | 2014 |
TRPM3 gating in planar lipid bilayers defines peculiar agonist specificity L Demirkhanyan, K Uchida, M Tominaga, E Zakharian Channels 10 (4), 258-260, 2016 | 3 | 2016 |
Role of TRPV1 channels in glioma cell viability and survival Y Nersesyan, S Asuthkar, KK Velpula, X Sun, L Demirkhanyan, ... Biophysical Journal 108 (2), 124a, 2015 | 3 | 2015 |
Ketone bodies and their polymers in heart failure and type 2 diabetes: lessons learned from the ketone ester diet PN Thai, L Demirkhanyan, MT King, E Zakharian, R Veech, S Schaefer, ... Biophysical Journal 116 (3), 2a-3a, 2019 | 2 | 2019 |