Herbal drug discovery for the treatment of nonalcoholic fatty liver disease T Yan, N Yan, P Wang, Y Xia, H Hao, G Wang, FJ Gonzalez Acta Pharmaceutica Sinica B 10 (1), 3-18, 2020 | 163 | 2020 |
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors X Lv, Y Xia, M Finel, J Wu, G Ge, L Yang Acta Pharmaceutica Sinica B 9 (2), 258-278, 2019 | 74 | 2019 |
Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis T Yan, Y Luo, N Yan, K Hamada, N Zhao, Y Xia, P Wang, C Zhao, D Qi, ... Hepatology 77 (1), 239-255, 2023 | 47 | 2023 |
An Optimized Two‐Photon Fluorescent Probe for Biological Sensing and Imaging of Catechol‐O‐Methyltransferase P Wang, YL Xia, LW Zou, XK Qian, TY Dou, Q Jin, SY Li, Y Yu, DD Wang, ... Chemistry–A European Journal 23 (45), 10800-10807, 2017 | 37 | 2017 |
The pathophysiological function of non-gastrointestinal farnesoid X receptor N Yan, T Yan, Y Xia, H Hao, G Wang, FJ Gonzalez Pharmacology & therapeutics 226, 107867, 2021 | 35 | 2021 |
Design, synthesis and biological evaluation of esculetin derivatives as anti-tumour agents P Wang, YL Xia, Y Yu, JX Lu, LW Zou, L Feng, GB Ge, L Yang RSC Advances 5 (66), 53477-53483, 2015 | 29 | 2015 |
Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin YL Xia, SC Liang, LL Zhu, GB Ge, GY He, J Ning, X Lv, XC Ma, L Yang, ... Drug metabolism and pharmacokinetics 29 (2), 135-140, 2014 | 29 | 2014 |
Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3 Y Xia, P Wang, N Yan, FJ Gonzalez, T Yan Cell death & disease 12 (2), 174, 2021 | 26 | 2021 |
Synthesis and structure-activity relationship of daphnetin derivatives as potent antioxidant agents Y Xia, C Chen, Y Liu, G Ge, T Dou, P Wang Molecules 23 (10), 2476, 2018 | 24 | 2018 |
Methylation, glucuronidation, and sulfonation of daphnetin in human hepatic preparations in vitro: metabolic profiling, pathway comparison, and bioactivity analysis SC Liang, YL Xia, J Hou, GB Ge, JW Zhang, YQ He, JY Wang, XY Qi, ... Journal of pharmaceutical sciences 105 (2), 808-816, 2016 | 24 | 2016 |
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes X Lv, J Hou, YL Xia, J Ning, GY He, P Wang, GB Ge, ZL Xiu, L Yang Drug Metabolism and Pharmacokinetics 30 (5), 358-365, 2015 | 21 | 2015 |
Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation, while potently inhibiting estradiol-3-O-glucuronidation L Zhu, L Xiao, Y Xia, K Zhou, H Wang, M Huang, G Ge, Y Wu, G Wu, ... Toxicology and Applied Pharmacology 283 (2), 109-116, 2015 | 21 | 2015 |
Combined analysis of metagenomic data revealed consistent changes of gut microbiome structure and function in inflammatory bowel disease Y Xia, J Wang, X Fang, T Dou, L Han, C Yang Journal of Applied Microbiology 131 (6), 3018-3031, 2021 | 18 | 2021 |
Comparison of hepatotoxicity associated with new BCR-ABL tyrosine kinase inhibitors vs imatinib among patients with chronic myeloid leukemia: a systematic review and meta-analysis Z Wang, X Wang, Z Wang, Y Feng, Y Jia, L Jiang, Y Xia, J Cao, Y Liu JAMA Network Open 4 (7), e2120165-e2120165, 2021 | 18 | 2021 |
Synthesis and structure-activity relationship of coumarins as potent Mcl-1 inhibitors for cancer treatment YL Xia, JJ Wang, SY Li, Y Liu, FJ Gonzalez, P Wang, GB Ge Bioorganic & medicinal chemistry 29, 115851, 2021 | 18 | 2021 |
Inhibition of human catechol-O-methyltransferase-mediated dopamine O-methylation by daphnetin and its Phase II metabolites SC Liang, GB Ge, YL Xia, D Pei-Pei, W Ping, XY Qi, T Cai-Xia, Y Ling Xenobiotica 47 (6), 498-504, 2017 | 17 | 2017 |
Identification of a new heterocyclic scaffold for inhibitors of the polo-box domain of polo-like kinase 1 CN Alverez, JE Park, KS Toti, Y Xia, KW Krausz, G Rai, JK Bang, ... Journal of medicinal chemistry 63 (22), 14087-14117, 2020 | 16 | 2020 |
A highly selective fluorescent probe for sensing activities of catechol-O-methyltransferase in complex biological samples XK Qian, P Wang, YL Xia, TY Dou, Q Jin, DD Wang, DC Hao, XL Bi, ... Sensors and Actuators B: Chemical 231, 615-623, 2016 | 16 | 2016 |
Structural modifications at the C-4 position strongly affect the glucuronidation of 6, 7-dihydroxycoumarins YL Xia, GB Ge, P Wang, SC Liang, YQ He, J Ning, XK Qian, Y Li, L Yang Drug Metabolism and Disposition 43 (4), 553-560, 2015 | 15 | 2015 |
Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation G He, J Troberg, X Lv, YL Xia, LL Zhu, J Ning, GB Ge, M Finel, L Yang Xenobiotica 48 (2), 109-116, 2018 | 14 | 2018 |